miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA TB Hansen, ED Wiklund, JB Bramsen, SB Villadsen, AL Statham, SJ Clark, ... The EMBO journal 30 (21), 4414-4422, 2011 | 1087 | 2011 |
De novo identification of differentially methylated regions in the human genome TJ Peters, MJ Buckley, AL Statham, R Pidsley, K Samaras, R V Lord, ... Epigenetics & chromatin 8, 1-16, 2015 | 881 | 2015 |
DNA methylation: bisulphite modification and analysis SJ Clark, A Statham, C Stirzaker, PL Molloy, M Frommer Nature protocols 1 (5), 2353-2364, 2006 | 429 | 2006 |
Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements MW Coolen, AL Statham, M Gardiner-Garden, SJ Clark Nucleic acids research 35 (18), e119, 2007 | 269 | 2007 |
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias. SS Nair, MW Coolen, C Stirzaker, JZ Song, AL Statham, D Strbenac, ... Epigenetics: official journal of the DNA Methylation Society 6 (1), 34, 2011 | 253 | 2011 |
Mining cancer methylomes: prospects and challenges C Stirzaker, PC Taberlay, AL Statham, SJ Clark Trends in Genetics 30 (2), 75-84, 2014 | 239 | 2014 |
Regional activation of the cancer genome by long-range epigenetic remodeling SA Bert, MD Robinson, D Strbenac, AL Statham, JZ Song, T Hulf, ... Cancer cell 23 (1), 9-22, 2013 | 238 | 2013 |
CCR6 defines memory B cell precursors in mouse and human germinal centers, revealing light-zone location and predominant low antigen affinity D Suan, NJ Kräutler, JLV Maag, D Butt, K Bourne, JR Hermes, DT Avery, ... Immunity 47 (6), 1142-1153. e4, 2017 | 236 | 2017 |
Acetylation of H2A. Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer F Valdés-Mora, JZ Song, AL Statham, D Strbenac, MD Robinson, SS Nair, ... Genome research 22 (2), 307-321, 2012 | 229 | 2012 |
Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer PC Taberlay, AL Statham, TK Kelly, SJ Clark, PA Jones Genome research 24 (9), 1421-1432, 2014 | 222 | 2014 |
Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA AL Statham, MD Robinson, JZ Song, MW Coolen, C Stirzaker, SJ Clark Genome research 22 (6), 1120-1127, 2012 | 222 | 2012 |
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity MW Coolen, C Stirzaker, JZ Song, AL Statham, Z Kassir, CS Moreno, ... Nature cell biology 12 (3), 235-246, 2010 | 218 | 2010 |
Repitools: an R package for the analysis of enrichment-based epigenomic data AL Statham, D Strbenac, MW Coolen, C Stirzaker, SJ Clark, MD Robinson Bioinformatics 26 (13), 1662-1663, 2010 | 181 | 2010 |
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications C Bock, F Halbritter, FJ Carmona, S Tierling, P Datlinger, Y Assenov, ... Nature biotechnology 34 (7), 726-737, 2016 | 170 | 2016 |
Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation MD Robinson, C Stirzaker, AL Statham, MW Coolen, JZ Song, SS Nair, ... Genome research 20 (12), 1719-1729, 2010 | 150 | 2010 |
Prognostic and diagnostic significance of DNA methylation patterns in high grade serous ovarian cancer C Montavon, BS Gloss, K Warton, CA Barton, AL Statham, JP Scurry, ... Gynecologic oncology 124 (3), 582-588, 2012 | 133 | 2012 |
FAS inactivation releases unconventional germinal center B cells that escape antigen control and drive IgE and autoantibody production D Butt, TD Chan, K Bourne, JR Hermes, A Nguyen, A Statham, ... Immunity 42 (5), 890-902, 2015 | 110 | 2015 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 105 | 2012 |
Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains A Khoury, J Achinger-Kawecka, SA Bert, GC Smith, HJ French, PL Luu, ... Nature communications 11 (1), 54, 2020 | 100 | 2020 |
Enduring epigenetic landmarks define the cancer microenvironment R Pidsley, MG Lawrence, E Zotenko, B Niranjan, A Statham, J Song, ... Genome research 28 (5), 625-638, 2018 | 98 | 2018 |