| Integrins in cancer: biological implications and therapeutic opportunities JS Desgrosellier, DA Cheresh Nature Reviews Cancer 10 (1), 9-22, 2010 | 4389 | 2010 |
| Requirement of Vascular Integrin αvβ3 for Angiogenesis PC Brooks, RAF Clark, DA Cheresh Science 264 (5158), 569-571, 1994 | 4066 | 1994 |
| Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels PC Brooks, AMP Montgomery, M Rosenfeld, RA Reisfeld, T Hu, G Klier, ... Cell 79 (7), 1157-1164, 1994 | 3163 | 1994 |
| Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment TJ Wickham, P Mathias, DA Cheresh, GR Nemerow Cell 73 (2), 309-319, 1993 | 2911 | 1993 |
| Role of integrins in cell invasion and migration JD Hood, DA Cheresh Nature Reviews Cancer 2 (2), 91-100, 2002 | 2412 | 2002 |
| Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin αvβ3 PC Brooks, S Strömblad, LC Sanders, TL von Schalscha, RT Aimes, ... Cell 85 (5), 683-693, 1996 | 2146 | 1996 |
| Tumor angiogenesis: molecular pathways and therapeutic targets SM Weis, DA Cheresh Nature medicine 17 (11), 1359-1370, 2011 | 2061 | 2011 |
| Definition of two angiogenic pathways by distinct αv integrins M Friedlander, PC Brooks, RW Shaffer, CM Kincaid, JA Varner, ... Science 270 (5241), 1500-1502, 1995 | 1828 | 1995 |
| Regulation of cell motility by mitogen-activated protein kinase RL Klemke, S Cai, AL Giannini, PJ Gallagher, P Lanerolle, DA Cheresh The Journal of cell biology 137 (2), 481-492, 1997 | 1531 | 1997 |
| Tumor regression by targeted gene delivery to the neovasculature JD Hood, M Bednarski, R Frausto, S Guccione, RA Reisfeld, R Xiang, ... Science 296 (5577), 2404-2407, 2002 | 1165 | 2002 |
| Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin. PC Brooks, S Strömblad, R Klemke, D Visscher, FH Sarkar, DA Cheresh The Journal of clinical investigation 96 (4), 1815-1822, 1995 | 1141 | 1995 |
| Pathophysiological consequences of VEGF-induced vascular permeability SM Weis, DA Cheresh Nature 437 (7058), 497-504, 2005 | 1114 | 2005 |
| Detection of tumor angiogenesis in vivo by αvβ3-targeted magnetic resonance imaging DA Sipkins, DA Cheresh, MR Kazemi, LM Nevin, MD Bednarski, KCP Li Nature medicine 4 (5), 623-626, 1998 | 1102 | 1998 |
| Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability BP Eliceiri, R Paul, PL Schwartzberg, JD Hood, J Leng, DA Cheresh Molecular cell 4 (6), 915-924, 1999 | 995 | 1999 |
| The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development BP Eliceiri, DA Cheresh The Journal of clinical investigation 103 (9), 1227-1230, 1999 | 950 | 1999 |
| Disruption of angiogenesis by PEX, a noncatalytic metalloproteinase fragment with integrin binding activity PC Brooks, S Silletti, TL von Schalscha, M Friedlander, DA Cheresh Cell 92 (3), 391-400, 1998 | 878 | 1998 |
| CAS/Crk coupling serves as a “molecular switch” for induction of cell migration RL Klemke, J Leng, R Molander, PC Brooks, K Vuori, DA Cheresh Journal of Cell Biology 140 (4), 961-972, 1998 | 834 | 1998 |
| Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance L Seguin, JS Desgrosellier, SM Weis, DA Cheresh Trends in cell biology 25 (4), 234-240, 2015 | 813 | 2015 |
| Get a ligand, get a life: integrins, signaling and cell survival DG Stupack, DA Cheresh Journal of cell science 115 (19), 3729-3738, 2002 | 795 | 2002 |
| Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor. DA Cheresh Proceedings of the National Academy of Sciences 84 (18), 6471-6475, 1987 | 793 | 1987 |
