The Tohoku medical megabank project: design and mission S Kuriyama, N Yaegashi, F Nagami, T Arai, Y Kawaguchi, N Osumi, ... Journal of epidemiology 26 (9), 493-511, 2016 | 326 | 2016 |
A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv (3)(q21; q26) by activating EVI1 expression H Yamazaki, M Suzuki, A Otsuki, R Shimizu, EH Bresnick, JD Engel, ... Cancer cell 25 (4), 415-427, 2014 | 282 | 2014 |
Essential and instructive roles of GATA factors in eosinophil development R Hirasawa, R Shimizu, S Takahashi, M Osawa, S Takayanagi, Y Kato, ... The Journal of experimental medicine 195 (11), 1379-1386, 2002 | 278 | 2002 |
In vivo requirements for GATA‐1 functional domains during primitive and definitive erythropoiesis R Shimizu, S Takahashi, K Ohneda, JD Engel, M Yamamoto The EMBO journal, 2001 | 181 | 2001 |
Cohort profile: Tohoku medical megabank project birth and three-generation cohort study (TMM BirThree cohort study): rationale, progress and perspective S Kuriyama, H Metoki, M Kikuya, T Obara, M Ishikuro, C Yamanaka, ... International journal of epidemiology 49 (1), 18-19m, 2020 | 156 | 2020 |
The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice K Tatsumi, H Yamamoto-Mukai, R Shimizu, S Waguri, YS Sou, ... Nature communications 2 (1), 181, 2011 | 155 | 2011 |
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling J Guiu, R Shimizu, T D’Altri, ST Fraser, J Hatakeyama, EH Bresnick, ... Journal of Experimental Medicine 210 (1), 71-84, 2013 | 149 | 2013 |
GATA1-related leukaemias R Shimizu, JD Engel, M Yamamoto Nature Reviews Cancer 8 (4), 279-287, 2008 | 144 | 2008 |
GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies S Takahashi, R Shimizu, N Suwabe, T Kuroha, K Yoh, J Ohta, ... Blood, The Journal of the American Society of Hematology 96 (3), 910-916, 2000 | 139 | 2000 |
Study profile of the Tohoku medical megabank community-based cohort study A Hozawa, K Tanno, N Nakaya, T Nakamura, N Tsuchiya, T Hirata, ... Journal of epidemiology 31 (1), 65-76, 2021 | 129 | 2021 |
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation M Khandekar, W Brandt, Y Zhou, S Dagenais, TW Glover, N Suzuki, ... Oxford University Press for The Company of Biologists Limited 134 (9), 1703-1712, 2007 | 121 | 2007 |
Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line. HY Ren, N Komatsu, R Shimizu, K Okada, Y Miura Journal of Biological Chemistry 269 (30), 19633-19638, 1994 | 114 | 1994 |
Conformational change in transfer RNA is an early indicator of acute cellular damage E Mishima, C Inoue, D Saigusa, R Inoue, K Ito, Y Suzuki, D Jinno, ... Journal of the American Society of Nephrology 25 (10), 2316-2326, 2014 | 113 | 2014 |
GATA factor switching during erythroid differentiation H Kaneko, R Shimizu, M Yamamoto Current opinion in hematology 17 (3), 163-168, 2010 | 111 | 2010 |
Leukemogenesis caused by incapacitated GATA-1 function R Shimizu, T Kuroha, O Ohneda, X Pan, K Ohneda, S Takahashi, ... Molecular and Cellular Biology 24 (24), 10814-10825, 2004 | 103 | 2004 |
GATA factor switching from GATA 2 to GATA 1 contributes to erythroid differentiation M Suzuki, M Kobayashi‐Osaki, S Tsutsumi, X Pan, S Ohmori, J Takai, ... Genes to Cells 18 (11), 921-933, 2013 | 102 | 2013 |
Gene expression regulation and domain function of hematopoietic GATA factors R Shimizu, M Yamamoto Seminars in cell & developmental biology 16 (1), 129-136, 2005 | 92 | 2005 |
A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21 Y Kazuki, FJ Gao, Y Li, AJ Moyer, B Devenney, K Hiramatsu, ... Elife 9, e56223, 2020 | 89 | 2020 |
Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis Z Kadri, R Shimizu, O Ohneda, L Maouche-Chretien, S Gisselbrecht, ... PLoS biology 7 (6), e1000123, 2009 | 87 | 2009 |
Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia Y Kawatani, T Suzuki, R Shimizu, VP Kelly, M Yamamoto Blood, The Journal of the American Society of Hematology 117 (3), 986-996, 2011 | 81 | 2011 |