| Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target S Lechner, MIP Malgapo, C Grätz, RR Steimbach, A Baron, P Rüther, ... Nature chemical biology 18 (8), 812-820, 2022 | 70 | 2022 |
| Decrypting drug actions and protein modifications by dose-and time-resolved proteomics J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ... Science 380 (6640), 93-101, 2023 | 59 | 2023 |
| Aza-SAHA derivatives are selective histone deacetylase 10 chemical probes that inhibit polyamine deacetylation and phenocopy HDAC10 knockout RR Steimbach, CJ Herbst-Gervasoni, S Lechner, TM Stewart, G Klinke, ... Journal of the American Chemical Society 144 (41), 18861-18875, 2022 | 25 | 2022 |
| Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid S Lechner, RR Steimbach, L Wang, ML Deline, YC Chang, T Fromme, ... Nature Communications 14 (1), 3548, 2023 | 18 | 2023 |
| A region‐resolved proteomic map of the human brain enabled by high‐throughput proteomics J Tüshaus, A Sakhteman, S Lechner, M The, E Mucha, C Krisp, J Schlegel, ... The EMBO Journal 42 (23), e114665, 2023 | 17 | 2023 |
| Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics S Eckert, N Berner, K Kramer, A Schneider, J Müller, S Lechner, ... Nature biotechnology, 1-10, 2024 | 12 | 2024 |
| Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition C Glas, E Naydenova, S Lechner, N Wössner, L Yang, JCB Dietschreit, ... European Journal of Medicinal Chemistry 240, 114594, 2022 | 12 | 2022 |
| Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics YC Chang, C Gnann, RR Steimbach, FP Bayer, S Lechner, A Sakhteman, ... Cell reports 43 (6), 2024 | 6 | 2024 |
| Targeting LC3/GABARAP for degrader development and autophagy modulation MP Schwalm, J Dopfer, A Kumar, FA Greco, N Bauer, F Löhr, J Heering, ... bioRxiv, 2023.10. 05.560930, 2023 | 4 | 2023 |
| Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets MP Schwalm, J Dopfer, A Kumar, FA Greco, N Bauer, F Löhr, J Heering, ... Nature Communications 15 (1), 10204, 2024 | 1 | 2024 |
| High-throughput screening and proteomic characterization of compounds targeting myeloid-derived suppressor cells J Krumm, E Petrova, S Lechner, J Mergner, HH Boehm, A Prestipino, ... Molecular & Cellular Proteomics 22 (9), 2023 | | 2023 |
| Chemoproteomics-based target deconvolution and selectivity profiling of Histone Deacetylase inhibitors S Lechner Technische Universität München, 2023 | | 2023 |
| Chemoproteomic target deconvolution of lipoic acid reveals Histone Deacetylases as the main targets B Kuster, S Lechner, R Steimbach, L Wang, P Matthias, A Miller, ... | | 2022 |
| Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target (Apr, 10.1038/s41589-022-01015-5, 2022) S Lechner, MIP Malgapo, C Graetz, RR Steimbach, A Baron, P Ruether, ... NATURE CHEMICAL BIOLOGY 18 (8), 913-913, 2022 | | 2022 |