Stimulation of autophagy improves endoplasmic reticulum stress–induced diabetes E Bachar-Wikstrom, JD Wikstrom, Y Ariav, B Tirosh, N Kaiser, E Cerasi, ... Diabetes 62 (4), 1227-1237, 2013 | 215 | 2013 |
CHOP is a critical regulator of acetaminophen-induced hepatotoxicity D Uzi, L Barda, V Scaiewicz, M Mills, T Mueller, A Gonzalez-Rodriguez, ... Journal of Hepatology 59 (3), 495-503, 2013 | 189 | 2013 |
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response B Tirosh, NN Iwakoshi, LH Glimcher, HL Ploegh Journal of Biological Chemistry 281 (9), 5852-5860, 2006 | 167 | 2006 |
Transferrin as a luminal target for negatively charged liposomes in the inflamed colonic mucosa B Tirosh, N Khatib, Y Barenholz, A Nissan, A Rubinstein Molecular pharmaceutics 6 (4), 1083-1091, 2009 | 162 | 2009 |
The rationale for peptide drug delivery to the colon and the potential of polymeric carriers as effective tools A Rubinstein, B Tirosh, M Baluom, T Nassar, A David, R Radai, ... Journal of controlled release 46 (1-2), 59-73, 1997 | 150 | 1997 |
Combined dendritic cell cryotherapy of tumor induces systemic antimetastatic immunity A Machlenkin, O Goldberger, B Tirosh, A Paz, I Volovitz, E Bar-Haim, ... Clinical cancer research 11 (13), 4955-4961, 2005 | 140 | 2005 |
HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response E Merquiol, D Uzi, T Mueller, D Goldenberg, Y Nahmias, RJ Xavier, ... PLoS one 6 (9), e24660, 2011 | 128 | 2011 |
ER stress and its regulator X‐box‐binding protein‐1 enhance polyIC‐induced innate immune response in dendritic cells F Hu, X Yu, H Wang, D Zuo, C Guo, H Yi, B Tirosh, JR Subjeck, X Qiu, ... European journal of immunology 41 (4), 1086-1097, 2011 | 123 | 2011 |
Controlled release oral drug delivery system A Rubinstein, R Radai, M Friedman, B Tirosh, M Baluom, T Nassar US Patent 6,692,766, 2004 | 122 | 2004 |
Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation B Tirosh, MH Furman, D Tortorella, HL Ploegh Journal of Biological Chemistry 278 (9), 6664-6672, 2003 | 120 | 2003 |
SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity A Demishtein, M Fraiberg, D Berko, B Tirosh, Z Elazar, A Navon Autophagy 13 (10), 1697-1708, 2017 | 116 | 2017 |
MHC class I‐restricted epitope spreading in the context of tumor rejection following vaccination with a single immunodominant CTL epitope K el‐Shami, B Tirosh, E Bar‐Haim, L Carmon, E Vadai, M Fridkin, ... European journal of immunology 29 (10), 3295-3301, 1999 | 115 | 1999 |
Regulated IRE1‐dependent decay participates in curtailing immunoglobulin secretion from plasma cells S Benhamron, R Hadar, T Iwawaky, JS So, AH Lee, B Tirosh European journal of immunology 44 (3), 867-876, 2014 | 104 | 2014 |
Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products B Tirosh, NN Iwakoshi, BN Lilley, AH Lee, LH Glimcher, HL Ploegh Journal of virology 79 (5), 2768-2779, 2005 | 104 | 2005 |
Mucus gel thickness and turnover in the gastrointestinal tract of the rat: response to cholinergic stimulus and implication for mucoadhesion A Rubinstein, B Tirosh Pharmaceutical research 11, 794-799, 1994 | 102 | 1994 |
XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells B Tirosh, NN Iwakoshi, LH Glimcher, HL Ploegh The Journal of experimental medicine 202 (4), 505-516, 2005 | 101 | 2005 |
Proximal tubule mTORC1 is a central player in the pathophysiology of diabetic nephropathy and its correction by SGLT2 inhibitors A Kogot-Levin, L Hinden, Y Riahi, T Israeli, B Tirosh, E Cerasi, ... Cell reports 32 (4), 2020 | 97 | 2020 |
mTOR activation promotes plasma cell differentiation and bypasses XBP-1 for immunoglobulin secretion S Benhamron, SP Pattanayak, M Berger, B Tirosh Molecular and cellular biology 35 (1), 153-166, 2015 | 97 | 2015 |
Enhanced transferrin receptor expression by proinflammatory cytokines in enterocytes as a means for local delivery of drugs to inflamed gut mucosa E Harel, A Rubinstein, A Nissan, E Khazanov, M Nadler Milbauer, ... PLoS One 6 (9), e24202, 2011 | 96 | 2011 |
The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors M Mahameed, T Wilhelm, O Darawshi, A Obiedat, WS Tommy, C Chintha, ... Cell death & disease 10 (4), 300, 2019 | 86 | 2019 |