Theo dõi
Clemens Schmitt
Clemens Schmitt
Universitätsprofessor und Vorstand Universitätsklinik für Hämatologie und Internistische Onkologie, Kepler Universitätsklinikum, Johannes Kepler Universität, Linz
Email được xác minh tại kepleruniklinikum.at
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Cellular senescence: defining a path forward
V Gorgoulis, PD Adams, A Alimonti, DC Bennett, O Bischof, C Bishop, ...
Cell 179 (4), 813-827, 2019
23912019
Oncogene-induced senescence as an initial barrier in lymphoma development
M Braig, S Lee, C Loddenkemper, C Rudolph, AHFM Peters, ...
Nature 436 (7051), 660-665, 2005
14852005
A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
CA Schmitt, JS Fridman, M Yang, S Lee, E Baranov, RM Hoffman, ...
Cell 109 (3), 335-346, 2002
12722002
Senescence-associated reprogramming promotes cancer stemness
M Milanovic, DNY Fan, D Belenki, JHM Däbritz, Z Zhao, Y Yu, JR Dörr, ...
Nature 553 (7686), 96-100, 2018
10192018
Dissecting p53 tumor suppressor functions in vivo
CA Schmitt, JS Fridman, M Yang, E Baranov, RM Hoffman, SW Lowe
Cancer cell 1 (3), 289-298, 2002
6172002
Synthetic lethal metabolic targeting of cellular senescence in cancer therapy
JR Dörr, Y Yu, M Milanovic, G Beuster, C Zasada, JHM Däbritz, J Lisec, ...
Nature 501 (7467), 421-425, 2013
6112013
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53
MJ Bywater, G Poortinga, E Sanij, N Hein, A Peck, C Cullinane, M Wall, ...
Cancer cell 22 (1), 51-65, 2012
6082012
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
CA Schmitt, ME McCurrach, E de Stanchina, RR Wallace-Brodeur, ...
Genes & development 13 (20), 2670-2677, 1999
5901999
The dynamic nature of senescence in cancer
S Lee, CA Schmitt
Nature cell biology 21 (1), 94-101, 2019
5862019
Apoptosis and therapy
CA Schmitt, SW Lowe
The Journal of pathology 187 (1), 127-137, 1999
4531999
Senescence, apoptosis and therapy—cutting the lifelines of cancer
CA Schmitt
Nature Reviews Cancer 3 (4), 286-295, 2003
4232003
Oncogene-induced senescence: putting the brakes on tumor development
M Braig, CA Schmitt
Cancer research 66 (6), 2881-2884, 2006
3642006
Cellular senescence and cancer treatment
CA Schmitt
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1775 (1), 5-20, 2007
3432007
Genetic analysis of chemoresistance in primary murine lymphomas
CA Schmitt, CT Rosenthal, SW Lowe
Nature medicine 6 (9), 1029-1035, 2000
3412000
Therapy-induced senescence: opportunities to improve anticancer therapy
PG Prasanna, DE Citrin, J Hildesheim, MM Ahmed, S Venkatachalam, ...
JNCI: Journal of the National Cancer Institute 113 (10), 1285-1298, 2021
2552021
Tumor stroma-derived TGF-β limits myc-driven lymphomagenesis via Suv39h1-dependent senescence
M Reimann, S Lee, C Loddenkemper, JR Dörr, V Tabor, P Aichele, ...
Cancer cell 17 (3), 262-272, 2010
2222010
Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis
CM Arends, J Galan-Sousa, K Hoyer, W Chan, M Jäger, K Yoshida, ...
Leukemia 32 (9), 1908-1919, 2018
1942018
AP-1 imprints a reversible transcriptional programme of senescent cells
RI Martínez-Zamudio, PF Roux, JANLF de Freitas, L Robinson, G Doré, ...
Nature cell biology 22 (7), 842-855, 2020
1702020
Hypoxia-inducible factor 1α determines gastric cancer chemosensitivity via modulation of p53 and NF-κB
N Rohwer, C Dame, A Haugstetter, B Wiedenmann, K Detjen, CA Schmitt, ...
PloS one 5 (8), e12038, 2010
1692010
Targeting the senescence-overriding cooperative activity of structurally unrelated H3K9 demethylases in melanoma
Y Yu, K Schleich, B Yue, S Ji, P Lohneis, K Kemper, MR Silvis, N Qutob, ...
Cancer cell 33 (2), 322-336. e8, 2018
1682018
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