| Investigation of matrix effects in bioanalytical high‐performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery H Mei, Y Hsieh, C Nardo, X Xu, S Wang, K Ng, WA Korfmacher Rapid Communications in Mass Spectrometry 17 (1), 97-103, 2003 | 485 | 2003 |
| Direct analysis of drug candidates in tissue by matrix‐assisted laser desorption/ionization mass spectrometry ML Reyzer, Y Hsieh, K Ng, WA Korfmacher, RM Caprioli Journal of Mass Spectrometry 38 (10), 1081-1092, 2003 | 448 | 2003 |
| Foundation review: Principles and applications of LC-MS in new drug discovery WA Korfmacher Drug discovery today 10 (20), 1357-1367, 2005 | 426 | 2005 |
| Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice M Liu, MS Bryant, J Chen, S Lee, B Yaremko, P Lipari, M Malkowski, ... Cancer research 58 (21), 4947-4956, 1998 | 389 | 1998 |
| Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3 … S Venkatraman, SL Bogen, A Arasappan, F Bennett, K Chen, E Jao, ... Journal of medicinal chemistry 49 (20), 6074-6086, 2006 | 325 | 2006 |
| Peer reviewed: systematic LC/MS metabolite identification in drug discovery NJ Clarke, D Rindgen, WA Korfmacher, KA Cox Analytical chemistry 73 (15), 430 A-439 A, 2001 | 249 | 2001 |
| Matrix‐assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue Y Hsieh, R Casale, E Fukuda, J Chen, I Knemeyer, J Wingate, R Morrison, ... Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2006 | 218 | 2006 |
| Liquid extraction surface analysis mass spectrometry (LESA‐MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example D Eikel, M Vavrek, S Smith, C Bason, S Yeh, WA Korfmacher, JD Henion Rapid communications in mass spectrometry 25 (23), 3587-3596, 2011 | 206 | 2011 |
| It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS R Ramanathan, M Jemal, S Ramagiri, YQ Xia, WG Humpreys, T Olah, ... Journal of mass spectrometry 46 (6), 595-601, 2011 | 200 | 2011 |
| Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry Y Hsieh, J Chen, WA Korfmacher Journal of pharmacological and toxicological methods 55 (2), 193-200, 2007 | 175 | 2007 |
| Cassette‐accelerated rapid rat screen: a systematic procedure for the dosing and liquid chromatography/atmospheric pressure ionization tandem mass spectrometric analysis of new … WA Korfmacher, KA Cox, KJ Ng, J Veals, Y Hsieh, S Wainhaus, L Broske, ... Rapid Communications in Mass Spectrometry 15 (5), 335-340, 2001 | 173 | 2001 |
| Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast‐gradient liquid chromatography/tandem mass spectrometry Y Hsieh, M Chintala, H Mei, J Agans, JM Brisson, K Ng, WA Korfmacher Rapid communications in mass spectrometry 15 (24), 2481-2487, 2001 | 165 | 2001 |
| Using mass spectrometry for drug metabolism studies WA Korfmacher CRC Press, 2009 | 122 | 2009 |
| HPLC-API/MS/MS: a powerful tool for integrating drug metabolism into the drug discovery process WA Korfmacher, KA Cox, MS Bryant, J Veals, K Ng, C Lin, R Watkins Drug Discovery Today 2 (12), 532-537, 1997 | 119 | 1997 |
| Combined capillary gas chromatography/atmospheric pressure negative chemical ionization/mass spectrometry for the determination of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in tissue RK Mitchum, GF Moler, WA Korfmacher Analytical Chemistry 52 (14), 2278-2282, 1980 | 116 | 1980 |
| High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma Y Hsieh, K Merkle, G Wang, JM Brisson, WA Korfmacher Analytical chemistry 75 (13), 3122-3127, 2003 | 113 | 2003 |
| Development of an automated mass spectrometry system for the quantitative analysis of liver microsomal incubation samples: a tool for rapid screening of new compounds for … WA Korfmacher, CA Palmer, C Nardo, K Dunn‐Meynell, D Grotz, K Cox, ... Rapid communications in mass spectrometry 13 (10), 901-907, 1999 | 111 | 1999 |
| Chiral liquid chromatography-tandem mass spectrometric methods for stereoisomeric pharmaceutical determinations J Chen, WA Korfmacher, Y Hsieh Journal of Chromatography B 820 (1), 1-8, 2005 | 104 | 2005 |
| Novel in vivo procedure for rapid pharmacokinetic screening of discovery compounds in rats KA Cox, K Dunn-Meynell, WA Korfmacher, L Broske, AA Nomeir, CC Lin, ... Drug discovery today 4 (5), 232-237, 1999 | 103 | 1999 |
| Simultaneous determination of a drug candidate and its metabolite in rat plasma samples using ultrafast monolithic column high‐performance liquid chromatography/tandem mass … Y Hsieh, G Wang, Y Wang, S Chackalamannil, JM Brisson, K Ng, ... Rapid communications in mass spectrometry 16 (10), 944-950, 2002 | 100 | 2002 |