| Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing M Yadav, S Jhunjhunwala, QT Phung, P Lupardus, J Tanguay, ... Nature 515 (7528), 572-576, 2014 | 1376 | 2014 |
| Novel antibody–antibiotic conjugate eliminates intracellular S. aureus SM Lehar, T Pillow, M Xu, L Staben, KK Kajihara, R Vandlen, L DePalatis, ... Nature 527 (7578), 323-328, 2015 | 866 | 2015 |
| Structural biology of shared cytokine receptors X Wang, P Lupardus, SL LaPorte, KC Garcia Annual review of immunology 27, 29-60, 2009 | 482 | 2009 |
| An ATR-and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication V Costanzo, D Shechter, PJ Lupardus, KA Cimprich, M Gottesman, ... Molecular cell 11 (1), 203-213, 2003 | 464 | 2003 |
| Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability BEL Lauffer, R Mintzer, R Fong, S Mukund, C Tam, I Zilberleyb, B Flicke, ... Journal of Biological Chemistry 288 (37), 26926-26943, 2013 | 447 | 2013 |
| Kinase inhibition in autoimmunity and inflammation AA Zarrin, K Bao, P Lupardus, D Vucic Nature Reviews Drug Discovery 20 (1), 39-63, 2021 | 360 | 2021 |
| Structure of the pseudokinase–kinase domains from protein kinase TYK2 reveals a mechanism for Janus kinase (JAK) autoinhibition PJ Lupardus, M Ultsch, H Wallweber, P Bir Kohli, AR Johnson, ... Proceedings of the National Academy of Sciences 111 (22), 8025-8030, 2014 | 219 | 2014 |
| A requirement for replication in activation of the ATR-dependent DNA damage checkpoint PJ Lupardus, T Byun, M Yee, M Hekmat-Nejad, KA Cimprich Genes & development 16 (18), 2327-2332, 2002 | 213 | 2002 |
| An in vivo human-plasmablast enrichment technique allows rapid identification of therapeutic influenza A antibodies G Nakamura, N Chai, S Park, N Chiang, Z Lin, H Chiu, R Fong, D Yan, ... Cell host & microbe 14 (1), 93-103, 2013 | 196 | 2013 |
| Positive allosteric modulators of GluN2A-containing NMDARs with distinct modes of action and impacts on circuit function DH Hackos, PJ Lupardus, T Grand, Y Chen, TM Wang, P Reynen, ... Neuron 89 (5), 983-999, 2016 | 175 | 2016 |
| The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12 PJ Lupardus, KC Garcia Journal of molecular biology 382 (4), 931-941, 2008 | 171 | 2008 |
| Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Rα2 PJ Lupardus, ME Birnbaum, KC Garcia Structure 18 (3), 332-342, 2010 | 167 | 2010 |
| Structural basis of recognition of interferon-α receptor by tyrosine kinase 2 HJA Wallweber, C Tam, Y Franke, MA Starovasnik, PJ Lupardus Nature Structural & Molecular Biology 21 (5), 443-448, 2014 | 146 | 2014 |
| Small molecule-induced allosteric activation of the Vibrio cholerae RTX cysteine protease domain PJ Lupardus, A Shen, M Bogyo, KC Garcia Science 322 (5899), 265-268, 2008 | 142 | 2008 |
| Membrane‐delimited coupling between sigma receptors and K+ channels in rat neurohypophysial terminals requires neither G‐protein nor ATP PJ Lupardus, RA Wilke, E Aydar, CP Palmer, Y Chen, AE Ruoho, ... The Journal of Physiology 526 (3), 527-539, 2000 | 135 | 2000 |
| The Janus kinase (JAK) FERM and SH2 domains: bringing specificity to JAK–receptor interactions R Ferrao, PJ Lupardus Frontiers in endocrinology 8, 71, 2017 | 134 | 2017 |
| RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases S Patel, JD Webster, E Varfolomeev, YC Kwon, JH Cheng, J Zhang, ... Cell Death & Differentiation 27 (1), 161-175, 2020 | 127 | 2020 |
| Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires uncoupling of DNA polymerase and mini-chromosome maintenance helicase activities DJ Chang, PJ Lupardus, KA Cimprich Journal of Biological Chemistry 281 (43), 32081-32088, 2006 | 127 | 2006 |
| Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex G Skiniotis, PJ Lupardus, M Martick, T Walz, KC Garcia Molecular cell 31 (5), 737-748, 2008 | 126 | 2008 |
| Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells CR Glassman, YK Mathiharan, KM Jude, L Su, O Panova, PJ Lupardus, ... Cell 184 (4), 983-999. e24, 2021 | 118 | 2021 |