| DNA damage follows repair factor depletion and portends genome variation in cancer cells after pore migration J Irianto, Y Xia, CR Pfeifer, A Athirasala, J Ji, C Alvey, M Tewari, ... Current Biology 27 (2), 210-223, 2017 | 290 | 2017 |
| Nuclear rupture at sites of high curvature compromises retention of DNA repair factors Y Xia, IL Ivanovska, K Zhu, L Smith, J Irianto, CR Pfeifer, CM Alvey, J Ji, ... Journal of Cell Biology 217 (11), 3796-3808, 2018 | 175 | 2018 |
| Nuclear constriction segregates mobile nuclear proteins away from chromatin J Irianto, CR Pfeifer, RR Bennett, Y Xia, IL Ivanovska, AJ Liu, ... Molecular biology of the cell 27 (25), 4011-4020, 2016 | 132 | 2016 |
| SIRPA-inhibited, marrow-derived macrophages engorge, accumulate, and differentiate in antibody-targeted regression of solid tumors CM Alvey, KR Spinler, J Irianto, CR Pfeifer, B Hayes, Y Xia, S Cho, ... Current Biology 27 (14), 2065-2077. e6, 2017 | 130 | 2017 |
| Nuclear lamins in cancer J Irianto, CR Pfeifer, IL Ivanovska, J Swift, DE Discher Cellular and molecular bioengineering 9, 258-267, 2016 | 130 | 2016 |
| Constricted migration increases DNA damage and independently represses cell cycle CR Pfeifer, Y Xia, K Zhu, D Liu, J Irianto, VMM García, LMS Millán, ... Molecular biology of the cell 29 (16), 1948-1962, 2018 | 124 | 2018 |
| Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle Y Xia, CR Pfeifer, K Zhu, J Irianto, D Liu, K Pannell, EJ Chen, LJ Dooling, ... Journal of Cell Biology 218 (8), 2545-2563, 2019 | 95 | 2019 |
| Reciprocal cell-ECM dynamics generate supracellular fluidity underlying spontaneous follicle patterning KH Palmquist, SF Tiemann, FL Ezzeddine, S Yang, CR Pfeifer, ... Cell 185 (11), 1960-1973. e11, 2022 | 73 | 2022 |
| Genome variation across cancers scales with tissue stiffness–an invasion-mutation mechanism and implications for immune cell infiltration CR Pfeifer, CM Alvey, J Irianto, DE Discher Current opinion in systems biology 2, 103-114, 2017 | 73 | 2017 |
| Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM CR Pfeifer, A Shomorony, MA Aronova, G Zhang, T Cai, H Xu, AL Notkins, ... Journal of structural biology 189 (1), 44-52, 2015 | 72 | 2015 |
| SnapShot: mechanosensing matrix J Irianto, CR Pfeifer, Y Xia, DE Discher Cell 165 (7), 1820-1820. e1, 2016 | 68 | 2016 |
| Granular discharge rate for submerged hoppers TJ Wilson, CR Pfeifer, N Meysingier, DJ Durian Papers in physics 6 (2), 0-0, 2014 | 61 | 2014 |
| As a nucleus enters a small pore, chromatin stretches and maintains integrity, even with DNA breaks J Irianto, Y Xia, CR Pfeifer, RA Greenberg, DE Discher Biophysical journal 112 (3), 446-449, 2017 | 57 | 2017 |
| Constricted migration modulates stem cell differentiation LR Smith, J Irianto, Y Xia, CR Pfeifer, DE Discher Molecular biology of the cell 30 (16), 1985-1999, 2019 | 38 | 2019 |
| Nuclear mechanics during and after constricted migration Y Xia, CR Pfeifer, DE Discher Acta Mechanica Sinica 35, 299-308, 2019 | 36 | 2019 |
| Nuclear failure, DNA damage, and cell cycle disruption after migration through small pores: a brief review CR Pfeifer, M Vashisth, Y Xia, DE Discher Essays in Biochemistry 63 (5), 569-577, 2019 | 35 | 2019 |
| Scaling laws indicate distinct nucleation mechanisms of holes in the nuclear lamina D Deviri, CR Pfeifer, LJ Dooling, IL Ivanovska, DE Discher, SA Safran Nature Physics 15 (8), 823-829, 2019 | 34 | 2019 |
| Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate CR Pfeifer, MP Tobin, S Cho, M Vashisth, LJ Dooling, LL Vazquez, ... Nucleus 13 (1), 130-144, 2022 | 30 | 2022 |
| Nuclear mechanosensing Y Xia, CR Pfeifer, S Cho, DE Discher, J Irianto Emerging Topics in Life Sciences 2 (5), 713-725, 2018 | 26 | 2018 |
| Elastic-fluid model for DNA damage and mutation from nuclear fluid segregation due to cell migration RR Bennett, CR Pfeifer, J Irianto, Y Xia, DE Discher, AJ Liu Biophysical journal 112 (11), 2271-2279, 2017 | 26 | 2017 |
Dennis DischerUniversity of PennsylvaniaEmail được xác minh tại seas.upenn.edu