| Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes SH Shahmoradian, AJ Lewis, C Genoud, J Hench, TE Moors, PP Navarro, ... Nature neuroscience 22 (7), 1099-1109, 2019 | 903 | 2019 |
| Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles S Hennig, G Kong, T Mannen, A Sadowska, S Kobelke, A Blythe, GJ Knott, ... Journal of Cell Biology 210 (4), 529-539, 2015 | 340 | 2015 |
| TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates F Laferrière, Z Maniecka, M Pérez-Berlanga, M Hruska-Plochan, ... Nature neuroscience 22 (1), 65-77, 2019 | 173 | 2019 |
| The ins and outs of lncRNA structure: How, why and what comes next? AJ Blythe, AH Fox, CS Bond Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (1), 46-58, 2016 | 104 | 2016 |
| Determinants of affinity and specificity in RNA-binding proteins S Helder, AJ Blythe, CS Bond, JP Mackay Current opinion in structural biology 38, 83-91, 2016 | 77 | 2016 |
| The design and structural characterization of a synthetic pentatricopeptide repeat protein BS Gully, KR Shah, M Lee, K Shearston, NM Smith, A Sadowska, ... Biological Crystallography 71 (2), 196-208, 2015 | 56 | 2015 |
| Caveolin‐1‐driven membrane remodelling regulates hnRNPK‐mediated exosomal microRNA sorting in cancer H Robinson, JE Ruelcke, A Lewis, CS Bond, AH Fox, V Bharti, S Wani, ... Clinical and translational medicine 11 (4), e381, 2021 | 40 | 2021 |
| Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles PP Navarro, C Genoud, D Castaño-Díez, A Graff-Meyer, AJ Lewis, ... Scientific reports 8 (1), 18046, 2018 | 34 | 2018 |
| Lewy pathology in Parkinson’s disease consists of a crowded organellar, membranous medley SH Shahmoradian, AJ Lewis, C Genoud, J Hench, T Moors, PP Navarro, ... biorxiv, 137976, 2017 | 34 | 2017 |
| Imaging of post-mortem human brain tissue using electron and X-ray microscopy AJ Lewis, C Genoud, M Pont, WDJ Van de Berg, S Frank, H Stahlberg, ... Current opinion in structural biology 58, 138-148, 2019 | 29 | 2019 |
| The yeast transcription elongation factor Spt4/5 is a sequence‐specific RNA binding protein AJ Blythe, B Yazar‐Klosinski, MW Webster, E Chen, M Vandevenne, ... Protein Science 25 (9), 1710-1721, 2016 | 25 | 2016 |
| Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA D Ho, JA Kretzmann, M Norret, P Toshniwal, JP Veder, H Jiang, ... Nature nanotechnology 13 (12), 1148-1153, 2018 | 22 | 2018 |
| FTLD‐TDP assemblies seed neoaggregates with subtype‐specific features via a prion‐like cascade P De Rossi, AJ Lewis, J Furrer, L De Vos, T Demeter, A Zbinden, W Zhong, ... EMBO reports 22 (12), e53877, 2021 | 18 | 2021 |
| The first transcriptomes from field-collected individual whiteflies (Bemisia tabaci, Hemiptera: Aleyrodidae): a case study of the endosymbiont composition P Sseruwagi, J Wainaina, J Ndunguru, R Tumuhimbise, F Tairo, JY Guo, ... Gates Open Research 1, 16, 2018 | 18 | 2018 |
| Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions I Lam, A Ndayisaba, AJ Lewis, YH Fu, GT Sagredo, A Kuzkina, ... Neuron 112 (17), 2886-2909. e16, 2024 | 15 | 2024 |
| Distinct ultrastructural phenotypes of glial and neuronal alpha-synuclein inclusions in multiple system atrophy C Böing, M Di Fabrizio, D Burger, JGJM Bol, E Huisman, AJM Rozemuller, ... Brain 147 (11), 3727-3741, 2024 | 9 | 2024 |
| Alterations in sub-axonal architecture between normal aging and Parkinson’s diseased human brains using label-free cryogenic X-ray nanotomography HT Tran, EHR Tsai, AJ Lewis, T Moors, J Bol, I Rostami, A Diaz, AJ Jonker, ... Frontiers in neuroscience 14, 570019, 2020 | 8 | 2020 |
| Ubiquitin fusion constructs allow the expression and purification of multi-KOW domain complexes of the Saccharomyces cerevisiae transcription elongation factor Spt4/5 A Blythe, S Gunasekara, J Walshe, JP Mackay, GA Hartzog, A Vrielink Protein Expression and Purification 100, 54-60, 2014 | 5 | 2014 |
| Ultrastructural diversity of alpha-Synuclein pathology in the post-mortem brain of Parkinson patients: implications for Lewy Body formation AJ Lewis, L van den Heuvel, M Di Fabrizio, D Burger, E Huisman, ... bioRxiv, 2024.07. 25.605088, 2024 | 1 | 2024 |
| 1.94 Å structure of synthetic α-synuclein fibrils seeding MSA neuropathology D Burger, M Kashyrina, AJ Lewis, F De Nuccio, I Mohammed, ... bioRxiv, 2024.07. 01.601498, 2024 | 1 | 2024 |
