| Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence E Sapey, H Greenwood, G Walton, E Mann, A Love, N Aaronson, ... Blood, The Journal of the American Society of Hematology 123 (2), 239-248, 2014 | 399 | 2014 |
| Host–microbiota maladaptation in colorectal cancer A Janney, F Powrie, EH Mann Nature 585 (7826), 509-517, 2020 | 343 | 2020 |
| IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies M Friedrich, M Pohin, MA Jackson, I Korsunsky, SJ Bullers, ... Nature medicine 27 (11), 1970-1981, 2021 | 202 | 2021 |
| 1α,25‐dihydroxyvitamin D3 in combination with transforming growth factor‐β increases the frequency of Foxp3+ regulatory T cells through preferential expansion … ES Chambers, D Suwannasaen, EH Mann, Z Urry, DF Richards, ... Immunology 143 (1), 52-60, 2014 | 120 | 2014 |
| A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals P Demetriou, E Abu-Shah, S Valvo, S McCuaig, V Mayya, A Kvalvaag, ... Nature immunology 21 (10), 1232-1243, 2020 | 114 | 2020 |
| Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter PE Pfeffer, H Lu, EH Mann, YH Chen, TR Ho, DJ Cousins, C Corrigan, ... PloS one 13 (8), e0200040, 2018 | 101 | 2018 |
| Immunoregulatory mechanisms of vitamin D relevant to respiratory health and asthma EH Mann, ES Chambers, PE Pfeffer, CM Hawrylowicz Annals of the New York Academy of Sciences 1317 (1), 57-69, 2014 | 85 | 2014 |
| Urban particulate matter–activated human dendritic cells induce the expansion of potent inflammatory Th1, Th2, and Th17 effector cells NC Matthews, PE Pfeffer, EH Mann, FJ Kelly, CJ Corrigan, ... American Journal of Respiratory Cell and Molecular Biology 54 (2), 250-262, 2016 | 68 | 2016 |
| Vitamin D influences asthmatic pathology through its action on diverse immunological pathways PE Pfeffer, EH Mann, E Hornsby, ES Chambers, YH Chen, L Rice, ... Annals of the American Thoracic Society 11 (Supplement 5), S314-S321, 2014 | 46 | 2014 |
| Vitamin D Counteracts an IL-23–Dependent IL-17A+IFN-γ+ Response Driven by Urban Particulate Matter EH Mann, TR Ho, PE Pfeffer, NC Matthews, E Chevretton, I Mudway, ... American journal of respiratory cell and molecular biology 57 (3), 355-366, 2017 | 42 | 2017 |
| Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD 8 T lymphocytes PE Pfeffer, TR Ho, EH Mann, FJ Kelly, M Sehlstedt, J Pourazar, RE Dove, ... Immunology 153 (4), 502-512, 2018 | 37 | 2018 |
| The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer S McCuaig, D Barras, EH Mann, M Friedrich, SJ Bullers, A Janney, ... Clinical Cancer Research 26 (16), 4313-4325, 2020 | 36 | 2020 |
| 1α,25‐dihydroxyvitamin D3 acts via transforming growth factor‐β to up‐regulate expression of immunosuppressive CD73 on human CD4+ Foxp3– T cells EH Mann, ES Chambers, YH Chen, DF Richards, CM Hawrylowicz Immunology 146 (3), 423-431, 2015 | 31 | 2015 |
| MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T-cell responses CE Heuberger, A Janney, N Ilott, A Bertocchi, S Pott, Y Gu, M Pohin, ... Mucosal Immunology 17 (3), 416-430, 2024 | 23 | 2024 |
| High-Dose IL-2 skews a glucocorticoid-driven IL-17+ IL-10+ memory CD4+ T cell response towards a single IL-10–producing phenotype EH Mann, L Gabryšová, PE Pfeffer, A O’Garra, CM Hawrylowicz The Journal of Immunology 202 (3), 684-693, 2019 | 17 | 2019 |
| Biphasic activation of complement and fibrinolysis during the human nasal allergic response RS Thwaites, NC Gunawardana, V Broich, EH Mann, J Ahnström, ... Journal of Allergy and Clinical Immunology 141 (5), 1892-1895. e6, 2018 | 15 | 2018 |
| CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation P Demetriou, E Abu-Shah, S McCuaig, V Mayya, S Valvo, ... Biorxiv, 589440, 2019 | 14 | 2019 |
| miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells T Recaldin, PS Hobson, EH Mann, F Ramadani, DJ Cousins, P Lavender, ... Molecular immunology 101, 419-428, 2018 | 13 | 2018 |
| ASTHMA–comparing the impact of vitamin D versus UVR on clinical and immune parameters KA Morgan, EH Mann, AR Young, CM Hawrylowicz Photochemical & Photobiological Sciences 16 (3), 399-410, 2017 | 12 | 2017 |
| A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice CP Hackstein, D Costigan, L Drexhage, C Pearson, S Bullers, N Ilott, ... Nature communications 13 (1), 7472, 2022 | 11 | 2022 |