Theo dõi
Robert W. Robey
Robert W. Robey
Chemist, National Cancer Institute
Email được xác minh tại mail.nih.gov
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Revisiting the role of ABC transporters in multidrug-resistant cancer
RW Robey, KM Pluchino, MD Hall, AT Fojo, SE Bates, MM Gottesman
Nature Reviews Cancer 18 (7), 452-464, 2018
15992018
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes
K Miyake, L Mickley, T Litman, Z Zhan, R Robey, B Cristensen, M Brangi, ...
Cancer research 59 (1), 8-13, 1999
10751999
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms
V Sandor, S Bakke, RW Robey, MH Kang, MV Blagosklonny, J Bender, ...
Clinical Cancer Research 8 (3), 718-728, 2002
6892002
ABCG2: a perspective
RW Robey, KKK To, O Polgar, M Dohse, P Fetsch, M Dean, SE Bates
Advanced drug delivery reviews 61 (1), 3-13, 2009
5632009
Acquired mutations in the MXR/BCRP/ABCP gene alter substrate specificity in MXR/BCRP/ABCP-overexpressing cells
Y Honjo, CA Hrycyna, QW Yan, WY Medina-Pérez, RW Robey, ...
Cancer research 61 (18), 6635-6639, 2001
5622001
ABCG2: determining its relevance in clinical drug resistance
RW Robey, O Polgar, J Deeken, KW To, SE Bates
Cancer and Metastasis Reviews 26, 39-57, 2007
5052007
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells
RW Robey, WY Medina-Pérez, K Nishiyama, T Lahusen, K Miyake, ...
Clinical Cancer Research 7 (1), 145-152, 2001
4442001
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2
C Dai, AK Tiwari, CP Wu, X Su, SR Wang, D Liu, CR Ashby Jr, Y Huang, ...
Cancer research 68 (19), 7905-7914, 2008
4392008
Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity
RW Robey, Y Honjo, K Morisaki, TA Nadjem, S Runge, M Risbood, ...
British journal of cancer 89 (10), 1971-1978, 2003
4332003
Pheophorbide a is a specific probe for ABCG2 function and inhibition
RW Robey, K Steadman, O Polgar, K Morisaki, M Blayney, P Mistry, ...
Cancer research 64 (4), 1242-1246, 2004
4242004
Transport of Methotrexate, Methotrexate Polyglutamates, and 17β-Estradiol 17-(β-d-glucuronide) by ABCG2: Effects of Acquired Mutations at R482 on Methotrexate …
ZS Chen, RW Robey, MG Belinsky, I Shchaveleva, XQ Ren, Y Sugimoto, ...
Cancer research 63 (14), 4048-4054, 2003
4232003
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
M de Bruin, K Miyake, T Litman, R Robey, SE Bates
Cancer letters 146 (2), 117-126, 1999
4021999
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2–mediated drug resistance
Z Shi, XX Peng, IW Kim, S Shukla, QS Si, RW Robey, SE Bates, T Shen, ...
Cancer research 67 (22), 11012-11020, 2007
3492007
Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells
M Brangi, T Litman, M Ciotti, K Nishiyama, G Kohlhagen, C Takimoto, ...
Cancer research 59 (23), 5938-5946, 1999
3491999
Overexpression of wild-type breast cancer resistance protein mediates methotrexate resistance
EL Volk, KM Farley, Y Wu, F Li, RW Robey, E Schneider
Cancer research 62 (17), 5035-5040, 2002
3362002
MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors
J Jaboin, J Wild, H Hamidi, C Khanna, CJ Kim, R Robey, SE Bates, ...
Cancer research 62 (21), 6108-6115, 2002
3102002
Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
P Giannakakou, R Robey, T Fojo, MV Blagosklonny
Oncogene 20 (29), 3806-3813, 2001
3072001
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
RW Robey, Y Honjo, A van de Laar, K Miyake, JT Regis, T Litman, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1512 (2), 171-182, 2001
3052001
Romidepsin: a new therapy for cutaneous T-cell lymphoma and a potential therapy for solid tumors
C Grant, F Rahman, R Piekarz, C Peer, R Frye, RW Robey, ER Gardner, ...
Expert review of anticancer therapy 10 (7), 997-1008, 2010
2942010
Histone deacetylase inhibitors all induce p21 but differentially cause tubulin acetylation, mitotic arrest, and cytotoxicity
MV Blagosklonny, R Robey, DL Sackett, L Du, F Traganos, ...
Molecular cancer therapeutics 1 (11), 937-941, 2002
2822002
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