The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide S Viaud, F Saccheri, G Mignot, T Yamazaki, R Daillère, D Hannani, ... science 342 (6161), 971-976, 2013 | 2130 | 2013 |
Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species R Zilionis, C Engblom, C Pfirschke, V Savova, D Zemmour, HD Saatcioglu, ... Immunity 50 (5), 1317-1334. e10, 2019 | 1262 | 2019 |
Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy A Sistigu, T Yamazaki, E Vacchelli, K Chaba, DP Enot, J Adam, I Vitale, ... Nature medicine 20 (11), 1301-1309, 2014 | 1124 | 2014 |
Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy C Pfirschke, C Engblom, S Rickelt, V Cortez-Retamozo, C Garris, F Pucci, ... Immunity 44 (2), 343-354, 2016 | 969 | 2016 |
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 916 | 2018 |
The role of myeloid cells in cancer therapies C Engblom, C Pfirschke, MJ Pittet Nature Reviews Cancer 16 (7), 447-462, 2016 | 782 | 2016 |
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt (IV) pro-drug MA Miller, YR Zheng, S Gadde, C Pfirschke, H Zope, C Engblom, ... Nature communications 6 (1), 8692, 2015 | 463 | 2015 |
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils C Engblom, C Pfirschke, R Zilionis, J Da Silva Martins, SA Bos, G Courties, ... Science 358 (6367), eaal5081, 2017 | 363 | 2017 |
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle MA Miller, S Gadde, C Pfirschke, C Engblom, MM Sprachman, RH Kohler, ... Science translational medicine 7 (314), 314ra183-314ra183, 2015 | 358 | 2015 |
SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions F Pucci, C Garris, CP Lai, A Newton, C Pfirschke, C Engblom, D Alvarez, ... Science 352 (6282), 242-246, 2016 | 343 | 2016 |
Crizotinib-induced immunogenic cell death in non-small cell lung cancer P Liu, L Zhao, J Pol, S Levesque, A Petrazzuolo, C Pfirschke, C Engblom, ... Nature communications 10 (1), 1486, 2019 | 269 | 2019 |
Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions A Andersson, L Larsson, L Stenbeck, F Salmén, A Ehinger, SZ Wu, ... Nature communications 12 (1), 6012, 2021 | 262 | 2021 |
Durable and controlled depletion of neutrophils in mice G Boivin, J Faget, PB Ancey, A Gkasti, J Mussard, C Engblom, C Pfirschke, ... Nature communications 11 (1), 2762, 2020 | 252 | 2020 |
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts MA Miller, R Chandra, MF Cuccarese, C Pfirschke, C Engblom, ... Science translational medicine 9 (392), eaal0225, 2017 | 227 | 2017 |
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging MF Cuccarese, JM Dubach, C Pfirschke, C Engblom, C Garris, MA Miller, ... Nature communications 8 (1), 14293, 2017 | 180 | 2017 |
TLR2/MyD88-dependent and-independent activation of mast cell IgE responses by the skin commensal yeast Malassezia sympodialis C Selander, C Engblom, G Nilsson, A Scheynius, CL Andersson The Journal of Immunology 182 (7), 4208-4216, 2009 | 111 | 2009 |
PF4 promotes platelet production and lung cancer growth F Pucci, S Rickelt, AP Newton, C Garris, E Nunes, C Evavold, C Pfirschke, ... Cell reports 17 (7), 1764-1772, 2016 | 110 | 2016 |
Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils C Pfirschke, C Engblom, J Gungabeesoon, Y Lin, S Rickelt, R Zilionis, ... Cell reports 32 (12), 2020 | 102 | 2020 |
Spatial transcriptomics for antigen-receptors C Engblom, K Thrane, J Mold, J Frisen, J Lundeberg, Q Lin US Patent 11,692,218, 2023 | 96 | 2023 |
Mast cell degranulation mediates compound 48/80-induced hyperalgesia in mice D Chatterjea, A Wetzel, M Mack, C Engblom, J Allen, C Mora-Solano, ... Biochemical and biophysical research communications 425 (2), 237-243, 2012 | 87 | 2012 |