| Synergy between the KEAP1/NRF2 and PI3K pathways drives non-small-cell lung cancer with an altered immune microenvironment SA Best, DP De Souza, A Kersbergen, AN Policheni, S Dayalan, D Tull, ... Cell metabolism 27 (4), 935-943. e4, 2018 | 204 | 2018 |
| Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia GJ Liu, L Cimmino, JG Jude, Y Hu, MT Witkowski, MD McKenzie, ... Genes & development 28 (12), 1337-1350, 2014 | 117 | 2014 |
| Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer SA Best, PM Gubser, S Sethumadhavan, A Kersbergen, YLN Abril, ... Cell metabolism 34 (6), 874-887. e6, 2022 | 96 | 2022 |
| EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival NY Fu, AC Rios, B Pal, R Soetanto, ATL Lun, K Liu, T Beck, SA Best, ... Nature Cell Biology 17 (4), 365-375, 2015 | 95 | 2015 |
| Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma SA Best, S Ding, A Kersbergen, X Dong, JY Song, Y Xie, B Reljic, K Li, ... Nature communications 10 (1), 4190, 2019 | 90 | 2019 |
| Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer TW Owens, RL Rogers, SA Best, A Ledger, AM Mooney, A Ferguson, ... Cancer research 74 (18), 5277-5286, 2014 | 81 | 2014 |
| Harnessing natural killer immunity in metastatic SCLC SA Best, JB Hess, F Souza-Fonseca-Guimaraes, J Cursons, ... Journal of Thoracic Oncology 15 (9), 1507-1521, 2020 | 79 | 2020 |
| “Keaping” a lid on lung cancer: the Keap1-Nrf2 pathway SA Best, KD Sutherland Cell Cycle 17 (14), 1696-1707, 2018 | 55 | 2018 |
| Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia MT Witkowski, L Cimmino, Y Hu, T Trimarchi, H Tagoh, MD McKenzie, ... Leukemia 29 (6), 1301-1311, 2015 | 47 | 2015 |
| A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1 JM Sheridan, ME Ritchie, SA Best, K Jiang, TJ Beck, F Vaillant, K Liu, ... BMC cancer 15, 1-13, 2015 | 43 | 2015 |
| Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary SA Best, KJ Hutt, NY Fu, F Vaillant, SH Liew, L Hartley, CL Scott, ... Development 141 (16), 3159-3164, 2014 | 42 | 2014 |
| Pro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2 D Merino, SA Best, ML Asselin-Labat, F Vaillant, B Pal, RA Dickins, ... Oncogene 34 (30), 3926-3934, 2015 | 39 | 2015 |
| From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress B Dewdney, MR Jenkins, SA Best, S Freytag, K Prasad, J Holst, ... Signal Transduction and Targeted Therapy 8 (1), 400, 2023 | 30 | 2023 |
| Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs A Kersbergen, SA Best, S Dworkin, C Ah-Cann, ME de Vries, ... Developmental biology 443 (1), 1-9, 2018 | 27 | 2018 |
| Spatial architecture of high-grade glioma reveals tumor heterogeneity within distinct domains JJD Moffet, OE Fatunla, L Freytag, J Kriel, JJ Jones, SJ Roberts-Thomson, ... Neuro-Oncology Advances 5 (1), vdad142, 2023 | 23 | 2023 |
| CCAR2 is required for proliferation and tumor maintenance in human squamous cell carcinoma SA Best, AN Nwaobasi, CD Schmults, MR Ramsey Journal of Investigative Dermatology 137 (2), 506-512, 2017 | 22 | 2017 |
| BCKDK alters the metabolism of non-small cell lung cancer Y Wang, J Xiao, W Jiang, D Zuo, X Wang, Y Jin, L Qiao, H An, L Yang, ... Translational Lung Cancer Research 10 (12), 4459, 2021 | 21 | 2021 |
| FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium SA Best, CR Harapas, A Kersbergen, V Rathi, ML Asselin-Labat, ... Oncogene 37 (46), 6096-6104, 2018 | 18 | 2018 |
| An integrated molecular grafting approach for the design of Keap1-targeted peptide inhibitors H Yin, YH Huang, SA Best, KD Sutherland, DJ Craik, CK Wang ACS Chemical Biology 16 (7), 1276-1287, 2021 | 13 | 2021 |
| A risk-reward examination of sample multiplexing reagents for single cell RNA-Seq DV Brown, CJA Anttila, L Ling, P Grave, TM Baldwin, R Munnings, ... Genomics 116 (2), 110793, 2024 | 11 | 2024 |
