Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein TM Klauck, MC Faux, K Labudda, LK Langeberg, S Jaken, JD Scott Science 271 (5255), 1589-1592, 1996 | 707 | 1996 |
More on target with proteinphosphorylation: conferring specificity by location MC Faux, JD Scott Trends in biochemical sciences 21 (8), 312-315, 1996 | 360 | 1996 |
Molecular glue: kinase anchoring and scaffold proteins MC Faux, JD Scott Cell 85 (1), 9-12, 1996 | 352 | 1996 |
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020 | 285 | 2020 |
Membrane‐targeting sequences on AKAP79 bind phosphatidylinositol‐4, 5‐bisphosphate ML Dell'Acqua, MC Faux, J Thorburn, A Thorburn, JD Scott The EMBO Journal, 1998 | 283 | 1998 |
Imbalance of the renin–angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target? M Garg, SG Royce, C Tikellis, C Shallue, D Batu, E Velkoska, LM Burrell, ... Gut 69 (5), 841-851, 2020 | 217 | 2020 |
Carboxyl-terminal phosphorylation regulates the function and subcellular localization of protein kinase C βII AS Edwards, MC Faux, JD Scott, AC Newton Journal of Biological Chemistry 274 (10), 6461-6468, 1999 | 186 | 1999 |
Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion MC Faux, JL Ross, C Meeker, T Johns, H Ji, RJ Simpson, MJ Layton, ... Journal of cell science 117 (3), 427-439, 2004 | 168 | 2004 |
Regulation of the AKAP79-protein kinase C interaction by Ca2+/Calmodulin MC Faux, JD Scott Journal of Biological Chemistry 272 (27), 17038-17044, 1997 | 161 | 1997 |
Wnt signaling and colon tumorigenesis—a view from the periphery AW Burgess, MC Faux, MJ Layton, RG Ramsay Experimental cell research 317 (19), 2748-2758, 2011 | 153 | 2011 |
Mechanism of A-kinase-anchoring protein 79 (AKAP79) and protein kinase C interaction MC FAUX, EN ROLLINS, AS EDWARDS, LK LANGEBERG, AC NEWTON, ... Biochemical Journal 343 (2), 443-452, 1999 | 117 | 1999 |
Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation LB Lester, MC Faux, JB Nauert, JD Scott Endocrinology 142 (3), 1218-1227, 2001 | 110 | 2001 |
Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo M Buchert, D Athineos, HE Abud, ZD Burke, MC Faux, MS Samuel, ... PLoS genetics 6 (1), e1000816, 2010 | 107 | 2010 |
PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis A Sakthianandeswaren, M Christie, C D'Andreti, C Tsui, RN Jorissen, S Li, ... Cancer Research 71 (10), 3709-3719, 2011 | 104 | 2011 |
Neurotensin receptor 1 gene activation by the Tcf/β-catenin pathway is an early event in human colonic adenomas F Souazé, V Viardot-Foucault, N Roullet, M Toy-Miou-Leong, A Gompel, ... Carcinogenesis 27 (4), 708-716, 2006 | 84 | 2006 |
Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids E Vincan, PK Darcy, CA Farrelly, MC Faux, T Brabletz, RG Ramsay Oncogene 26 (16), 2340-2352, 2007 | 82 | 2007 |
Recruitment of adenomatous polyposis coli and β-catenin to axin-puncta MC Faux, JL Coates, B Catimel, S Cody, AHA Clayton, MJ Layton, ... Oncogene 27 (44), 5808-5820, 2008 | 80 | 2008 |
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration TJ Phesse, M Buchert, E Stuart, DJ Flanagan, M Faux, S Afshar-Sterle, ... Science signaling 7 (345), ra92-ra92, 2014 | 79 | 2014 |
Independent interactions of phosphorylated β-catenin with E-cadherin at cell-cell contacts and APC at cell protrusions MC Faux, JL Coates, NJ Kershaw, MJ Layton, AW Burgess PloS one 5 (11), e14127, 2010 | 55 | 2010 |
Restoration of full‐length APC protein in SW 480 colon cancer cells induces exosome‐mediated secretion of DKK‐4 JWE Lim, RA Mathias, EA Kapp, MJ Layton, MC Faux, AW Burgess, H Ji, ... Electrophoresis 33 (12), 1873-1880, 2012 | 50 | 2012 |