| Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers TD Barber, K McManus, KWY Yuen, M Reis, G Parmigiani, D Shen, ... Proceedings of the National Academy of Sciences 105 (9), 3443-3448, 2008 | 552 | 2008 |
| ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells KJ McManus, MJ Hendzel Molecular biology of the cell 16 (10), 5013-5025, 2005 | 309 | 2005 |
| Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing KJ McManus, IJ Barrett, Y Nouhi, P Hieter Proceedings of the National Academy of Sciences 106 (9), 3276-3281, 2009 | 207 | 2009 |
| Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability SI Houston, KJ McManus, MM Adams, JK Sims, PB Carpenter, ... Journal of Biological Chemistry 283 (28), 19478-19488, 2008 | 177 | 2008 |
| CBP, a transcriptional coactivator and acetyltransferase KJ McManus, MJ Hendzel Biochemistry and Cell Biology 79 (3), 253-266, 2001 | 144 | 2001 |
| An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development DM van Pel, IJ Barrett, Y Shimizu, BV Sajesh, BJ Guppy, T Pfeifer, ... PLoS genetics 9 (1), e1003254, 2013 | 113 | 2013 |
| Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregation KJ McManus, VL Biron, R Heit, DA Underhill, MJ Hendzel Journal of Biological Chemistry 281 (13), 8888-8897, 2006 | 113 | 2006 |
| Distinct dynamics and distribution of histone methyl-lysine derivatives in mouse development VL Biron, KJ McManus, N Hu, MJ Hendzel, DA Underhill Developmental biology 276 (2), 337-351, 2004 | 107 | 2004 |
| Quantitative analysis of CBP-and P300-induced histone acetylations in vivo using native chromatin KJ McManus, MJ Hendzel Molecular and cellular biology 23 (21), 7611-7627, 2003 | 103 | 2003 |
| Evolving therapeutic strategies to exploit chromosome instability in cancer LL Thompson, LMP Jeusset, CC Lepage, KJ McManus Cancers 9 (11), 151, 2017 | 90 | 2017 |
| Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5 DW Bell, N Sikdar, KY Lee, JC Price, R Chatterjee, HD Park, J Fox, ... PLoS genetics 7 (8), e1002245, 2011 | 89 | 2011 |
| The relationship between histone H3 phosphorylation and acetylation throughout the mammalian cell cycle KJ McManus, MJ Hendzel Biochemistry and cell biology 84 (4), 640-657, 2006 | 87 | 2006 |
| Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis LL Thompson, BJ Guppy, L Sawchuk, JR Davie, KJ McManus Cancer and Metastasis Reviews 32, 363-376, 2013 | 78 | 2013 |
| Chromosome instability; implications in cancer development, progression, and clinical outcomes R Vishwakarma, KJ McManus Cancers 12 (4), 824, 2020 | 72 | 2020 |
| Developing targeted therapies that exploit aberrant histone ubiquitination in cancer LMP Jeusset, KJ McManus Cells 8 (2), 165, 2019 | 70 | 2019 |
| Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair S Ben-Aroya, N Agmon, K Yuen, T Kwok, K McManus, M Kupiec, P Hieter PLoS genetics 6 (2), e1000852, 2010 | 70 | 2010 |
| Detecting chromosome instability in cancer: approaches to resolve cell-to-cell heterogeneity CC Lepage, CR Morden, MCL Palmer, MW Nachtigal, KJ McManus Cancers 11 (2), 226, 2019 | 63 | 2019 |
| Synthetic Lethal Targeting of Superoxide Dismutase 1 Selectively Kills RAD54B-Deficient Colorectal Cancer Cells BV Sajesh, M Bailey, Z Lichtensztejn, P Hieter, KJ McManus Genetics 195 (3), 757-767, 2013 | 61 | 2013 |
| Ubiquitin specific peptidase 22 regulates histone H2B mono-ubiquitination and exhibits both oncogenic and tumor suppressor roles in cancer LMP Jeusset, KJ McManus Cancers 9 (12), 167, 2017 | 57 | 2017 |
| The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples S Penner-Goeke, Z Lichtensztejn, M Neufeld, JL Ali, AD Altman, ... PLoS genetics 13 (4), e1006707, 2017 | 55 | 2017 |
