Non‐selective cation channel activity of aquaporin AtPIP2;1 regulated by Ca2+ and pH CS Byrt, M Zhao, M Kourghi, J Bose, SW Henderson, J Qiu, M Gilliham, ... Plant, cell & environment 40 (6), 802-815, 2017 | 201 | 2017 |
Divalent cations regulate the ion conductance properties of diverse classes of aquaporins M Kourghi, S Nourmohammadi, JV Pei, J Qiu, S McGaughey, SD Tyerman, ... International journal of molecular sciences 18 (11), 2323, 2017 | 74 | 2017 |
Bumetanide derivatives AqB007 and AqB011 selectively block the aquaporin-1 ion channel conductance and slow cancer cell migration M Kourghi, JV Pei, ML De Ieso, G Flynn, AJ Yool Molecular pharmacology 89 (1), 133-140, 2016 | 69 | 2016 |
Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant bacopa … JV Pei, M Kourghi, ML De Ieso, EM Campbell, HS Dorward, ... Molecular pharmacology 90 (4), 496-507, 2016 | 66 | 2016 |
Fundamental structural and functional properties of Aquaporin ion channels found across the kingdoms of life M Kourghi, JV Pei, ML De Ieso, S Nourmohammadi, PH Chow, AJ Yool Clinical and Experimental Pharmacology and Physiology 45 (4), 401-409, 2018 | 49 | 2018 |
Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration ML De Ieso, JV Pei, S Nourmohammadi, E Smith, PH Chow, M Kourghi, ... Scientific reports 9 (1), 12635, 2019 | 43 | 2019 |
5-hydroxymethyl-furfural and structurally related compounds block the ion conductance in human aquaporin-1 channels and slow cancer cell migration and invasion PH Chow, M Kourghi, JV Pei, S Nourmohammadi, AJ Yool Molecular Pharmacology 98 (1), 38-48, 2020 | 30 | 2020 |
Identification of loop D domain amino acids in the human Aquaporin-1 channel involved in activation of the ionic conductance and inhibition by AqB011 M Kourghi, ML De Ieso, S Nourmohammadi, JV Pei, AJ Yool Frontiers in chemistry 6, 142, 2018 | 27 | 2018 |
Development of a photoswitchable lithium-sensitive probe to analyze nonselective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, G Sylvia, M Kourghi, S Nourmohammadi, ... Molecular Pharmacology 95 (5), 573-583, 2019 | 23 | 2019 |
Drug discovery and therapeutic targets for pharmacological modulators of aquaporin channels JV Pei, JL Burton, M Kourghi, ML De Ieso, AJ Yool Aquaporins in Health and Disease: New Molecular Targets For Drug Discovery …, 2016 | 9 | 2016 |
Lithium ‘Hot-spots’: Real-time Analysis of non-selective cation channel activity in migrating cancer cells JV Pei, S Heng, ML De Ieso, GM Sylvia, M Kourghi Mol Pharmacol 10, 2019 | 2 | 2019 |
De leso ML, Nourmohammadi S, Pei JV and Yool AJ (2018) Identification of Loop D Domain Amino Acids in the Human Aquaporin-1 Channel Involved in Activation of the lonic … M Kourghi Membrane Transporters and Channels as Targets for Drugs, 142126, 2020 | | 2020 |
Real-Time Imaging of Lithium ‘Hot-Spots’: An Analysis of Ion Conductance in Aquaporin-1 using Novel Photo-Switchable Sensor JV Pei, S Heng, M De Ieso, G Sylvia, M Kourghi, AD Abell, AJ Yool Biophysical Journal 114 (3), 360a, 2018 | | 2018 |
Drug Discovery and Therapeutic Targets for Pharmacological Modulators of Aquaporin Channels AJY Jinxin Victor Pei, Joshua Luke Burton, Mohamad Kourghi, Michael L De Ieso Aquaporins in Health and Disease: New Molecular Targets for Drug Discovery 1, 2015 | | 2015 |