Neoadjuvant pembrolizumab in localized microsatellite instability high/deficient mismatch repair solid tumors K Ludford, WJ Ho, JV Thomas, KPS Raghav, MB Murphy, ND Fleming, ... Journal of Clinical Oncology 41 (12), 2181-2190, 2023 | 118 | 2023 |
Profiling of syngeneic mouse HCC tumor models as a framework to understand anti–PD‐1 sensitive tumor microenvironments DJ Zabransky, L Danilova, JM Leatherman, TY Lopez‐Vidal, J Sanchez, ... Hepatology 77 (5), 1566-1579, 2023 | 39 | 2023 |
PanIN and CAF transitions in pancreatic carcinogenesis revealed with spatial data integration ATF Bell, JT Mitchell, AL Kiemen, M Lyman, K Fujikura, JW Lee, E Coyne, ... Cell Systems 15 (8), 753-769. e5, 2024 | 15 | 2024 |
Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial ET Roussos Torres, WJ Ho, L Danilova, JA Tandurella, J Leatherman, ... Nature Cancer, 1-14, 2024 | 11 | 2024 |
Reprogramming the Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti–PD-1 Therapy J Chen, Z Amoozgar, X Liu, S Aoki, Z Liu, SM Shin, A Matsui, ... Cancer Immunology Research 12 (4), 400-412, 2024 | 9 | 2024 |
Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade DH Shu, WJ Ho, LT Kagohara, A Girgis, SM Shin, L Danilova, JW Lee, ... bioRxiv, 2023 | 8 | 2023 |
Multimodal immune phenotyping reveals microbial-T cell interactions that shape pancreatic cancer Y Li, RB Chang, ML Stone, D Delman, K Markowitz, Y Xue, H Coho, ... Cell Reports Medicine 5 (2), 2024 | 7 | 2024 |
Immunotherapy response induces divergent tertiary lymphoid structure morphologies in hepatocellular carcinoma DH Shu, WJ Ho, LT Kagohara, A Girgis, SM Shin, L Danilova, JW Lee, ... Nature Immunology, 1-14, 2024 | 6 | 2024 |
Combination of CXCR4 antagonist and anti-PD1 therapy results in significant mobilization and increased infiltration of myeloid cells into the metastatic liver microenvironment … SM Shin, A Hernandez, E Coyne, Z Zhang, S Mitchell, J Durham, X Yuan, ... Cancer Research 83 (7_Supplement), 2270-2270, 2023 | 4 | 2023 |
CyTOF protocol for immune monitoring of solid tumors from mouse models SM Shin, A Hernandez, E Coyne, K Munjal, NE Gross, S Charmsaz, ... STAR protocols 4 (1), 101949, 2023 | 4 | 2023 |
Immune-related events in individuals with solid tumors on immunotherapy associate with Th17 and Th2 signatures CJ Kao, S Charmsaz, SL Alden, M Brancati, HL Li, A Balaji, K Munjal, ... The Journal of Clinical Investigation 134 (20), 2024 | 3 | 2024 |
Spatial mass cytometry-based single cell imaging reveals a disrupted epithelial-immune axis in prurigo nodularis J Patel, J Deng, A Kambala, KK Lee, HL Cornman, V Parthasarathy, ... Journal of Investigative Dermatology, 2024 | 3 | 2024 |
Phosphodiesterase-5 inhibition collaborates with vaccine-based immunotherapy to reprogram myeloid cells in pancreatic ductal adenocarcinoma NE Gross, Z Zhang, JT Mitchell, S Charmsaz, AG Hernandez, EM Coyne, ... JCI insight 9 (18), e179292, 2024 | 1 | 2024 |
Preventing NK cell activation in the damaged liver induced by cabozantinib/PD-1 blockade increases survival in hepatocellular carcinoma models S Morita, H Kikuchi, G Birch, A Matsui, A Morita, T Kobayashi, Z Ruan, ... bioRxiv, 2023.10. 20.563378, 2023 | 1 | 2023 |
Reprogramming Intrahepatic Cholangiocarcinoma Immune Microenvironment by Chemotherapy and CTLA-4 Blockade Enhances Anti-PD1 Therapy J Chen, Z Amoozgar, X Liu, S Aoki, Z Liu, S Shin, A Matsui, Z Pu, PJ Lei, ... bioRxiv, 2023 | 1 | 2023 |
Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression S Guinn, B Perez, JA Tandurella, M Ramani, JW Lee, DJ Zabransky, ... bioRxiv, 2025 | | 2025 |
209 Spatial multi-omics reveal humoral immunity niches associated with tertiary lymphoid structures in pancreatic cancer pathologic responders to neoadjuvant immunotherapy DN Sidiropoulos, SM Shin, A Girgis, M Wetzel, DH Shu, J Montagne, ... Journal for ImmunoTherapy of Cancer 12 (Suppl 2), 2024 | | 2024 |
Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells EM Grasset, A Deshpande, JW Lee, Y Cho, SM Shin, EM Coyne, ... Oncogene 43 (39), 2927-2937, 2024 | | 2024 |
Abstract PR-08: Reprogramming and selective recruitment of distinct neutrophil subpopulations restrain cancer metastasis JW Lee, DC Vargas Carvajal, Y Cho, SM Shin, EM Coyne, A Hernandez, ... Cancer Research 84 (17_Supplement_2), PR-08-PR-08, 2024 | | 2024 |
Abstract A032: Cancer associated fibroblasts drive classical to basal change associated with increased T cell presence in pancreatic ductal adenocarcinoma JW Zimmerman, S Guinn, M Ramani, B Perez, JA Tandurella, ... Cancer Research 84 (17_Supplement_2), A032-A032, 2024 | | 2024 |