| Insights into sex chromosome evolution and aging from the genome of a short-lived fish K Reichwald, A Petzold, P Koch, BR Downie, N Hartmann, S Pietsch, ... Cell 163 (6), 1527-1538, 2015 | 311 | 2015 |
| Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors BR Downie, A Sánchez, H Knötgen, C Contreras-Jurado, ... Journal of Biological Chemistry 283 (52), 36234-36240, 2008 | 200 | 2008 |
| Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference C Weber, FM de Queiroz, BR Downie, A Suckow, W Stuhmer, LA Pardo Journal of Biological Chemistry 281 (19), 13030-13037, 2006 | 141 | 2006 |
| RepARK—de novo creation of repeat libraries from whole-genome NGS reads P Koch, M Platzer, BR Downie Nucleic acids research 42 (9), e80-e80, 2014 | 96 | 2014 |
| Sensing cardiac electrical activity with a cardiac myocyte–targeted optogenetic voltage indicator ML Chang Liao, TP de Boer, H Mutoh, N Raad, C Richter, E Wagner, ... Circulation research 117 (5), 401-412, 2015 | 74 | 2015 |
| Genomic modeling of hepatitis B virus integration frequency in the human genome O Podlaha, G Wu, B Downie, R Ramamurthy, A Gaggar, M Subramanian, ... PloS one 14 (7), e0220376, 2019 | 51 | 2019 |
| Filgotinib or lanraplenib in moderate to severe cutaneous lupus erythematosus: a phase 2, randomized, double-blind, placebo-controlled study VP Werth, R Fleischmann, M Robern, Z Touma, I Tiamiyu, O Gurtovaya, ... Rheumatology 61 (6), 2413-2423, 2022 | 50 | 2022 |
| Safety and efficacy of filgotinib, lanraplenib and tirabrutinib in Sjögren’s syndrome: a randomized, phase 2, double-blind, placebo-controlled study E Price, M Bombardieri, A Kivitz, F Matzkies, O Gurtovaya, A Pechonkina, ... Rheumatology 61 (12), 4797-4808, 2022 | 43 | 2022 |
| The DNA methyltransferase 1 (DNMT1) controls the shape and dynamics of migrating POA-derived interneurons fated for the murine cerebral cortex D Pensold, J Symmank, A Hahn, T Lingner, G Salinas-Riester, ... Cerebral Cortex 27 (12), 5696-5714, 2017 | 41 | 2017 |
| Approaches targeting Kv10. 1 open a novel window for cancer diagnosis and therapy LA Pardo, D Gomez-Varela, F Major, K Sansuk, R Leurs, BR Downie, ... Current medicinal chemistry 19 (5), 675-682, 2012 | 36 | 2012 |
| Blocking viral entry with bulevirtide reduces the number of HDV-infected hepatocytes in human liver biopsies L Allweiss, A Volmari, V Suri, JJ Wallin, JF Flaherty, D Manuilov, ... Journal of Hepatology 80 (6), 882-891, 2024 | 19 | 2024 |
| The Redox Homeostasis of Skeletal Muscle Cells Regulates Stage Differentiation of Toxoplasma gondii MT Rahman, IJ Swierzy, B Downie, G Salinas, M Blume, MJ McConville, ... Frontiers in cellular and infection microbiology 11, 798549, 2021 | 8 | 2021 |
| Histone deacetylase inhibitor MS-275 augments expression of a subset of IFN-γ-regulated genes in Toxoplasma gondii-infected macrophages but does not improve parasite control K Sumpf, R Nast, B Downie, G Salinas, CGK Lüder Experimental Parasitology 180, 45-54, 2017 | 7 | 2017 |
| Remdesivir improves biomarkers associated with disease severity in COVID-19 patients treated in an outpatient setting DZ Pan, PM Odorizzi, A Schoenichen, M Abdelghany, S Chen, A Osinusi, ... Communications Medicine 3 (1), 2, 2023 | 5 | 2023 |
| POS0536 filgotinib demonstrates clinical efficacy in rheumatoid arthritis independent of smoking status: a post-hoc subgroup analysis of three phase 3 clinical trials P Emery, B Downie, J Liu, R Hawtin, JR Curtis, GR Burmester Annals of the Rheumatic Diseases 80, 502, 2021 | 3 | 2021 |
| Changes to inflammatory markers during 5 years of viral suppression and during viral blips in people with HIV initiating different integrase inhibitor based regimens NT Funderburg, SSY Huang, C Cohen, K Ailstock, M Cummings, JC Lee, ... Frontiers in immunology 15, 1488799, 2024 | 2 | 2024 |
| Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironment in patients with chronic hepatitis B DZ Pan, CM Soulette, A Aggarwal, D Han, N van Buuren, P Wu, ... Gut, 2024 | 2 | 2024 |
| Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis JR Curtis, P Emery, B Downie, Y Zhong, J Liu, L Han, RE Hawtin, ... Rheumatology and Therapy 11 (1), 177-189, 2024 | 2 | 2024 |
| Filgotinib modulates inflammation-associated peripheral blood protein biomarkers in adults with active rheumatoid arthritis and prior inadequate response to methotrexate Y Tanaka, PC Taylor, E Elboudwarej, A Hertz, X Shao, VA Malkov, ... Rheumatology and Therapy 10 (5), 1335-1348, 2023 | 2 | 2023 |
| THU0215 WHOLE BLOOD TRANSCRIPTIONAL CHANGES FOLLOWING SELECTIVE INHIBITION OF JANUS KINASE 1 (JAK1) BY FILGOTINIB IN ADULTS WITH MODERATELY-TO-SEVERELY ACTIVE RHEUMATOID … PC Taylor, B Downie, E Elboudwarej, S Kim, A Hertz, AM Mirza, J Siegel, ... Annals of the Rheumatic Diseases 79, 333, 2020 | 2* | 2020 |
Luis PardoGroup Leader, Max-Planck Institute of Experimental MedicineEmail được xác minh tại em.mpg.de