Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair K Lee, M Conboy, HM Park, F Jiang, HJ Kim, MA Dewitt, VA Mackley, ... Nature biomedical engineering 1 (11), 889-901, 2017 | 776 | 2017 |
Recent progress in development of siRNA delivery vehicles for cancer therapy HJ Kim, A Kim, K Miyata, K Kataoka Advanced drug delivery reviews 104, 61-77, 2016 | 441 | 2016 |
Charge‐Conversional Polyionic Complex Micelles—Efficient Nanocarriers for Protein Delivery into Cytoplasm Y Lee, T Ishii, H Cabral, HJ Kim, JH Seo, N Nishiyama, H Oshima, ... Angewandte Chemie International Edition 48 (29), 5309-5312, 2009 | 375 | 2009 |
Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment K Katsushima, A Natsume, F Ohka, K Shinjo, A Hatanaka, N Ichimura, ... Nature communications 7 (1), 13616, 2016 | 320 | 2016 |
Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection RJ Christie, Y Matsumoto, K Miyata, T Nomoto, S Fukushima, K Osada, ... Acs Nano 6 (6), 5174-5189, 2012 | 226 | 2012 |
Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles Y Lee, T Ishii, HJ Kim, N Nishiyama, Y Hayakawa, K Itaka, K Kataoka Angewandte Chemie-International Edition 49 (14), 2552-2555, 2010 | 223 | 2010 |
Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with … F Pittella, M Zhang, Y Lee, HJ Kim, T Tockary, K Osada, T Ishii, K Miyata, ... Biomaterials 32 (11), 3106-3114, 2011 | 206 | 2011 |
Systemic brain delivery of antisense oligonucleotides across the blood–brain barrier with a glucose‐coated polymeric nanocarrier HS Min, HJ Kim, M Naito, S Ogura, K Toh, K Hayashi, BS Kim, ... Angewandte Chemie International Edition 59 (21), 8173-8180, 2020 | 185 | 2020 |
Virus‐mimicking chimaeric polymersomes boost targeted cancer siRNA therapy in vivo Y Zou, M Zheng, W Yang, F Meng, K Miyata, HJ Kim, K Kataoka, Z Zhong Advanced Materials 29 (42), 1703285, 2017 | 147 | 2017 |
Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles HJ Kim, H Takemoto, Y Yi, M Zheng, Y Maeda, H Chaya, K Hayashi, P Mi, ... ACS nano 8 (9), 8979-8991, 2014 | 145 | 2014 |
Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles F Pittella, H Cabral, Y Maeda, P Mi, S Watanabe, H Takemoto, HJ Kim, ... Journal of controlled release 178, 18-24, 2014 | 137 | 2014 |
Introduction of stearoyl moieties into a biocompatible cationic polyaspartamide derivative, PAsp (DET), with endosomal escaping function for enhanced siRNA-mediated gene knockdown HJ Kim, A Ishii, K Miyata, Y Lee, S Wu, M Oba, N Nishiyama, K Kataoka Journal of controlled release 145 (2), 141-148, 2010 | 132 | 2010 |
Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells Y Yi, HJ Kim, M Zheng, P Mi, M Naito, BS Kim, HS Min, K Hayashi, ... Journal of Controlled Release 295, 268-277, 2019 | 114 | 2019 |
Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles Y Yi, HJ Kim, P Mi, M Zheng, H Takemoto, K Toh, BS Kim, K Hayashi, ... Journal of Controlled Release 244, 247-256, 2016 | 107 | 2016 |
siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core HJ Kim, K Miyata, T Nomoto, M Zheng, A Kim, X Liu, H Cabral, RJ Christie, ... Biomaterials 35 (15), 4548-4556, 2014 | 95 | 2014 |
Fine-Tuning of Hydrophobicity in Amphiphilic Polyaspartamide Derivatives for Rapid and Transient Expression of Messenger RNA Directed Toward Genome Engineering in Brain HJ Kim, S Ogura, T Otabe, R Kamegawa, M Sato, K Kataoka, K Miyata ACS central science 5 (11), 1866-1875, 2019 | 75 | 2019 |
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers S Watanabe, K Hayashi, K Toh, HJ Kim, X Liu, H Chaya, S Fukushima, ... Nature communications 10 (1), 1894, 2019 | 74 | 2019 |
In vivo delivery of transcription factors with multifunctional oligonucleotides K Lee, M Rafi, X Wang, K Aran, X Feng, C Lo Sterzo, R Tang, ... Nature materials 14 (7), 701-706, 2015 | 73 | 2015 |
Self-Assembly of siRNA/PEG-b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo … BS Kim, S Chuanoi, T Suma, Y Anraku, K Hayashi, M Naito, HJ Kim, ... Journal of the American Chemical Society 141 (8), 3699-3709, 2019 | 65 | 2019 |
Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells K Lee, P Yu, N Lingampalli, HJ Kim, R Tang, N Murthy International journal of nanomedicine, 1841-1854, 2015 | 62 | 2015 |