Cell-penetrating peptides and antimicrobial peptides: how different are they? ST Henriques, MN Melo, MARB Castanho Biochemical journal 399 (1), 1-7, 2006 | 527 | 2006 |
Mode-of-action of antimicrobial peptides: membrane disruption vs. intracellular mechanisms AH Benfield, ST Henriques Frontiers in Medical Technology 2, 610997, 2020 | 248 | 2020 |
Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds LY Chan, S Gunasekera, ST Henriques, NF Worth, SJ Le, RJ Clark, ... Blood, The Journal of the American Society of Hematology 118 (25), 6709-6717, 2011 | 243 | 2011 |
Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides L Cascales, ST Henriques, MC Kerr, YH Huang, MJ Sweet, NL Daly, ... Journal of Biological Chemistry 286 (42), 36932-36943, 2011 | 222 | 2011 |
Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities ST Henriques, YH Huang, KJ Rosengren, HG Franquelim, FA Carvalho, ... Journal of Biological Chemistry 286 (27), 24231-24241, 2011 | 205 | 2011 |
Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria IM Torcato, YH Huang, HG Franquelim, D Gaspar, DJ Craik, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (3), 944-955, 2013 | 192 | 2013 |
Cyclotides as templates in drug design ST Henriques, DJ Craik Drug discovery today 15 (1-2), 57-64, 2010 | 175 | 2010 |
Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions ST Henriques, YH Huang, MARB Castanho, LA Bagatolli, S Sonza, ... Journal of Biological Chemistry 287 (40), 33629-33643, 2012 | 146 | 2012 |
Translocation of β-galactosidase mediated by the cell-penetrating peptide pep-1 into lipid vesicles and human HeLa cells is driven by membrane electrostatic potential ST Henriques, J Costa, MARB Castanho Biochemistry 44 (30), 10189-10198, 2005 | 130 | 2005 |
Consequences of nonlytic membrane perturbation to the translocation of the cell penetrating peptide pep-1 in lipidic vesicles ST Henriques, MARB Castanho Biochemistry 43 (30), 9716-9724, 2004 | 108 | 2004 |
Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn (15–34), antimicrobial peptides from rattlesnake venom C Pérez-Peinado, SA Dias, MM Domingues, AH Benfield, JM Freire, ... Journal of Biological Chemistry 293 (5), 1536-1549, 2018 | 107 | 2018 |
Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics A Sorolla, E Wang, E Golden, C Duffy, ST Henriques, AD Redfern, ... Oncogene 39 (6), 1167-1184, 2020 | 98 | 2020 |
The prototypic cyclotide kalata B1 has a unique mechanism of entering cells ST Henriques, YH Huang, S Chaousis, MA Sani, AG Poth, F Separovic, ... Chemistry & biology 22 (8), 1087-1097, 2015 | 98 | 2015 |
Gene coevolution and regulation lock cyclic plant defence peptides to their targets EK Gilding, MA Jackson, AG Poth, ST Henriques, PJ Prentis, ... New Phytologist 210 (2), 717-730, 2016 | 95 | 2016 |
PrP (106-126) does not interact with membranes under physiological conditions ST Henriques, LK Pattenden, MI Aguilar, MARB Castanho Biophysical journal 95 (4), 1877-1889, 2008 | 92 | 2008 |
Interaction of tarantula venom peptide ProTx-II with lipid membranes is a prerequisite for its inhibition of human voltage-gated sodium channel NaV1. 7 ST Henriques, E Deplazes, N Lawrence, O Cheneval, S Chaousis, ... Journal of Biological Chemistry 291 (33), 17049-17065, 2016 | 86 | 2016 |
Anticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targeting S Troeira Henriques, YH Huang, S Chaousis, CK Wang, DJ Craik ChemBioChem 15 (13), 1956-1965, 2014 | 85 | 2014 |
The cyclic cystine ladder in θ-defensins is important for structure and stability, but not antibacterial activity AC Conibear, KJ Rosengren, NL Daly, ST Henriques, DJ Craik Journal of Biological Chemistry 288 (15), 10830-10840, 2013 | 84 | 2013 |
Converting peptides into drugs targeting intracellular protein–protein interactions GJB Philippe, DJ Craik, ST Henriques Drug Discovery Today 26 (6), 1521-1531, 2021 | 82 | 2021 |
Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium K Himeno, KJ Rosengren, T Inoue, RH Perez, ML Colgrave, HS Lee, ... Biochemistry 54 (31), 4863-4876, 2015 | 80 | 2015 |