Theo dõi
Mihir Metkar
Mihir Metkar
Moderna therapeutics
Email được xác minh tại modernatx.com
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness
KS Corbett, DK Edwards, SR Leist, OM Abiona, S Boyoglu-Barnum, ...
Nature 586 (7830), 567-571, 2020
16322020
Higher-Order Organization Principles of Pre-translational mRNPs
M Metkar, H Ozadam, BR Lajoie, M Imakaev, LA Mirny, J Dekker, ...
Molecular Cell 72 (4), P715-726.E3, 2018
692018
Coronavirus rna vaccines
M Metkar, V Presnyak, G Stewart-Jones
US Patent App. 17/000,215, 2021
482021
Tailor made: the art of therapeutic mRNA design
M Metkar, CS Pepin, MJ Moore
Nature Reviews Drug Discovery 23 (1), 67-83, 2024
452024
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved alternative splicing nonsense-mediated decay pathways
C Kovalak, S Donovan, AA Bicknell, M Metkar, MJ Moore
Genome biology 22, 1-21, 2021
242021
Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay
AA Bicknell, DW Reid, MC Licata, AK Jones, YM Cheng, M Li, CJ Hsiao, ...
Cell reports 43 (4), 2024
172024
Multi-proline-substituted coronavirus spike protein vaccines
G Stewart-Jones, M Metkar, V Presnyak
US Patent App. 18/028,126, 2023
42023
Sars-cov-2 mrna domain vaccines
G Stewart-Jones, A Carfi, SM Elbashir, M Metkar
US Patent App. 17/797,784, 2023
42023
Coronavirus rna vaccines
M Metkar, V Presnyak
US Patent App. 17/518,542, 2022
32022
mRNA secondary structure prediction using utility-scale quantum computers
D Alevras, M Metkar, T Yamamoto, V Kumar, T Friedhoff, JE Park, ...
2024 IEEE International Conference on Quantum Computing and Engineering (QCE …, 2024
22024
Coronavirus rna vaccines
G Stewart-Jones, E Narayanan, H Bennett, A Carfi, M Metkar, V Presnyak
US Patent App. 17/796,208, 2023
22023
RIPPLiT and ChimeraTie: High throughput tools for understanding higher order RNP structures
M Metkar
University of Massachusetts Medical School, 2018
12018
Polynucleotides encoding relaxin for the treatment of fibrosis and/or cardiovascular disease
MA Zimmer, X Yan, M Metkar, D Reid
US Patent App. 18/695,076, 2025
2025
ENGINEERED POLYNUCLEOTIDES FOR CELL-TYPE OR MICROENVIRONMENT-SPECIFIC EXPRESSION
R Jain, BR Fritz, M Metkar
US Patent App. 18/569,888, 2024
2024
Deep sequencing of pre-translational mRNPs reveals hidden flux through evolutionarily conserved AS-NMD pathways [preprint]
C Kovalak, M Metkar, MJ Moore
2019
Higher-Order Organization Principles of Pre-translational mRNPs [preprint]
M Metkar, H Ozadam, BR Lajoie, M Imakaev, LA Mirny, J Dekker, ...
2018
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