| Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds LY Chan, S Gunasekera, ST Henriques, NF Worth, SJ Le, RJ Clark, ... Blood, The Journal of the American Society of Hematology 118 (25), 6709-6717, 2011 | 243 | 2011 |
| High-affinity cyclic peptide matriptase inhibitors P Quimbar, U Malik, CP Sommerhoff, Q Kaas, LY Chan, YH Huang, ... Journal of Biological Chemistry 288 (19), 13885-13896, 2013 | 162 | 2013 |
| Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase–mediated biosynthesis JS Mylne, LY Chan, AH Chanson, NL Daly, H Schaefer, TL Bailey, ... The Plant Cell 24 (7), 2765-2778, 2012 | 151 | 2012 |
| Cyclotides as grafting frameworks for protein engineering and drug design applications AG Poth, LY Chan, DJ Craik Peptide Science 100 (5), 480-491, 2013 | 140 | 2013 |
| Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases MA Jackson, EK Gilding, T Shafee, KS Harris, Q Kaas, S Poon, K Yap, ... Nature Communications 9 (1), 2411, 2018 | 131 | 2018 |
| Semienzymatic cyclization of disulfide-rich peptides using Sortase A X Jia, S Kwon, CIA Wang, YH Huang, LY Chan, CC Tan, KJ Rosengren, ... Journal of biological chemistry 289 (10), 6627-6638, 2014 | 107 | 2014 |
| Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia MJ Smout, J Sotillo, T Laha, A Papatpremsiri, G Rinaldi, RN Pimenta, ... PLoS pathogens 11 (10), e1005209, 2015 | 95 | 2015 |
| Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity LY Chan, VM Zhang, Y Huang, NC Waters, PS Bansal, DJ Craik, NL Daly ChemBioChem 14 (5), 617-624, 2013 | 92 | 2013 |
| Isolation and characterization of cytotoxic cyclotides from Viola philippica W He, LY Chan, G Zeng, NL Daly, DJ Craik, N Tan Peptides 32 (8), 1719-1723, 2011 | 86 | 2011 |
| Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy LY Chan, DJ Craik, NL Daly Scientific reports 6 (1), 35347, 2016 | 82 | 2016 |
| Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium K Himeno, KJ Rosengren, T Inoue, RH Perez, ML Colgrave, HS Lee, ... Biochemistry 54 (31), 4863-4876, 2015 | 80 | 2015 |
| A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors J Du, K Yap, LY Chan, FBH Rehm, FY Looi, AG Poth, EK Gilding, Q Kaas, ... Nature Communications 11 (1), 1575, 2020 | 79 | 2020 |
| Using the MCoTI-II cyclotide scaffold to design a stable cyclic peptide antagonist of SET, a protein overexpressed in human cancer C D’Souza, ST Henriques, CK Wang, O Cheneval, LY Chan, NJ Bokil, ... Biochemistry 55 (2), 396-405, 2016 | 70 | 2016 |
| Redesigned spider peptide with improved antimicrobial and anticancer properties S Troeira Henriques, N Lawrence, S Chaousis, AS Ravipati, O Cheneval, ... ACS Chemical Biology 12 (9), 2324-2334, 2017 | 63 | 2017 |
| Short cationic peptide derived from archaea with dual antibacterial properties and anti-infective potential ES Candido, MH Cardoso, LY Chan, MDT Torres, KGN Oshiro, WF Porto, ... ACS infectious diseases 5 (7), 1081-1086, 2019 | 56 | 2019 |
| Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration LY Chan, DJ Craik, NL Daly Bioscience reports 35 (6), e00270, 2015 | 56 | 2015 |
| Isolation and Characterization of Peptides from Momordica cochinchinensis Seeds LY Chan, CKL Wang, JM Major, KP Greenwood, RJ Lewis, DJ Craik, ... Journal of Natural Products 72 (8), 1453-1458, 2009 | 56 | 2009 |
| A Computationally Designed Peptide Derived from Escherichia coli as a Potential Drug Template for Antibacterial and Antibiofilm Therapies MH Cardoso, ES Candido, LY Chan, M Der Torossian Torres, KGN Oshiro, ... ACS infectious diseases 4 (12), 1727-1736, 2018 | 49 | 2018 |
| Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus Q Du, LY Chan, EK Gilding, ST Henriques, ND Condon, AS Ravipati, ... Journal of Biological Chemistry 295 (32), 10911-10925, 2020 | 42 | 2020 |
| An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides K Yap, J Du, FY Looi, SR Tang, SJ de Veer, AR Bony, FBH Rehm, J Xie, ... Green Chemistry 22 (15), 5002-5016, 2020 | 35 | 2020 |