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| Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials Y Cheng, C He, M Wang, X Ma, F Mo, S Yang, J Han, X Wei Signal transduction and targeted therapy 4 (1), 62, 2019 | 1000 | 2019 |
| Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication J Han, H Zhou, B Horazdovsky, K Zhang, RM Xu, Z Zhang Science 315 (5812), 653-655, 2007 | 479 | 2007 |
| Acetylation of lysine 56 of histone H3 catalyzed by RTT109 and regulated by ASF1 is required for replisome integrity J Han, H Zhou, Z Li, RM Xu, Z Zhang Journal of Biological Chemistry 282 (39), 28587-28596, 2007 | 218 | 2007 |
| Strand-specific analysis shows protein binding at replication forks and PCNA unloading from lagging strands when forks stall C Yu, H Gan, J Han, ZX Zhou, S Jia, A Chabes, G Farrugia, T Ordog, ... Molecular cell 56 (4), 551-563, 2014 | 207 | 2014 |
| A role for Gcn5 in replication-coupled nucleosome assembly RJ Burgess, H Zhou, J Han, Z Zhang Molecular cell 37 (4), 469-480, 2010 | 183 | 2010 |
| A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly J Han, H Zhang, H Zhang, Z Wang, H Zhou, Z Zhang Cell 155 (4), 817-829, 2013 | 153 | 2013 |
| The Rtt109-Vps75 histone acetyltransferase complex acetylates non-nucleosomal histone H3 J Han, H Zhou, Z Li, RM Xu, Z Zhang Journal of Biological Chemistry 282 (19), 14158-14164, 2007 | 125 | 2007 |
| Involvement of a chromatin remodeling complex in damage tolerance during DNA replication KB Falbo, C Alabert, Y Katou, S Wu, J Han, T Wehr, J Xiao, X He, Z Zhang, ... Nature structural & molecular biology 16 (11), 1167-1172, 2009 | 98 | 2009 |
| Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication J Han, Q Li, L McCullough, C Kettelkamp, T Formosa, Z Zhang Genes & development 24 (14), 1485-1490, 2010 | 85 | 2010 |
| KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming F Na, X Pan, J Chen, X Chen, M Wang, P Chi, L You, L Zhang, A Zhong, ... Nature cancer 3 (6), 753-767, 2022 | 73 | 2022 |
| Hepatocyte growth factor induces redistribution of p21CIP1 and p27KIP1 through ERK-dependent p16INK4a up-regulation, leading to cell cycle arrest at G1 in HepG2 hepatoma cells J Han, Y Tsukada, E Hara, N Kitamura, T Tanaka Journal of Biological Chemistry 280 (36), 31548-31556, 2005 | 71 | 2005 |
| Checkpoint kinase Rad53 couples leading-and lagging-strand DNA synthesis under replication stress H Gan, C Yu, S Devbhandari, S Sharma, J Han, A Chabes, D Remus, ... Molecular cell 68 (2), 446-455. e3, 2017 | 66 | 2017 |
| RNA modification: mechanisms and therapeutic targets L Qiu, Q Jing, Y Li, J Han Molecular biomedicine 4 (1), 25, 2023 | 62 | 2023 |
| The key role of exosomes on the pre-metastatic niche formation in tumors X Yang, Y Zhang, Y Zhang, S Zhang, L Qiu, Z Zhuang, M Wei, X Deng, ... Frontiers in molecular biosciences 8, 703640, 2021 | 57 | 2021 |
| A DNA binding winged helix domain in CAF-1 functions with PCNA to stabilize CAF-1 at replication forks K Zhang, Y Gao, J Li, R Burgess, J Han, H Liang, Z Zhang, Y Liu Nucleic acids research 44 (11), 5083-5094, 2016 | 57 | 2016 |
| Repurposing brigatinib for the treatment of colorectal cancer based on inhibition of ER-phagy Z Zhang, W Gao, LI Zhou, Y Chen, S Qin, LU Zhang, J Liu, Y He, Y Lei, ... Theranostics 9 (17), 4878, 2019 | 55 | 2019 |
| Human histone acetyltransferase 1 protein preferentially acetylates H4 histone molecules in H3. 1-H4 over H3. 3-H4 H Zhang, J Han, B Kang, R Burgess, Z Zhang Journal of Biological Chemistry 287 (9), 6573-6581, 2012 | 50 | 2012 |
| Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy Y Meng, L Qiu, X Zeng, X Hu, Y Zhang, X Wan, X Mao, J Wu, Y Xu, ... Signal Transduction and Targeted Therapy 7 (1), 388, 2022 | 45 | 2022 |
| Cul4 E3 ubiquitin ligase regulates ovarian cancer drug resistance by targeting the antiapoptotic protein BIRC3 X Hu, Y Meng, L Xu, L Qiu, M Wei, D Su, X Qi, Z Wang, S Yang, C Liu, ... Cell death & disease 10 (2), 104, 2019 | 43 | 2019 |
