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| DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 V Tarallo, Y Hirano, BD Gelfand, S Dridi, N Kerur, Y Kim, WG Cho, ... Cell 149 (4), 847-859, 2012 | 675 | 2012 |
| cGAS drives noncanonical-inflammasome activation in age-related macular degeneration N Kerur, S Fukuda, D Banerjee, Y Kim, D Fu, I Apicella, A Varshney, ... Nature medicine 24 (1), 50-61, 2018 | 252 | 2018 |
| Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity BJ Fowler, BD Gelfand, Y Kim, N Kerur, V Tarallo, Y Hirano, S Amarnath, ... Science 346 (6212), 1000-1003, 2014 | 244 | 2014 |
| TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy N Kerur, Y Hirano, V Tarallo, BJ Fowler, A Bastos-Carvalho, T Yasuma, ... Investigative ophthalmology & visual science 54 (12), 7395-7401, 2013 | 189 | 2013 |
| ERK1/2 activation is a therapeutic target in age-related macular degeneration S Dridi, Y Hirano, V Tarallo, Y Kim, BJ Fowler, BK Ambati, S Bogdanovich, ... Proceedings of the National Academy of Sciences 109 (34), 13781-13786, 2012 | 119 | 2012 |
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| DICER1/Alu RNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration Y Kim, V Tarallo, N Kerur, T Yasuma, BD Gelfand, A Bastos-Carvalho, ... Proceedings of the National Academy of Sciences 111 (45), 16082-16087, 2014 | 106 | 2014 |
| Iron toxicity in the retina requires Alu RNA and the NLRP3 inflammasome BD Gelfand, CB Wright, Y Kim, T Yasuma, R Yasuma, S Li, BJ Fowler, ... Cell reports 11 (11), 1686-1693, 2015 | 101 | 2015 |
| Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration S Fukuda, A Varshney, BJ Fowler, S Wang, S Narendran, K Ambati, ... Proceedings of the National Academy of Sciences 118 (6), e2022751118, 2021 | 53 | 2021 |
| Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development J Ambati, J Magagnoli, H Leung, S Wang, CA Andrews, D Fu, A Pandey, ... Nature communications 11 (1), 4737, 2020 | 50 | 2020 |
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| Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice CB Wright, H Uehara, Y Kim, T Yasuma, R Yasuma, S Hirahara, ... Proceedings of the National Academy of Sciences 117 (5), 2579-2587, 2020 | 37 | 2020 |
| Nucleoside reverse transcriptase inhibitors suppress laser-induced choroidal neovascularization in mice T Mizutani, BJ Fowler, Y Kim, R Yasuma, LA Krueger, BD Gelfand, ... Investigative ophthalmology & visual science 56 (12), 7122-7129, 2015 | 37 | 2015 |
| NLRP3 inflammasome activation by mycobacterial ESAT-6 and dsRNA in intraocular tuberculosis S Basu, BJ Fowler, N Kerur, KB Arnvig, NA Rao Microbial pathogenesis 114, 219-224, 2018 | 34 | 2018 |
| Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity S Fukuda, S Narendran, A Varshney, Y Nagasaka, S Wang, K Ambati, ... Science advances 7 (40), eabj3658, 2021 | 33 | 2021 |
| UV-photokeratitis associated with germicidal lamps purchased during the COVID-19 pandemic JD Sengillo, AL Kunkler, C Medert, B Fowler, M Shoji, N Pirakitikulr, ... Ocular immunology and inflammation 29 (1), 76-80, 2021 | 31 | 2021 |
| Intravenous immune globulin suppresses angiogenesis in mice and humans R Yasuma, V Cicatiello, T Mizutani, L Tudisco, Y Kim, V Tarallo, ... Signal transduction and targeted therapy 1 (1), 1-8, 2016 | 29 | 2016 |
