SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell 181 (5), 1016-1035. e19, 2020 | 2497 | 2020 |
Engineering stem cell organoids X Yin, BE Mead, H Safaee, R Langer, JM Karp, O Levy Cell stem cell 18 (1), 25-38, 2016 | 849 | 2016 |
Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease FEO Holmberg, JB Seidelin, X Yin, BE Mead, Z Tong, Y Li, JM Karp, ... EMBO molecular medicine 9 (5), 558-570, 2017 | 86 | 2017 |
Generating iPSCs: translating cell reprogramming science into scalable and robust biomanufacturing strategies M Silva, L Daheron, H Hurley, K Bure, R Barker, AJ Carr, D Williams, ... Cell stem cell 16 (1), 13-17, 2015 | 78 | 2015 |
HCA Lung Biological Network. Electronic address: lung-network@ humancellatlas. org; HCA Lung Biological Network. SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in … CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ... Cell 181 (5), 1016-1035, 2020 | 55 | 2020 |
Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells Z Tong, K Martyn, A Yang, X Yin, BE Mead, N Joshi, NE Sherman, ... Biomaterials 154, 60-73, 2018 | 50 | 2018 |
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types BE Mead, J Ordovas-Montanes, AP Braun, LE Levy, P Bhargava, ... BMC biology 16, 1-24, 2018 | 46 | 2018 |
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation BE Mead, K Hattori, L Levy, S Imada, N Goto, M Vukovic, D Sze, ... Nature Biomedical Engineering 6 (4), 476-494, 2022 | 44 | 2022 |
Bioprocess decision support tool for scalable manufacture of extracellular vesicles KS Ng, JA Smith, MP McAteer, BE Mead, J Ware, FO Jackson, A Carter, ... Biotechnology and bioengineering 116 (2), 307-319, 2019 | 40 | 2019 |
All models are wrong, but some organoids may be useful BE Mead, JM Karp Genome biology 20 (1), 66, 2019 | 38 | 2019 |
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes AS Genshaft, CGK Ziegler, CN Tzouanas, BE Mead, AM Jaeger, ... Nature communications 12 (1), 4995, 2021 | 37 | 2021 |
Cellular and transcriptional diversity over the course of human lactation SK Nyquist, P Gao, TKJ Haining, MR Retchin, Y Golan, RS Drake, K Kolb, ... Proceedings of the National Academy of Sciences 119 (15), e2121720119, 2022 | 34 | 2022 |
Ionic osmolytes and intracellular calcium regulate tissue production in chondrocytes cultured in a 3D charged hydrogel NL Farnsworth, BE Mead, LR Antunez, AE Palmer, SJ Bryant Matrix Biology 40, 17-26, 2014 | 28 | 2014 |
Extracellular vesicles commercial potential as byproducts of cell manufacturing for research and therapeutic use JA Smith, KS Ng, BE Mead, S Dopson, B Reeve, J Edwards, DA Brindley Bioprocess Int 13 (4), 20-26, 2015 | 22 | 2015 |
A resistance-sensing mechanical injector for the precise delivery of liquids to target tissue GD Chitnis, MKS Verma, J Lamazouade, M Gonzalez-Andrades, K Yang, ... Nature biomedical engineering 3 (8), 621-631, 2019 | 19 | 2019 |
Fluorescence-based tracing of transplanted intestinal epithelial cells using confocal laser endomicroscopy F Bergenheim, JB Seidelin, MT Pedersen, BE Mead, KB Jensen, JM Karp, ... Stem Cell Research & Therapy 10, 1-12, 2019 | 16 | 2019 |
Acute experimental barrier injury triggers ulcerative colitis–specific innate hyperresponsiveness and ulcerative colitis–type microbiome changes in humans JB Seidelin, MI Bahl, TR Licht, BE Mead, JM Karp, JV Johansen, LB Riis, ... Cellular and molecular gastroenterology and hepatology 12 (4), 1281-1296, 2021 | 13 | 2021 |
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression AM Tsankov, MH Wadsworth, V Akopian, J Charlton, SJ Allon, ... Development 146 (19), dev174722, 2019 | 12 | 2019 |
Telomerase expression marks transitional growth-associated skeletal progenitor/stem cells DL Carlone, RD Riba-Wolman, LT Deary, A Tovaglieri, L Jiang, ... Stem Cells 39 (3), 296-305, 2021 | 10 | 2021 |
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival CN Tzouanas, MS Sherman, JES Shay, AJ Rubin, BE Mead, TT Dao, ... Biorxiv, 2023 | 5 | 2023 |