MGraphDTA: deep multiscale graph neural network for explainable drug–target binding affinity prediction Z Yang, W Zhong, L Zhao, CYC Chen Chemical science 13 (3), 816-833, 2022 | 209 | 2022 |
ML-DTI: mutual learning mechanism for interpretable drug–target interaction prediction Z Yang, W Zhong, L Zhao, CYC Chen The Journal of Physical Chemistry Letters 12 (17), 4247-4261, 2021 | 77 | 2021 |
Lung lesion localization of COVID-19 from chest CT image: A novel weakly supervised learning method Z Yang, L Zhao, S Wu, CYC Chen IEEE Journal of Biomedical and Health Informatics 25 (6), 1864-1872, 2021 | 59 | 2021 |
Bacillus subtilis spore with surface display of paramyosin from Clonorchis sinensis potentializes a promising oral vaccine candidate H Sun, Z Lin, L Zhao, T Chen, M Shang, H Jiang, Z Tang, X Zhou, M Shi, ... Parasites & Vectors 11, 1-15, 2018 | 51 | 2018 |
Predicting drug–target interactions with deep-embedding learning of graphs and sequences W Chen, G Chen, L Zhao, CYC Chen The Journal of Physical Chemistry A 125 (25), 5633-5642, 2021 | 44 | 2021 |
Clonorchis sinensis granulin: identification, immunolocalization, and function in promoting the metastasis of cholangiocarcinoma and hepatocellular carcinoma C Wang, H Lei, Y Tian, M Shang, Y Wu, Y Li, L Zhao, M Shi, X Tang, ... Parasites & vectors 10, 1-14, 2017 | 36 | 2017 |
Mol2Context-vec: learning molecular representation from context awareness for drug discovery Q Lv, G Chen, L Zhao, W Zhong, C Yu-Chian Chen Briefings in Bioinformatics 22 (6), bbab317, 2021 | 34 | 2021 |
Oral delivery of Bacillus subtilis spores expressing Clonorchis sinensis paramyosin protects grass carp from cercaria infection H Sun, M Shang, Z Tang, H Jiang, H Dong, X Zhou, Z Lin, C Shi, P Ren, ... Applied microbiology and biotechnology 104, 1633-1646, 2020 | 34 | 2020 |
TCMBank-the largest TCM database provides deep learning-based Chinese-Western medicine exclusion prediction Q Lv, G Chen, H He, Z Yang, L Zhao, K Zhang, CYC Chen Signal Transduction and Targeted Therapy 8 (1), 127, 2023 | 32 | 2023 |
CARes‐UNet: Content‐aware residual UNet for lesion segmentation of COVID‐19 from chest CT images X Xu, Y Wen, L Zhao, Y Zhang, Y Zhao, Z Tang, Z Yang, CYC Chen Medical physics 48 (11), 7127-7140, 2021 | 28 | 2021 |
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis L Zhou, M Shi, L Zhao, Z Lin, Z Tang, H Sun, T Chen, Z Lv, J Xu, Y Huang, ... Parasites & vectors 10, 1-10, 2017 | 18 | 2017 |
TCMBank: bridges between the largest herbal medicines, chemical ingredients, target proteins, and associated diseases with intelligence text mining Q Lv, G Chen, H He, Z Yang, L Zhao, HY Chen, CYC Chen Chemical science 14 (39), 10684-10701, 2023 | 17 | 2023 |
Clonorchis sinensis adult-derived proteins elicit Th2 immune responses by regulating dendritic cells via mannose receptor L Zhao, M Shi, L Zhou, H Sun, X Zhang, L He, Z Tang, C Wang, Y Wu, ... PLoS neglected tropical diseases 12 (3), e0006251, 2018 | 17 | 2018 |
A novel graph neural network methodology to investigate dihydroorotate dehydrogenase inhibitors in small cell lung cancer HY Zhi, L Zhao, CC Lee, CYC Chen Biomolecules 11 (3), 477, 2021 | 15 | 2021 |
A novel artificial intelligence protocol to investigate potential leads for Parkinson's disease ZD Chen, L Zhao, HY Chen, JN Gong, X Chen, CYC Chen RSC advances 10 (39), 22939-22958, 2020 | 15 | 2020 |
A novel artificial intelligence protocol to investigate potential leads for diabetes mellitus JN Gong, L Zhao, G Chen, X Chen, ZD Chen, CYC Chen Molecular Diversity 25, 1375-1393, 2021 | 14 | 2021 |
Insight into potent leads for alzheimer's disease by using several artificial intelligence algorithms X He, L Zhao, W Zhong, HY Chen, X Shan, N Tang, CYC Chen Biomedicine & Pharmacotherapy 129, 110360, 2020 | 14 | 2020 |
Csseverin inhibits apoptosis through mitochondria-mediated pathways triggered by Ca2 + dyshomeostasis in hepatocarcinoma PLC cells M Shi, L Zhou, L Zhao, M Shang, T He, Z Tang, H Sun, P Ren, Z Lin, ... PLoS neglected tropical diseases 11 (11), e0006074, 2017 | 14 | 2017 |
Clonorchis sinensis lysophospholipase inhibits TGF-β1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1 … L Zhou, M Shang, M Shi, L Zhao, Z Lin, T Chen, Y Wu, Z Tang, H Sun, ... Parasitology research 115, 643-650, 2016 | 14 | 2016 |
Enhancing adversarial defense for medical image analysis systems with pruning and attention mechanism L Chen, L Zhao, CYC Chen Medical physics 48 (10), 6198-6212, 2021 | 12 | 2021 |