Transposable elements drive widespread expression of oncogenes in human cancers HS Jang, NM Shah, AY Du, ZZ Dailey, EC Pehrsson, PM Godoy, D Zhang, ... Nature genetics 51 (4), 611-617, 2019 | 331 | 2019 |
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 302 | 2017 |
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation J Zhou, RL Sears, X Xing, B Zhang, D Li, NB Rockweiler, HS Jang, ... BMC genomics 18, 1-17, 2017 | 114 | 2017 |
Co-opted transposons help perpetuate conserved higher-order chromosomal structures MNK Choudhary, RZ Friedman, JT Wang, HS Jang, X Zhuo, T Wang Genome biology 21, 1-14, 2020 | 107 | 2020 |
Evolution of epigenetic regulation in vertebrate genomes RF Lowdon, HS Jang, T Wang Trends in Genetics 32 (5), 269-283, 2016 | 93 | 2016 |
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements NM Shah, HJ Jang, Y Liang, JH Maeng, SC Tzeng, A Wu, NL Basri, X Qu, ... Nature genetics 55 (4), 631-639, 2023 | 80 | 2023 |
Regenerating zebrafish fin epigenome is characterized by stable lineage-specific DNA methylation and dynamic chromatin accessibility HJ Lee, Y Hou, Y Chen, ZZ Dailey, A Riddihough, HS Jang, T Wang, ... Genome biology 21, 1-17, 2020 | 58 | 2020 |
Transcription Start Site Evolution in Drosophila BJ Main, AD Smith, H Jang, SV Nuzhdin Molecular biology and evolution 30 (8), 1966-1974, 2013 | 35 | 2013 |
Genome-wide characterization of genetic variation in the unicellular, green alga Chlamydomonas reinhardtii H Jang, IM Ehrenreich PLoS One 7 (7), e41307, 2012 | 26 | 2012 |
A phase II trial of guadecitabine plus atezolizumab in metastatic urothelial carcinoma progressing after initial immune checkpoint inhibitor therapy HJ Jang, G Hostetter, AW Macfarlane, Z Madaj, EA Ross, T Hinoue, ... Clinical Cancer Research 29 (11), 2052-2065, 2023 | 22 | 2023 |
Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish HS Jang, Y Chen, J Ge, AN Wilkening, Y Hou, HJ Lee, YR Choi, ... Genome biology 22, 1-18, 2021 | 18 | 2021 |
RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer HT Li, HJ Jang, K Rohena-Rivera, M Liu, H Gujar, J Kulchycki, S Zhao, ... Cell reports 42 (1), 2023 | 16 | 2023 |
Safety, outcomes, and T-cell characteristics in patients with relapsed or refractory MDS or CMML treated with atezolizumab in combination with guadecitabine CL O'Connell, MR Baer, AD Ørskov, SK Saini, VH Duong, P Kropf, ... Clinical Cancer Research 28 (24), 5306-5316, 2022 | 16 | 2022 |
Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis JA Karlow, S Devarakonda, X Xing, HS Jang, R Govindan, M Watson, ... Cancer research 82 (15), 2692-2703, 2022 | 14 | 2022 |
DeepH&M: Estimating single-CpG hydroxymethylation and methylation levels from enrichment and restriction enzyme sequencing methods Y He, HS Jang, X Xing, D Li, MJ Vasek, JD Dougherty, T Wang Science Advances 6 (27), eaba0521, 2020 | 13 | 2020 |
Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy TG Kang, X Lan, T Mi, H Chen, S Alli, SE Lim, S Bhatara, AB Vasandan, ... Science 386 (6718), eadl4492, 2024 | 10 | 2024 |
Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome JH Maeng, HJ Jang, AY Du, SC Tzeng, T Wang Genome research 33 (12), 2143-2155, 2023 | 7 | 2023 |
Efficient activation of hundreds of LTR12C elements reveals cis-regulatory function determined by distinct epigenetic mechanisms H Ohtani, M Liu, G Liang, HJ Jang, PA Jones Nucleic Acids Research 52 (14), 8205-8217, 2024 | 4 | 2024 |
Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells HJ Jang, NM Shah, JH Maeng, Y Liang, NL Basri, J Ge, X Qu, ... Nature Genetics 56 (9), 1903-1913, 2024 | 2 | 2024 |
H3K9me3 loss and ERVs activation as hallmarks for osteoarthritis progression and knee joint aging Y Liu, V Molchanov, Y Zhao, D Lu, H Liu, HJ Jang, T Yang Osteoarthritis and Cartilage 33 (1), 128-133, 2025 | | 2025 |