Theo dõi
Jean A. Bernatchez
Jean A. Bernatchez
Senior Scientist and San Diego R&D Group Leader, Eurofins Discovery
Email được xác minh tại eurofinsUS.com
Tiêu đề
Trích dẫn bởi
Trích dẫn bởi
Năm
Cysteine proteases in protozoan parasites
JL Siqueira-Neto, A Debnath, LI McCall, JA Bernatchez, M Ndao, ...
PLoS Neglected Tropical Diseases 12 (8), e0006512, 2018
1802018
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ...
Cell Stem Cell 26 (2), 187-204, 2020
1682020
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ...
Journal of Experimental Medicine 216 (5), 1071-1090, 2019
1252019
Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy
Y Luan, J Li, JA Bernatchez, R Li
Journal of Medicinal Chemistry 62 (7), 3171-3183, 2019
1222019
Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B
MH Powdrill, JA Bernatchez, M Götte
Viruses 2 (10), 2169-2195, 2010
1192010
Drugs for the Treatment of Zika Virus Infection
JA Bernatchez, LT Tran, J Li, Y Luan, JL Siqueira-Neto, R Li
Journal of Medicinal Chemistry 63 (2), 470-489, 2020
1052020
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
Z Qiu, L Zhao, JZ Shen, Z Liang, Q Wu, K Yang, L Min, RC Gimple, ...
Cancer Discovery 12 (2), 502-521, 2022
532022
Machine Learning Models Identify Inhibitors of SARS-CoV-2
VO Gawriljuk, PPK Zin, AC Puhl, KM Zorn, DH Foil, TR Lane, B Hurst, ...
Journal of Chemical Information and Modeling 61 (9), 4224-4235, 2021
522021
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies
BC Prager, HN Vasudevan, D Dixit, JA Bernatchez, Q Wu, LC Wallace, ...
Cancer Discovery 10, 1722–1741, 2020
472020
Mass spectrometry-based chemical cartography of a cardiac parasitic infection
LI McCall, JT Morton, JA Bernatchez, JL de Siqueira-Neto, R Knight, ...
Analytical chemistry 89 (19), 10414-10421, 2017
462017
Mechanism of action of methotrexate against Zika virus
S Beck, Z Zhu, MF Oliveira, DM Smith, JN Rich, JA Bernatchez, ...
Viruses 11 (4), 338, 2019
422019
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics
J Balzarini, K Das, JA Bernatchez, SE Martinez, M Ngure, S Keane, ...
Proceedings of the National Academy of Sciences 112 (11), 3475-3480, 2015
382015
Dynamics of hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B in complex with RNA
P Karam, MH Powdrill, HW Liu, C Vasquez, W Mah, J Bernatchez, M Götte, ...
Journal of Biological Chemistry 289 (20), 14399-14411, 2014
342014
Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases
L Li, BC Chenna, KS Yang, TR Cole, ZT Goodall, M Giardini, ...
Journal of Medicinal Chemistry 64 (15), 11267-11287, 2021
302021
Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting Zika virus
JA Bernatchez, Z Yang, M Coste, J Li, S Beck, Y Liu, AE Clark, Z Zhu, ...
Antimicrobial agents and chemotherapy 62 (10), 10.1128/aac. 00725-18, 2018
292018
Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors
B Singh, JA Bernatchez, LI McCall, CM Calvet, J Ackermann, JM Souza, ...
ACS Medicinal Chemistry Letters 11 (3), 249–257, 2020
272020
Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity
BC Chenna, L Li, DM Mellott, X Zhai, JL Siqueira-Neto, CM Calvet Alvarez, ...
Journal of Medicinal Chemistry 63 (6), 3298–3316, 2020
232020
Insights gained into respiratory infection pathogenesis using lung tissue metabolomics
JA Bernatchez, LI McCall
PLoS Pathogens 16 (7), e1008662, 2020
192020
Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer
M Ehteshami, M Nijhuis, JA Bernatchez, CJ Ablenas, S McCormick, ...
Journal of Biological Chemistry 288 (24), 17336-17346, 2013
182013
Nucleotide sugar pucker preference mitigates excision by HIV-1 RT
K Yamada, AS Wahba, JA Bernatchez, T Ilina, S Martínez-Montero, ...
ACS chemical biology 10 (9), 2024-2033, 2015
162015
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