| Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1285 | 2015 |
| c-Jun overexpression in CAR T cells induces exhaustion resistance RC Lynn, EW Weber, E Sotillo, D Gennert, P Xu, Z Good, H Anbunathan, ... Nature 576 (7786), 293-300, 2019 | 722 | 2019 |
| CAR T cells targeting B7-H3, a pan-cancer antigen, demonstrate potent preclinical activity against pediatric solid tumors and brain tumors RG Majzner, JL Theruvath, A Nellan, S Heitzeneder, Y Cui, CW Mount, ... Clinical Cancer Research 25 (8), 2560-2574, 2019 | 561 | 2019 |
| Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 485 | 2021 |
| Tuning the antigen density requirement for CAR T-cell activity RG Majzner, SP Rietberg, E Sotillo, R Dong, VT Vachharajani, ... Cancer discovery 10 (5), 702-723, 2020 | 451 | 2020 |
| Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors J Theruvath, E Sotillo, CW Mount, CM Graef, A Delaidelli, S Heitzeneder, ... Nature medicine 26 (5), 712-719, 2020 | 245 | 2020 |
| Pharmacologic control of CAR-T cell function using dasatinib EW Weber, RC Lynn, E Sotillo, J Lattin, P Xu, CL Mackall Blood advances 3 (5), 711-717, 2019 | 226 | 2019 |
| Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy. Cancer Discov. 2015; 5 (12): 1282–95. doi: 10.1158/2159-8290 E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... CD-15-1020. For the first time here, a mechanism of antigen-loss escape …, 0 | 189 | |
| Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication J Theruvath, M Menard, BAH Smith, MH Linde, GL Coles, GN Dalton, ... Nature medicine 28 (2), 333-344, 2022 | 172 | 2022 |
| CAR T cell therapy for neuroblastoma RM Richards, E Sotillo, RG Majzner Frontiers in immunology 9, 2380, 2018 | 164 | 2018 |
| Enhanced safety and efficacy of protease-regulated CAR-T cell receptors L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ... Cell 185 (10), 1745-1763. e22, 2022 | 158 | 2022 |
| Co-opting signalling molecules enables logic-gated control of CAR T cells AM Tousley, MC Rotiroti, L Labanieh, LW Rysavy, WJ Kim, C Lareau, ... Nature 615 (7952), 507-516, 2023 | 155 | 2023 |
| Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells DB Rivadeneira, CN Mayhew, C Thangavel, E Sotillo, CA Reed, X Graña, ... Gastroenterology 138 (5), 1920-1930. e2, 2010 | 151 | 2010 |
| GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity S Heitzeneder, KR Bosse, Z Zhu, D Zhelev, RG Majzner, MT Radosevich, ... Cancer Cell 40 (1), 53-69. e9, 2022 | 129 | 2022 |
| G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression J Calbó, M Parreño, E Sotillo, T Yong, A Mazo, J Garriga, X Grana Journal of Biological Chemistry 277 (52), 50263-50274, 2002 | 116 | 2002 |
| Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma H Yu, E Sotillo, C Harrington, G Wertheim, M Paessler, SL Maude, ... American journal of hematology 92 (1), E11, 2016 | 112 | 2016 |
| Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery SH Chiou, D Tseng, A Reuben, V Mallajosyula, IS Molina, S Conley, ... Immunity 54 (3), 586-602. e8, 2021 | 109 | 2021 |
| Myc overexpression brings out unexpected antiapoptotic effects of miR-34a E Sotillo, T Laver, H Mellert, JM Schelter, MA Cleary, S McMahon, ... Oncogene 30 (22), 2587-2594, 2011 | 103 | 2011 |
| Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19 M Asnani, KE Hayer, AS Naqvi, S Zheng, SY Yang, D Oldridge, F Ibrahim, ... Leukemia 34 (4), 1202-1207, 2020 | 90 | 2020 |
| Enhanced T cell effector activity by targeting the Mediator kinase module KA Freitas, JA Belk, E Sotillo, PJ Quinn, MC Ramello, M Malipatlolla, ... Science 378 (6620), eabn5647, 2022 | 77 | 2022 |
Crystal MackallStanford UniversityEmail được xác minh tại stanford.edu