Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome S Guidi, P Bonasoni, C Ceccarelli, D Santini, F Gualtieri, E Ciani, ... Brain Pathology 18 (2), 180-197, 2008 | 347 | 2008 |
Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood T Rubino, N Realini, D Braida, S Guidi, V Capurro, D Viganò, C Guidali, ... Hippocampus 19 (8), 763-772, 2009 | 342 | 2009 |
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice A Contestabile, T Fila, C Ceccarelli, P Bonasoni, L Bonapace, D Santini, ... Hippocampus 17 (8), 665-678, 2007 | 334 | 2007 |
Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome P Bianchi, E Ciani, S Guidi, S Trazzi, D Felice, G Grossi, M Fernandez, ... Journal of Neuroscience 30 (26), 8769-8779, 2010 | 259 | 2010 |
Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome S Guidi, E Ciani, P Bonasoni, D Santini, R Bartesaghi Brain Pathology 21 (4), 361-373, 2011 | 194 | 2011 |
Nitric oxide regulates cGMP‐dependent cAMP‐responsive element binding protein phosphorylation and Bcl‐2 expression in cerebellar neurons: implication for a survival role of … E Ciani, S Guidi, R Bartesaghi, A Contestabile Journal of neurochemistry 82 (5), 1282-1289, 2002 | 183 | 2002 |
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling C Fuchs, S Trazzi, R Torricella, R Viggiano, M De Franceschi, ... Neurobiology of disease 70, 53-68, 2014 | 153 | 2014 |
Timing of therapies for Down syndrome: the sooner, the better F Stagni, A Giacomini, S Guidi, E Ciani, R Bartesaghi Frontiers in behavioral neuroscience 9, 265, 2015 | 150 | 2015 |
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome S Trazzi, VM Mitrugno, E Valli, C Fuchs, S Rizzi, S Guidi, G Perini, ... Human molecular genetics 20 (8), 1560-1573, 2011 | 148 | 2011 |
Neurogenesis impairment: An early developmental defect in Down syndrome F Stagni, A Giacomini, M Emili, S Guidi, R Bartesaghi Free Radical Biology and Medicine 114, 15-32, 2018 | 120 | 2018 |
Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome P Bianchi, E Ciani, A Contestabile, S Guidi, R Bartesaghi Brain Pathology 20 (1), 106-118, 2010 | 114 | 2010 |
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder S Trazzi, C Fuchs, R Viggiano, M De Franceschi, E Valli, P Jedynak, ... Human molecular genetics 25 (18), 3887-3907, 2016 | 110 | 2016 |
Is it possible to improve neurodevelopmental abnormalities in Down syndrome? R Bartesaghi, S Guidi, E Ciani De Gruyter 22 (4), 419-455, 2011 | 108 | 2011 |
Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation E Ciani, S Guidi, G Della Valle, G Perini, R Bartesaghi, A Contestabile Journal of Biological Chemistry 277 (51), 49896-49902, 2002 | 103 | 2002 |
Prenatal pharmacotherapy rescues brain development in a Down’s syndrome mouse model S Guidi, F Stagni, P Bianchi, E Ciani, A Giacomini, M De Franceschi, ... Brain 137 (2), 380-401, 2014 | 101 | 2014 |
Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation E Ciani, S Severi, A Contestabile, R Bartesaghi, A Contestabile Journal of cell science 117 (20), 4727-4737, 2004 | 93 | 2004 |
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3β/β-catenin signaling S Trazzi, M Steger, VM Mitrugno, R Bartesaghi, E Ciani Journal of Biological Chemistry 285 (13), 10098-10109, 2010 | 92 | 2010 |
Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome A Contestabile, T Fila, R Bartesaghi, E Ciani Brain pathology 19 (2), 224-237, 2009 | 90 | 2009 |
Short-and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome F Stagni, A Giacomini, M Emili, S Trazzi, S Guidi, M Sassi, E Ciani, ... Neuroscience 333, 277-301, 2016 | 87 | 2016 |
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of D own Syndrome S Guidi, F Stagni, P Bianchi, E Ciani, E Ragazzi, S Trazzi, G Grossi, ... Brain pathology 23 (2), 129-143, 2013 | 85 | 2013 |