Theo dõi
Francisco León
Francisco León
Asistant Professor
Email được xác minh tại mailbox.sc.edu
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine
SE Hemby, S McIntosh, F Leon, SJ Cutler, CR McCurdy
Addiction biology 24 (5), 874-885, 2019
1712019
Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based kratom …
S Obeng, SH Kamble, ME Reeves, LF Restrepo, A Patel, M Behnke, ...
Journal of medicinal chemistry 63 (1), 433-439, 2019
1352019
Phytochemical Characterization of the Leaves of Mitragyna Speciosa Grown in USA
F León, E Habib, JE Adkins, EB Furr, CR McCurdy, SJ Cutler
Natural Product Communications 4 (7), 1934578X0900400705, 2009
1112009
Metabolite profiling and identification of enzymes responsible for the metabolism of mitragynine, the major alkaloid of Mitragyna speciosa (kratom)
SH Kamble, A Sharma, TI King, F León, CR McCurdy, BA Avery
Xenobiotica, 0
105*
Steroidal Saponins from the Bark of Dracaena draco and Their Cytotoxic Activities
AG González, JC Hernández, F León, JI Padrón, F Estévez, J Quintana, ...
Journal of Natural Products 66 (6), 793-798, 2003
992003
Perspective on the therapeutics of anti-snake venom
I Gómez-Betancur, V Gogineni, A Salazar-Ospina, F León
Molecules 24 (18), 3276, 2019
972019
Lanostanoid Triterpenes from Laetiporus s ulph u reus and Apoptosis Induction on HL-60 Human Myeloid Leukemia Cells
F León, J Quintana, A Rivera, F Estévez, J Bermejo
Journal of natural products 67 (12), 2008-2011, 2004
962004
Patterns and reasons for kratom (Mitragyna speciosa) use among current and former opioid poly-drug users
D Singh, NJY Chear, S Narayanan, F Leon, A Sharma, CR McCurdy, ...
Journal of ethnopharmacology 249, 112462, 2020
922020
Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography …
A Sharma, SH Kamble, F León, NJY Chear, TI King, EC Berthold, ...
Drug testing and analysis 11 (8), 1162-1171, 2019
922019
New Lanostanoids from the Fungus Ganoderma concinna
AG González, F León, A Rivera, JI Padrón, J González-Plata, JC Zuluaga, ...
Journal of Natural Products 65 (3), 417-421, 2002
892002
Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for Mu-Opioid Receptor and Opioid-Like Behavioral Effects in Rats
Journal of Pharmacology and Experimental Therapeutics 376 (3), 410-427, 2021
882021
Lanostanoid Triterpenes from Ganoderma l ucidum
AG González, F León, A Rivera, CM Muñoz, J Bermejo
Journal of natural products 62 (12), 1700-1701, 1999
851999
Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
F Larit, KM Elokely, ND Chaurasiya, S Benyahia, MA Nael, F León, ...
Phytomedicine 40, 27-36, 2018
832018
The polypharmacological effects of cannabidiol
J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León
Molecules 28 (7), 3271, 2023
822023
A flavonoid with cytotoxic activity and other constituents from Centaurea africana
R Seghiri, O Boumaza, R Mekkiou, S Benayache, P Mosset, J Quintana, ...
Phytochemistry Letters 2 (3), 114-118, 2009
732009
Novel approaches, drug candidates, and targets in pain drug discovery
S Obeng, T Hiranita, F León, LR McMahon, CR McCurdy
Journal of medicinal chemistry 64 (10), 6523-6548, 2021
712021
Phenolic Compounds of Dragon's Blood from Dracaena draco
AG González, F León, L Sánchez-Pinto, JI Padrón, J Bermejo
Journal of Natural Products 63 (9), 1297-1299, 2000
702000
Icogenin, a new cytotoxic steroidal saponin isolated from Dracaena draco
JC Hernandez, F León, J Quintana, F Estévez, J Bermejo
Bioorganic & medicinal chemistry 12 (16), 4423-4429, 2004
682004
Exploration of cytochrome P450 inhibition mediated drug-drug interaction potential of kratom alkaloids
SH Kamble, A Sharma, TI King, EC Berthold, F León, PKL Meyer, ...
Toxicology letters 319, 148-154, 2020
672020
Activity of Mitragyna speciosa (“Kratom”) Alkaloids at Serotonin Receptors
F León, S Obeng, M Mottinelli, Y Chen, TI King, EC Berthold, SH Kamble, ...
Journal of medicinal chemistry 64 (18), 13510-13523, 2021
662021
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