Theo dõi
Grégoire Philippe
Grégoire Philippe
PhD in biochemistry and cellular biology
Email được xác minh tại g.ecc.u-tokyo.ac.jp
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Converting peptides into drugs targeting intracellular protein–protein interactions
GJB Philippe, DJ Craik, ST Henriques
Drug Discovery Today 26 (6), 1521-1531, 2021
822021
Development of cell‐penetrating peptide‐based drug leads to inhibit MDMX: p53 and MDM2: p53 interactions
G Philippe, YH Huang, O Cheneval, N Lawrence, Z Zhang, DP Fairlie, ...
Peptide Science 106 (6), 853-863, 2016
282016
Angler peptides: macrocyclic conjugates inhibit p53: MDM2/X interactions and activate apoptosis in cancer cells
GJB Philippe, A Mittermeier, N Lawrence, YH Huang, ND Condon, ...
ACS chemical biology 16 (2), 414-428, 2021
242021
Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells
N Lawrence, GJB Philippe, PJ Harvey, ND Condon, AH Benfield, ...
RSC Chemical Biology 1 (5), 405-420, 2020
202020
Cell membrane composition drives selectivity and toxicity of designed cyclic helix–loop–helix peptides with cell penetrating and tumor suppressor properties
GJB Philippe, D Gaspar, C Sheng, YH Huang, AH Benfield, ND Condon, ...
ACS Chemical Biology 14 (9), 2071-2087, 2019
202019
Delivery to, and reactivation of, the p53 pathway in cancer cells using a grafted cyclotide conjugated with a cell-penetrating peptide
GJB Philippe, YH Huang, A Mittermeier, CJ Brown, Q Kaas, SR Ramlan, ...
Journal of medicinal chemistry 67 (2), 1197-1208, 2024
102024
Activating the p53 pathway with peptide conjugates: synthesis, structure, activity and cellular uptake
G Philippe, YH Huang, A Mittermeier, C Brown, C Wang, Q Kaas, ...
Journal of Peptide Science 28, 2022
2022
Development of peptide-based anti-cancer drugs targeting intracellular protein-protein interactions
GJB Philippe
2020
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