PTEN function: the long and the short of it BD Hopkins, C Hodakoski, D Barrows, SM Mense, RE Parsons Trends in biochemical sciences 39 (4), 183-190, 2014 | 371 | 2014 |
Establishment, maintenance, and recall of inflammatory memory SB Larsen, CJ Cowley, SM Sajjath, D Barrows, Y Yang, TS Carroll, ... Cell stem cell 28 (10), 1758-1774. e8, 2021 | 181 | 2021 |
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands DN Weinberg, P Rosenbaum, X Chen, D Barrows, C Horth, MR Marunde, ... Nature genetics 53 (6), 794-800, 2021 | 89 | 2021 |
Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis CR McNamara, R Ahuja, AD Osafo-Addo, D Barrows, A Kettenbach, ... PLoS One 8 (3), e56576, 2013 | 83 | 2013 |
PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion SM Mense, D Barrows, C Hodakoski, N Steinbach, D Schoenfeld, W Su, ... Science signaling 8 (370), ra32-ra32, 2015 | 80 | 2015 |
Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis C Hodakoski, BD Hopkins, D Barrows, SM Mense, M Keniry, KE Anderson, ... Proceedings of the National Academy of Sciences 111 (1), 155-160, 2014 | 76 | 2014 |
ZBTB1 regulates asparagine synthesis and leukemia cell response to L-asparaginase RT Williams, R Guarecuco, LA Gates, D Barrows, MC Passarelli, B Carey, ... Cell metabolism 31 (4), 852-861. e6, 2020 | 61 | 2020 |
Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer D Barrows, L Feng, TS Carroll, CD Allis Proceedings of the National Academy of Sciences 117 (41), 25732-25741, 2020 | 37 | 2020 |
A molecular switch between mammalian MLL complexes dictates response to Menin–MLL inhibition YM Soto-Feliciano, FJ Sánchez-Rivera, F Perner, DW Barrows, ... Cancer discovery 13 (1), 146-169, 2023 | 36 | 2023 |
PREX1 protein function is negatively regulated downstream of receptor tyrosine kinase activation by p21-activated kinases (PAKs) D Barrows, JZ He, R Parsons Journal of Biological Chemistry 291 (38), 20042-20054, 2016 | 26 | 2016 |
p21-activated kinases (PAKs) mediate the phosphorylation of PREX2 protein to initiate feedback inhibition of Rac1 GTPase D Barrows, SM Schoenfeld, C Hodakoski, A Silkov, B Honig, A Couvillon, ... Journal of Biological Chemistry 290 (48), 28915-28931, 2015 | 25 | 2015 |
Pharmacological targeting of glutamatergic neurons within the brainstem for weight reduction M Schneeberger, NL Brice, K Pellegrino, L Parolari, JT Shaked, KJ Page, ... Nature Metabolism 4 (11), 1495-1513, 2022 | 20 | 2022 |
profileplyr: Visualization and annotation of read signal over genomic ranges with profileplyr T Carroll, D Barrows R package version 1 (1), 2021 | 20 | 2021 |
The integrated stress response remodels the microtubule-organizing center to clear unfolded proteins following proteotoxic stress B Hurwitz, N Guzzi, A Gola, VF Fiore, A Sendoel, M Nikolova, D Barrows, ... Elife 11, e77780, 2022 | 9 | 2022 |
Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation BA Nacev, Y Dabas, MR Paul, C Pacheco, M Mitchener, Y Perez, Y Fang, ... Nature communications 15 (1), 5155, 2024 | 5 | 2024 |
Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells EA Rosado-Olivieri, B Razooky, J Le Pen, R De Santis, D Barrows, ... Stem Cell Reports 18 (5), 1107-1122, 2023 | 4 | 2023 |
Effect of the DASH diet on the sodium-chloride cotransporter and aquaporin-2 in urinary extracellular vesicles D Bielopolski, L Musante, EJ Hoorn, H Molina, D Barrows, TS Carrol, ... American Journal of Physiology-Renal Physiology 326 (6), F971-F980, 2024 | 2 | 2024 |
ATRX guards against aberrant differentiation in mesenchymal progenitor cells Y Fang, D Barrows, Y Dabas, TS Carroll, S Singer, WD Tap, BA Nacev Nucleic Acids Research 52 (9), 4950-4968, 2024 | 1 | 2024 |
MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression R Lin, D Barrows, Y Mo, T Onikubo, Z Zhang, RG Roeder bioRxiv, 2024.03. 18.585606, 2024 | 1 | 2024 |
Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation L Feng, D Barrows, L Zhong, K Mätlik, EG Porter, AM Djomo, I Yau, ... bioRxiv, 2023 | 1 | 2023 |