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| The KEAP1-NRF2 system: a thiol-based sensor-effector apparatus for maintaining redox homeostasis M Yamamoto, TW Kensler, H Motohashi Physiological reviews 98 (3), 1169-1203, 2018 | 1516 | 2018 |
| Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice M Ramos-Gomez, MK Kwak, PM Dolan, K Itoh, M Yamamoto, P Talalay, ... Proceedings of the National Academy of Sciences 98 (6), 3410-3415, 2001 | 1396 | 2001 |
| Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis RK Thimmulappa, H Lee, T Rangasamy, SP Reddy, M Yamamoto, ... The Journal of clinical investigation 116 (4), 984-995, 2016 | 1214 | 2016 |
| Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke–induced emphysema in mice T Rangasamy, CY Cho, RK Thimmulappa, L Zhen, SS Srisuma, ... The Journal of clinical investigation 114 (9), 1248-1259, 2004 | 1181 | 2004 |
| Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers N Wakabayashi, AT Dinkova-Kostova, WD Holtzclaw, MI Kang, ... Proceedings of the National Academy of Sciences 101 (7), 2040-2045, 2004 | 1175 | 2004 |
| Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases A Cuadrado, AI Rojo, G Wells, JD Hayes, SP Cousin, WL Rumsey, ... Nature reviews Drug discovery 18 (4), 295-317, 2019 | 1156 | 2019 |
| Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors JW Fahey, X Haristoy, PM Dolan, TW Kensler, I Scholtus, KK Stephenson, ... Proceedings of the National Academy of Sciences 99 (11), 7610-7615, 2002 | 1133 | 2002 |
| Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Y Zhang, TW Kensler, CG Cho, GH Posner, P Talalay Proceedings of the National Academy of Sciences 91 (8), 3147-3150, 1994 | 1018 | 1994 |
| K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele … RH Hruban, AD Van Mansfeld, GJ Offerhaus, DH Van Weering, ... The American journal of pathology 143 (2), 545, 1993 | 896 | 1993 |
| Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis D Malhotra, E Portales-Casamar, A Singh, S Srivastava, D Arenillas, ... Nucleic acids research 38 (17), 5718-5734, 2010 | 881 | 2010 |
| Role of NRF2 in protection against hyperoxic lung injury in mice HY Cho, AE Jedlicka, SPM Reddy, TW Kensler, M Yamamoto, LY Zhang, ... American journal of respiratory cell and molecular biology 26 (2), 175-182, 2002 | 826 | 2002 |
| Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival MK Kwak, N Wakabayashi, K Itoh, H Motohashi, M Yamamoto, ... Journal of Biological Chemistry 278 (10), 8135-8145, 2003 | 825 | 2003 |
| Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology TW Kensler, BD Roebuck, GN Wogan, JD Groopman Toxicological sciences 120 (suppl_1), S28-S48, 2011 | 824 | 2011 |
| Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter MK Kwak, K Itoh, M Yamamoto, TW Kensler Molecular and cellular biology 22 (9), 2883-2892, 2002 | 735 | 2002 |
| The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice J Wakabayashi, Z Zhang, N Wakabayashi, Y Tamura, M Fukaya, ... Journal of Cell Biology 186 (6), 805-816, 2009 | 718 | 2009 |
| Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice T Rangasamy, J Guo, WA Mitzner, J Roman, A Singh, AD Fryer, ... Journal of Experimental Medicine 202 (1), 47-59, 2005 | 711 | 2005 |
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John GroopmanJohns Hopkins UniversityEmail được xác minh tại jhu.edu