Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity GL Smith, CTO Benfield, C Maluquer de Motes, M Mazzon, SWJ Ember, ... Journal of General Virology 94 (11), 2367-2392, 2013 | 345 | 2013 |
Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7 L Unterholzner, RP Sumner, M Baran, H Ren, DS Mansur, NM Bourke, ... PLoS pathogens 7 (9), e1002247, 2011 | 199 | 2011 |
Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence DS Mansur, C Maluquer de Motes, L Unterholzner, RP Sumner, ... PLoS pathogens 9 (2), e1003183, 2013 | 125 | 2013 |
KAP 1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control CHC Tie, L Fernandes, L Conde, L Robbez‐Masson, RP Sumner, ... EMBO reports 19 (10), e45000, 2018 | 115 | 2018 |
Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence BJ Ferguson, CTO Benfield, H Ren, VH Lee, GL Frazer, P Strnadova, ... Journal of General Virology 94 (9), 2070-2081, 2013 | 96 | 2013 |
Virulent poxviruses inhibit DNA sensing by preventing STING activation I Georgana, RP Sumner, GJ Towers, C Maluquer de Motes Journal of virology 92 (10), 10.1128/jvi. 02145-17, 2018 | 93 | 2018 |
Disrupting HIV‐1 capsid formation causes cGAS sensing of viral DNA RP Sumner, L Harrison, E Touizer, TP Peacock, M Spencer, ... The EMBO journal 39 (20), e103958, 2020 | 76 | 2020 |
Vaccinia virus protein C6 inhibits type I IFN signalling in the nucleus and binds to the transactivation domain of STAT2 JH Stuart, RP Sumner, Y Lu, JS Snowden, GL Smith PLoS pathogens 12 (12), e1005955, 2016 | 72 | 2016 |
DNA-PK is targeted by multiple vaccinia virus proteins to inhibit DNA sensing SR Scutts, SW Ember, H Ren, C Ye, CA Lovejoy, M Mazzon, DL Veyer, ... Cell reports 25 (7), 1953-1965. e4, 2018 | 68 | 2018 |
HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport H Khan, RP Sumner, J Rasaiyaah, CP Tan, MT Rodriguez-Plata, ... Elife 9, e60821, 2020 | 48 | 2020 |
Evasion of cGAS and TRIM5 defines pandemic HIV L Zuliani-Alvarez, ML Govasli, J Rasaiyaah, C Monit, SO Perry, ... Nature microbiology 7 (11), 1762-1776, 2022 | 43 | 2022 |
Vaccinia virus inhibits NF-κB-dependent gene expression downstream of p65 translocation RP Sumner, C Maluquer de Motes, DL Veyer, GL Smith Journal of Virology 88 (6), 3092-3102, 2014 | 43 | 2014 |
Are evolution and the intracellular innate immune system key determinants in HIV transmission? RP Sumner, LG Thorne, DL Fink, H Khan, RS Milne, GJ Towers Frontiers in immunology 8, 1246, 2017 | 42 | 2017 |
Lentiviral vector production titer is not limited in HEK293T by induced intracellular innate immunity CB Ferreira, RP Sumner, MT Rodriguez-Plata, J Rasaiyaah, RS Milne, ... Molecular Therapy Methods & Clinical Development 17, 209-219, 2020 | 39 | 2020 |
Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection DL Veyer, C Maluquer de Motes, RP Sumner, L Ludwig, BF Johnson, ... Journal of General Virology 95 (12), 2757-2768, 2014 | 38 | 2014 |
Deletion of immunomodulator C6 from vaccinia virus strain Western Reserve enhances virus immunogenicity and vaccine efficacy RP Sumner, H Ren, GL Smith Journal of General Virology 94 (5), 1121-1126, 2013 | 38 | 2013 |
Distinct monkeypox virus lineages co-circulating in humans before 2022 N Ndodo, J Ashcroft, K Lewandowski, A Yinka-Ogunleye, C Chukwu, ... Nature medicine 29 (9), 2317-2324, 2023 | 37 | 2023 |
Increased attenuation but decreased immunogenicity by deletion of multiple vaccinia virus immunomodulators RP Sumner, H Ren, BJ Ferguson, GL Smith Vaccine 34 (40), 4827-4834, 2016 | 30 | 2016 |
Enhancement of CD8+ T‐cell memory by removal of a vaccinia virus nuclear factor‐κB inhibitor H Ren, BJ Ferguson, CM de Motes, RP Sumner, LER Harman, GL Smith Immunology 145 (1), 34-49, 2015 | 26 | 2015 |
Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues C Maluquer de Motes, T Schiffner, RP Sumner, GL Smith Journal of General Virology 95 (9), 2038-2049, 2014 | 25 | 2014 |