| Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ... PloS one 3 (8), e3088, 2008 | 842 | 2008 |
| Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ... Nature 510 (7506), 537-541, 2014 | 467 | 2014 |
| Pathogenic DDX3X mutations impair RNA metabolism and neurogenesis during fetal cortical development AL Lennox, ML Hoye, R Jiang, BL Johnson-Kerner, LA Suit, ... Neuron 106 (3), 404-420. e8, 2020 | 179 | 2020 |
| OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells J Bunt, NE Hasselt, DA Zwijnenburg, M Hamdi, J Koster, R Versteeg, ... International journal of cancer 131 (2), E21-E32, 2012 | 112 | 2012 |
| Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance APL Marsh, D Heron, TJ Edwards, A Quartier, C Galea, C Nava, ... Nature genetics 49 (4), 511-514, 2017 | 108 | 2017 |
| YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis KW Pajtler, Y Wei, K Okonechnikov, PBG Silva, M Vouri, L Zhang, ... Nature communications 10 (1), 3914, 2019 | 96 | 2019 |
| The convergent roles of the nuclear factor I transcription factors in development and cancer KS Chen, JWC Lim, LJ Richards, J Bunt Cancer letters 410, 124-138, 2017 | 94 | 2017 |
| Astroglial-mediated remodeling of the interhemispheric midline is required for the formation of the corpus callosum I Gobius, L Morcom, R Suárez, J Bunt, P Bukshpun, W Reardon, ... Cell reports 17 (3), 735-747, 2016 | 77 | 2016 |
| Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord E Matuzelski, J Bunt, D Harkins, JWC Lim, RM Gronostajski, LJ Richards, ... Developmental Biology 432 (2), 286-297, 2017 | 67 | 2017 |
| MicroRNA-153 regulates the acquisition of gliogenic competence by neural stem cells J Tsuyama, J Bunt, LJ Richards, H Iwanari, Y Mochizuki, T Hamakubo, ... Stem cell reports 5 (3), 365-377, 2015 | 58 | 2015 |
| Identification of CUX1 as the recurrent chromosomal band 7q22 target gene in human uterine leiomyoma EFPM Schoenmakers, J Bunt, L Hermers, M Schepens, G Merkx, ... Genes, Chromosomes and Cancer 52 (1), 11-23, 2013 | 55 | 2013 |
| Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines J Bunt, TG de Haas, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, ... Molecular Cancer Research 8 (10), 1344-1357, 2010 | 54 | 2010 |
| OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels J Bunt, NA Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool Acta neuropathologica 125, 385-394, 2013 | 53 | 2013 |
| NFIB haploinsufficiency is associated with intellectual disability and macrocephaly I Schanze, J Bunt, JWC Lim, D Schanze, RJ Dean, M Alders, P Blanchet, ... The American Journal of Human Genetics 103 (5), 752-768, 2018 | 52 | 2018 |
| Understanding the uptake of nanomedicines at different stages of brain cancer using a modular nanocarrier platform and precision bispecific antibodies ZH Houston, J Bunt, KS Chen, S Puttick, CB Howard, NL Fletcher, ... ACS central science 6 (5), 727-738, 2020 | 47 | 2020 |
| Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma J Bunt, NE Hasselt, DA Zwijnenburg, J Koster, R Versteeg, M Kool PloS one 6 (10), e26058, 2011 | 45 | 2011 |
| Nuclear factor one B (NFIB) encodes a subtype-specific tumour suppressor in glioblastoma BW Stringer, J Bunt, BW Day, G Barry, PR Jamieson, KS Ensbey, ... Oncotarget 7 (20), 29306, 2016 | 42 | 2016 |
| Variants in nuclear factor I genes influence growth and development M Zenker, J Bunt, I Schanze, D Schanze, M Piper, M Priolo, EH Gerkes, ... American Journal of Medical Genetics Part C: Seminars in Medical Genetics …, 2019 | 40 | 2019 |
| The oncogenic fusion landscape in pediatric CNS neoplasms M Roosen, Z Odé, J Bunt, M Kool Acta Neuropathologica 143 (4), 427-451, 2022 | 39 | 2022 |
| Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice KS Chen, L Harris, JWC Lim, TJ Harvey, M Piper, RM Gronostajski, ... Journal of Comparative Neurology 525 (11), 2465-2483, 2017 | 39 | 2017 |
Marcel KoolPI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology UtrechtEmail được xác minh tại dkfz.de