Revisiting the role of ABC transporters in multidrug-resistant cancer RW Robey, KM Pluchino, MD Hall, AT Fojo, SE Bates, MM Gottesman Nature Reviews Cancer 18 (7), 452-464, 2018 | 1599 | 2018 |
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes K Miyake, L Mickley, T Litman, Z Zhan, R Robey, B Cristensen, M Brangi, ... Cancer research 59 (1), 8-13, 1999 | 1075 | 1999 |
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms V Sandor, S Bakke, RW Robey, MH Kang, MV Blagosklonny, J Bender, ... Clinical Cancer Research 8 (3), 718-728, 2002 | 689 | 2002 |
ABCG2: a perspective RW Robey, KKK To, O Polgar, M Dohse, P Fetsch, M Dean, SE Bates Advanced drug delivery reviews 61 (1), 3-13, 2009 | 563 | 2009 |
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells Y Honjo, CA Hrycyna, QW Yan, WY Medina-Pérez, RW Robey, ... Cancer research 61 (18), 6635-6639, 2001 | 562 | 2001 |
ABCG2: determining its relevance in clinical drug resistance RW Robey, O Polgar, J Deeken, KW To, SE Bates Cancer and Metastasis Reviews 26, 39-57, 2007 | 505 | 2007 |
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells RW Robey, WY Medina-Pérez, K Nishiyama, T Lahusen, K Miyake, ... Clinical Cancer Research 7 (1), 145-152, 2001 | 444 | 2001 |
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2 C Dai, AK Tiwari, CP Wu, X Su, SR Wang, D Liu, CR Ashby Jr, Y Huang, ... Cancer research 68 (19), 7905-7914, 2008 | 439 | 2008 |
Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity RW Robey, Y Honjo, K Morisaki, TA Nadjem, S Runge, M Risbood, ... British journal of cancer 89 (10), 1971-1978, 2003 | 433 | 2003 |
Pheophorbide a is a specific probe for ABCG2 function and inhibition RW Robey, K Steadman, O Polgar, K Morisaki, M Blayney, P Mistry, ... Cancer research 64 (4), 1242-1246, 2004 | 424 | 2004 |
Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-d-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate … ZS Chen, RW Robey, MG Belinsky, I Shchaveleva, XQ Ren, Y Sugimoto, ... Cancer research 63 (14), 4048-4054, 2003 | 423 | 2003 |
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR M de Bruin, K Miyake, T Litman, R Robey, SE Bates Cancer letters 146 (2), 117-126, 1999 | 402 | 1999 |
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2–mediated drug resistance Z Shi, XX Peng, IW Kim, S Shukla, QS Si, RW Robey, SE Bates, T Shen, ... Cancer research 67 (22), 11012-11020, 2007 | 349 | 2007 |
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells M Brangi, T Litman, M Ciotti, K Nishiyama, G Kohlhagen, C Takimoto, ... Cancer research 59 (23), 5938-5946, 1999 | 349 | 1999 |
Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance EL Volk, KM Farley, Y Wu, F Li, RW Robey, E Schneider Cancer research 62 (17), 5035-5040, 2002 | 336 | 2002 |
MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors J Jaboin, J Wild, H Hamidi, C Khanna, CJ Kim, R Robey, SE Bates, ... Cancer research 62 (21), 6108-6115, 2002 | 310 | 2002 |
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity P Giannakakou, R Robey, T Fojo, MV Blagosklonny Oncogene 20 (29), 3806-3813, 2001 | 307 | 2001 |
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2) RW Robey, Y Honjo, A van de Laar, K Miyake, JT Regis, T Litman, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1512 (2), 171-182, 2001 | 305 | 2001 |
Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors C Grant, F Rahman, R Piekarz, C Peer, R Frye, RW Robey, ER Gardner, ... Expert review of anticancer therapy 10 (7), 997-1008, 2010 | 294 | 2010 |
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity MV Blagosklonny, R Robey, DL Sackett, L Du, F Traganos, ... Molecular cancer therapeutics 1 (11), 937-941, 2002 | 282 | 2002 |