| Assembly of purified GDP-tubulin into microtubules induced by taxol and taxotere: reversibility, ligand stoichiometry, and competition JF Diaz, JM Andreu Biochemistry 32 (11), 2747-2755, 1993 | 559 | 1993 |
| Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action M Abal, JM Andreu, I Barasoain Current cancer drug targets 3 (3), 193-203, 2003 | 527 | 2003 |
| Low-resolution structures of proteins in solution retrieved from X-ray scattering with a genetic algorithm P Chacon, F Moran, JF Diaz, E Pantos, JM Andreu Biophysical Journal 74 (6), 2760-2775, 1998 | 370 | 1998 |
| The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for … DE Pryor, A O'Brate, G Bilcer, JF Díaz, Y Wang, Y Wang, M Kabaki, ... Biochemistry 41 (29), 9109-9115, 2002 | 311 | 2002 |
| A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs AE Prota, K Bargsten, JF Diaz, M Marsh, C Cuevas, M Liniger, C Neuhaus, ... Proceedings of the National Academy of Sciences 111 (38), 13817-13821, 2014 | 289 | 2014 |
| Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships A Beloqui, M Pita, J Polaina, A Martínez-Arias, OV Golyshina, ... Journal of Biological Chemistry 281 (32), 22933-22942, 2006 | 260 | 2006 |
| Peloruside A does not bind to the taxoid site on β-tubulin and retains its activity in multidrug-resistant cell lines TN Gaitanos, RM Buey, JF Díaz, PT Northcote, P Teesdale-Spittle, ... Cancer research 64 (15), 5063-5067, 2004 | 260 | 2004 |
| Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity RM Buey, I Barasoain, E Jackson, A Meyer, P Giannakakou, I Paterson, ... Chemistry & biology 12 (12), 1269-1279, 2005 | 258 | 2005 |
| Magnesium-induced linear self-association of the FtsZ bacterial cell division protein monomer: the primary steps for FtsZ assembly G Rivas, A López, J Mingorance, MJ Ferrándiz, S Zorrilla, AP Minton, ... Journal of Biological Chemistry 275 (16), 11740-11749, 2000 | 233 | 2000 |
| Essential cell division protein FtsZ assembles into one monomer-thick ribbons under conditions resembling the crowded intracellular environment JM González, M Jiménez, M Vélez, J Mingorance, JM Andreu, M Vicente, ... Journal of Biological Chemistry 278 (39), 37664-37671, 2003 | 219 | 2003 |
| The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation JM Andreu, C Schaffner-Barbero, S Huecas, D Alonso, ... Journal of Biological Chemistry 285 (19), 14239-14246, 2010 | 208 | 2010 |
| Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin JM Andreu, SN Timasheff Biochemistry 21 (25), 6465-6476, 1982 | 197 | 1982 |
| Interaction of tubulin with single ring analogs of colchicine JM Andreu, SN Timasheff Biochemistry 21 (3), 534-543, 1982 | 189 | 1982 |
| Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites RM Buey, E Calvo, I Barasoain, O Pineda, MC Edler, R Matesanz, ... Nature Chemical Biology 3 (2), 117-125, 2007 | 179 | 2007 |
| Molecular recognition of taxol by microtubules: Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed site JF Dıaz, R Strobe, Y Engelborghs, AA Souto, JM Andreu Journal of Biological Chemistry 275 (34), 26265-26276, 2000 | 178 | 2000 |
| Changes in microtubule protofilament number induced by taxol binding to an easily accessible site: internal microtubule dynamics JF Dıaz, JM Valpuesta, P Chacón, G Diakun, JM Andreu Journal of Biological Chemistry 273 (50), 33803-33810, 1998 | 178 | 1998 |
| Low resolution structure of microtubules in solution: Synchrotron X-ray scattering and electron microscopy of taxol-induced microtubules assembled from purified tubulin in … JM Andreu, J Bordas, JF Diaz, JG de Ancos, R Gil, FJ Medrano, ... Journal of molecular biology 226 (1), 169-184, 1992 | 177 | 1992 |
| Structure of bacterial tubulin BtubA/B: evidence for horizontal gene transfer D Schlieper, MA Oliva, JM Andreu, J Löwe Proceedings of the National Academy of Sciences 102 (26), 9170-9175, 2005 | 175 | 2005 |
| Reconstruction of protein form with X-ray solution scattering and a genetic algorithm P Chacón, JF Dıaz, F Morán, JM Andreu Journal of Molecular Biology 299 (5), 1289-1302, 2000 | 162 | 2000 |
| Interaction of epothilone analogs with the paclitaxel binding site: relationship between binding affinity, microtubule stabilization, and cytotoxicity RM Buey, JF Dı́az, JM Andreu, A O'Brate, P Giannakakou, KC Nicolaou, ... Cell Chemical Biology 11 (2), 225-236, 2004 | 161 | 2004 |