| Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future M Unemo, WM Shafer Clinical microbiology reviews 27 (3), 587-613, 2014 | 1281 | 2014 |
| Degradation of Human Antimicrobial Peptide LL-37 by Staphylococcus aureus-Derived Proteinases M Sieprawska-Lupa, P Mydel, K Krawczyk, K Wójcik, M Puklo, B Lupa, ... Antimicrobial agents and chemotherapy 48 (12), 4673-4679, 2004 | 763 | 2004 |
| Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family WM Shafer, XD Qu, AJ Waring, RI Lehrer Proceedings of the National Academy of Sciences 95 (4), 1829-1833, 1998 | 520 | 1998 |
| Resistance of Neisseria gonorrhoeae to antimicrobial hydrophobic agents is modulated by the mtrRCDE efflux system KE Hagman, W Pan, BG Spratt, JT Balthazar, RC Judd, WM Shafer Microbiology 141 (3), 611-622, 1995 | 481 | 1995 |
| Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future M Unemo, WM Shafer Annals of the New York Academy of Sciences 1230 (1), E19-E28, 2011 | 325 | 2011 |
| Cationic Antimicrobial Peptide Resistance in Neisseria meningitidis YL Tzeng, KD Ambrose, S Zughaier, X Zhou, YK Miller, WM Shafer, ... Journal of bacteriology 187 (15), 5387-5396, 2005 | 321 | 2005 |
| Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate WM Shafer, LE Martin, JK Spitznagel Infection and immunity 45 (1), 29-35, 1984 | 282 | 1984 |
| Antimicrobial Resistance Expressed by Neisseria gonorrhoeae: A Major Global Public Health Problem in the 21st Century M Unemo, CD Rio, WM Shafer Emerging Infections 10, 213-237, 2016 | 277 | 2016 |
| Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC‐MtrD‐MtrE Efflux pump system confer different levels of antimicrobial resistance and … DM Warner, WM Shafer, AE Jerse Molecular microbiology 70 (2), 462-478, 2008 | 257 | 2008 |
| A gonococcal efflux pump system enhances bacterial survival in a female mouse model of genital tract infection AE Jerse, ND Sharma, AN Simms, ET Crow, LA Snyder, WM Shafer Infection and immunity 71 (10), 5576-5582, 2003 | 250 | 2003 |
| Transcriptional control of the mtr efflux system of Neisseria gonorrhoeae KE Hagman, WM Shafer Journal of bacteriology 177 (14), 4162-4165, 1995 | 238 | 1995 |
| Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae WL Veal, RA Nicholas, WM Shafer Journal of bacteriology 184 (20), 5619-5624, 2002 | 233 | 2002 |
| The farAB‐encoded efflux pump mediates resistance of gonococci to long‐chained antibacterial fatty acids EH Lee, WM Shafer Molecular microbiology 33 (4), 839-845, 1999 | 205 | 1999 |
| CAP37, a human neutrophil-derived chemotactic factor with monocyte specific activity. HA Pereira, WM Shafer, J Pohl, LE Martin, JK Spitznagel The Journal of clinical investigation 85 (5), 1468-1476, 1990 | 202 | 1990 |
| Neisseria gonorrhoeae: Drug Resistance, Mouse Models, and Vaccine Development PA Rice, WM Shafer, S Ram, AE Jerse Annual review of microbiology 71 (1), 665-686, 2017 | 198 | 2017 |
| Decreased Azithromycin Susceptibility ofNeisseria gonorrhoeae Due to mtrRMutations L Zarantonelli, G Borthagaray, EH Lee, WM Shafer Antimicrobial agents and chemotherapy 43 (10), 2468-2472, 1999 | 195 | 1999 |
| The NorM Efflux Pump of Neisseria gonorrhoeae and Neisseria meningitidis Recognizes Antimicrobial Cationic Compounds C Rouquette-Loughlin, SA Dunham, M Kuhn, JT Balthazar, WM Shafer Journal of bacteriology 185 (3), 1101-1106, 2003 | 187 | 2003 |
| Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines E Alirol, TE Wi, M Bala, ML Bazzo, XS Chen, C Deal, JAR Dillon, ... PLoS medicine 14 (7), e1002366, 2017 | 178 | 2017 |
| Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids WM Shafer, JT Balthazar, KE Hagman, SA Morse Microbiology 141 (4), 907-911, 1995 | 173 | 1995 |
| The MtrD protein of Neisseria gonorrhoeae is a member of the resistance/nodulation/division protein family constituting part of an efflux system KE Hagman, CE Lucas, JT Balthazar, L Snyder, M Nilles, RC Judd, ... Microbiology 143 (7), 2117-2125, 1997 | 168 | 1997 |
