Model-Based Analysis of Biopharmaceutic Experiments To Improve Mechanistic Oral Absorption Modeling: An Integrated in Vitro in Vivo Extrapolation Perspective … SM Pathak, A Ruff, ES Kostewicz, N Patel, DB Turner, M Jamei Molecular pharmaceutics 14 (12), 4305-4320, 2017 | 87 | 2017 |
In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole B Hens, SM Pathak, A Mitra, N Patel, B Liu, S Patel, M Jamei, J Brouwers, ... Molecular pharmaceutics 14 (12), 4321-4333, 2017 | 75 | 2017 |
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results A Margolskee, AS Darwich, X Pepin, L Aarons, A Galetin, ... European Journal of Pharmaceutical Sciences 96, 610-625, 2017 | 70 | 2017 |
Enhanced oral absorption of saquinavir with methyl-beta-cyclodextrin—preparation and in vitro and in vivo evaluation SM Pathak, P Musmade, S Dengle, A Karthik, K Bhat, N Udupa European journal of pharmaceutical sciences 41 (3-4), 440-451, 2010 | 58 | 2010 |
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across … AS Darwich, A Margolskee, X Pepin, L Aarons, A Galetin, ... European Journal of Pharmaceutical Sciences 96, 626-642, 2017 | 50 | 2017 |
Biopharmaceutic IVIVE—mechanistic modeling of single-and two-phase in vitro experiments to obtain drug-specific parameters for incorporation into PBPK models SM Pathak, KJ Schaefer, M Jamei, DB Turner Journal of pharmaceutical sciences 108 (4), 1604-1618, 2019 | 45 | 2019 |
The regional-specific relative and absolute expression of gut transporters in adult caucasians: a meta-analysis MD Harwood, M Zhang, SM Pathak, S Neuhoff Drug Metabolism and Disposition 47 (8), 854-864, 2019 | 44 | 2019 |
IMI–oral biopharmaceutics tools project–evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds A Margolskee, AS Darwich, X Pepin, SM Pathak, MB Bolger, L Aarons, ... European Journal of Pharmaceutical Sciences 96, 598-609, 2017 | 44 | 2017 |
Evaluation of chemical interactions of maleic acid with sodium hypochlorite and chlorhexidine gluconate NV Ballal, S Moorkoth, K Mala, KS Bhat, SS Hussen, S Pathak Journal of endodontics 37 (10), 1402-1405, 2011 | 41 | 2011 |
A simple and rapid high performance liquid chromatographic method with fluorescence detection for the estimation of fexofenadine in rat plasma—application to preclinical … SM Pathak, AR Kumar, P Musmade, N Udupa Talanta 76 (2), 338-346, 2008 | 39 | 2008 |
Best practices in the development and validation of physiologically based biopharmaceutics modeling. A workshop summary report N Parrott, S Suarez-Sharp, F Kesisoglou, SM Pathak, D Good, C Wagner, ... Journal of pharmaceutical sciences 110 (2), 584-593, 2021 | 31 | 2021 |
Critical attributes of transdermal drug delivery system (TDDS)–a generic product development review PK Ruby, SM Pathak, D Aggarwal Drug development and industrial pharmacy 40 (11), 1421-1428, 2014 | 31 | 2014 |
IMI–Oral biopharmaceutics tools project–Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling … A Ahmad, X Pepin, L Aarons, Y Wang, AS Darwich, JM Wood, ... European Journal of Pharmaceutics and Biopharmaceutics 156, 50-63, 2020 | 28 | 2020 |
Pre‐clinical evidence of enhanced oral bioavailability of the P‐glycoprotein substrate talinolol in combination with morin SM Pathak, N Udupa Biopharmaceutics & Drug Disposition 31 (2‐3), 202-214, 2010 | 24 | 2010 |
Practical and operational considerations related to paediatric oral drug formulation: An industry survey M Van der Veken, J Brouwers, V Budts, L Lauwerys, SM Pathak, ... International journal of pharmaceutics 618, 121670, 2022 | 18 | 2022 |
Development and validation of a reversed-phase liquid chromatographic method with fluorescence detection for the study of Saquinavir pharmacokinetics in rat plasma SM Pathak, AR Kumar, G Subramanian, N Udupa Analytica chimica acta 594 (2), 248-256, 2007 | 18 | 2007 |
High Performance Liquid Chromatographic Method for the Determination of Clobetasol in Rat Plasma and its Application to Skin Penetration PB Musmade, PB Deshpande, SJ Dengle, KB Talole, SM Pathak, ... Journal of Bioanalysis & Biomedicine 2, 2010 | 13 | 2010 |
Population-based PBPK model for the prediction of time-variant bile salt disposition within GI luminal fluids K Stamatopoulos, SM Pathak, L Marciani, DB Turner Molecular Pharmaceutics 17 (4), 1310-1323, 2020 | 12 | 2020 |
Stability-indicating HPTLC determination of capsaicin in the bulk drug G Subramanian, A Karthik, S Kamath, K Prabahar, A Ranjithkumar, ... JPC-Journal of Planar Chromatography-Modern TLC 21 (4), 271-275, 2008 | 12 | 2008 |
Novel liquid chromatographic method for simultaneous estimation of pioglitazone and glimepiride in rat plasma by solid phase extraction: application to preclinical … PB Musmade, KB Talole, PB Deshpande, A Karthik, SM Pathak, S Pandey, ... Arzneimittelforschung 61 (01), 23-31, 2011 | 11 | 2011 |