| Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain JD Osteen, V Herzig, J Gilchrist, JJ Emrick, C Zhang, X Wang, J Castro, ... Nature 534 (7608), 494-499, 2016 | 310 | 2016 |
| Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a JR Deuis, Z Dekan, JS Wingerd, JJ Smith, NR Munasinghe, RF Bhola, ... Scientific reports 7 (1), 40883, 2017 | 151 | 2017 |
| Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ... Nature communications 5 (1), 3165, 2014 | 141 | 2014 |
| Modulating oxytocin activity and plasma stability by disulfide bond engineering M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ... Journal of medicinal chemistry 53 (24), 8585-8596, 2010 | 140 | 2010 |
| Small heat-shock proteins prevent α-synuclein aggregation via transient interactions and their efficacy is affected by the rate of aggregation D Cox, E Selig, MDW Griffin, JA Carver, H Ecroyd Journal of Biological Chemistry 291 (43), 22618-22629, 2016 | 132 | 2016 |
| Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain JR Deuis, JS Wingerd, Z Winter, T Durek, Z Dekan, SR Sousa, ... Toxins 8 (3), 78, 2016 | 119 | 2016 |
| α-Conotoxin ImI incorporating stable cystathionine bridges maintains full potency and identical three-dimensional structure Z Dekan, I Vetter, NL Daly, DJ Craik, RJ Lewis, PF Alewood Journal of the American Chemical Society 133 (40), 15866-15869, 2011 | 95 | 2011 |
| Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens FC Cardoso, Z Dekan, KJ Rosengren, A Erickson, I Vetter, JR Deuis, ... Molecular pharmacology 88 (2), 291-303, 2015 | 94 | 2015 |
| A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain J Gui, B Liu, G Cao, AM Lipchik, M Perez, Z Dekan, M Mobli, NL Daly, ... Current Biology 24 (5), 473-483, 2014 | 79 | 2014 |
| Isolation, characterization and total regioselective synthesis of the novel μO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels I Vetter, Z Dekan, O Knapp, DJ Adams, PF Alewood, RJ Lewis Biochemical pharmacology 84 (4), 540-548, 2012 | 74 | 2012 |
| Antiallodynic effects of the selective NaV1. 7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen A Mueller, H Starobova, M Morgan, Z Dekan, O Cheneval, CI Schroeder, ... Pain 160 (8), 1766-1780, 2019 | 57 | 2019 |
| Total synthesis of human hepcidin through regioselective disulfide‐bond formation by using the safety‐catch cysteine protecting group 4, 4′‐dimethylsulfinylbenzhydryl Z Dekan, M Mobli, MW Pennington, E Fung, E Nemeth, PF Alewood Angewandte Chemie 126 (11), 2975-2978, 2014 | 55 | 2014 |
| Modulatory features of the novel spider toxin μ‐TRTX‐Df1a isolated from the venom of the spider Davus fasciatus FC Cardoso, Z Dekan, JJ Smith, JR Deuis, I Vetter, V Herzig, PF Alewood, ... British journal of pharmacology 174 (15), 2528-2544, 2017 | 54 | 2017 |
| PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold B Madio, S Peigneur, YKY Chin, BR Hamilton, ST Henriques, JJ Smith, ... Cellular and molecular life sciences 75, 4511-4524, 2018 | 50 | 2018 |
| A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor Z Dekan, S Sianati, A Yousuf, KJ Sutcliffe, A Gillis, C Mallet, P Singh, ... Proceedings of the National Academy of Sciences 116 (44), 22353-22358, 2019 | 46 | 2019 |
| Development of a μO-conotoxin analogue with improved lipid membrane interactions and potency for the analgesic sodium channel NaV1. 8 JR Deuis, Z Dekan, MC Inserra, TH Lee, MI Aguilar, DJ Craik, RJ Lewis, ... Journal of Biological Chemistry 291 (22), 11829-11842, 2016 | 46 | 2016 |
| Δ‐Myrtoxin‐Mp1a is a helical heterodimer from the venom of the jack jumper ant that has antimicrobial, membrane‐disrupting, and nociceptive activities Z Dekan, SJ Headey, M Scanlon, BA Baldo, TH Lee, MI Aguilar, JR Deuis, ... Angewandte Chemie International Edition 56 (29), 8495-8499, 2017 | 36 | 2017 |
| Conotoxin Φ‐MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti‐apoptotic activity AH Jin, Z Dekan, MJ Smout, D Wilson, S Dutertre, I Vetter, RJ Lewis, ... Angewandte Chemie International Edition 56 (47), 14973-14976, 2017 | 31 | 2017 |
| Production, composition, and mode of action of the painful defensive venom produced by a limacodid caterpillar, Doratifera vulnerans AA Walker, SD Robinson, JPV Paluzzi, DJ Merritt, SA Nixon, CI Schroeder, ... Proceedings of the National Academy of Sciences 118 (18), e2023815118, 2021 | 29 | 2021 |
| Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions A Mueller, Z Dekan, Q Kaas, AJ Agwa, H Starobova, PF Alewood, ... ACS Pharmacology & Translational Science 3 (3), 535-546, 2020 | 26 | 2020 |
Paul F AlewoodEmeritus Professor, Institute for Molecular Bioscience, University of Queensland, BrisbaneEmail được xác minh tại imb.uq.edu.au
