A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum K Brennan, K Martin, SP FitzGerald, J O’sullivan, Y Wu, A Blanco, ... Scientific reports 10 (1), 1039, 2020 | 803 | 2020 |
Heterogeneity of tumor-induced gene expression changes in the human metabolic network J Hu, JW Locasale, JH Bielas, J O'sullivan, K Sheahan, LC Cantley, ... Nature biotechnology 31 (6), 522-529, 2013 | 444 | 2013 |
Chromosomal instability in ulcerative colitis is related to telomere shortening JN O'Sullivan, MP Bronner, TA Brentnall, JC Finley, WT Shen, S Emerson, ... Nature genetics 32 (2), 280-284, 2002 | 401 | 2002 |
Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer LM Wang, D Kevans, H Mulcahy, J O'Sullivan, D Fennelly, J Hyland, ... The American journal of surgical pathology 33 (1), 134-141, 2009 | 354 | 2009 |
Synovial tissue hypoxia and inflammation in vivo CT Ng, M Biniecka, A Kennedy, J McCormick, O Fitzgerald, B Bresnihan, ... Annals of the rheumatic diseases 69 (7), 1389-1395, 2010 | 277 | 2010 |
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue RD Kennedy, M Bylesjo, P Kerr, T Davison, JM Black, EW Kay, RJ Holt, ... Journal of Clinical Oncology 29 (35), 4620-4626, 2011 | 241 | 2011 |
Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers AM Buckley, N Lynam-Lennon, H O’Neill, J O’Sullivan Nature reviews Gastroenterology & hepatology 17 (5), 298-313, 2020 | 218 | 2020 |
Dysregulated bioenergetics: a key regulator of joint inflammation M Biniecka, M Canavan, T McGarry, W Gao, J McCormick, S Cregan, ... Annals of the rheumatic diseases 75 (12), 2192-2200, 2016 | 214 | 2016 |
Overexpression of the microRNA miR‐433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells K Weiner‐Gorzel, E Dempsey, M Milewska, A McGoldrick, V Toh, A Walsh, ... Cancer medicine 4 (5), 745-758, 2015 | 184 | 2015 |
Angiogenesis and blood vessel stability in inflammatory arthritis A Kennedy, CT Ng, M Biniecka, T Saber, C Taylor, J O'Sullivan, DJ Veale, ... Arthritis & Rheumatism 62 (3), 711-721, 2010 | 179 | 2010 |
Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer AJ Michielsen, AE Hogan, J Marry, M Tosetto, F Cox, JM Hyland, ... PloS one 6 (11), e27944, 2011 | 163 | 2011 |
Clusterin biogenesis is altered during apoptosis in the regressing rat ventral prostate J Lakins, SAL Bennett, JH Chen, JM Arnold, C Morrissey, P Wong, ... Journal of Biological Chemistry 273 (43), 27887-27895, 1998 | 155 | 1998 |
Epithelial-mesenchymal transition (EMT) protein expression in a cohort of stage II colorectal cancer patients with characterized tumor budding and mismatch repair protein status D Kevans, LM Wang, K Sheahan, J Hyland, D O’Donoghue, H Mulcahy, ... International journal of surgical pathology 19 (6), 751-760, 2011 | 144 | 2011 |
Emerging concepts linking obesity with the hallmarks of cancer CL Donohoe, J Lysaght, J O'Sullivan, JV Reynolds Trends in endocrinology & metabolism 28 (1), 46-62, 2017 | 135 | 2017 |
Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments J O’Sullivan, J Lysaght, CL Donohoe, JV Reynolds Nature reviews Gastroenterology & hepatology 15 (11), 699-714, 2018 | 134 | 2018 |
Generation of an epigenetic signature by chronic hypoxia in prostate cells JA Watson, CJ Watson, AM McCrohan, K Woodfine, M Tosetto, J McDaid, ... Human molecular genetics 18 (19), 3594-3604, 2009 | 130 | 2009 |
Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis J O'Sullivan, L Whyte, J Drake, M Tenniswood Cell Death & Differentiation 10 (8), 914-927, 2003 | 127 | 2003 |
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett’s esophagus C Palles, L Chegwidden, X Li, JM Findlay, G Farnham, FC Giner, ... Gastroenterology 148 (2), 367-378, 2015 | 123 | 2015 |
Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis M Biniecka, E Fox, W Gao, CT Ng, DJ Veale, U Fearon, J O'Sullivan Arthritis & Rheumatism 63 (8), 2172-2182, 2011 | 121 | 2011 |
Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint M Biniecka, A Kennedy, U Fearon, CT Ng, DJ Veale, JN O'Sullivan Annals of the rheumatic diseases 69 (6), 1172-1178, 2010 | 121 | 2010 |