| Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents UM Ammar, MS Abdel-Maksoud, CH Oh European Journal of Medicinal Chemistry 158, 144-166, 2018 | 50 | 2018 |
| Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl) imidazo [2, 1-b] thiazole scaffold MS Abdel-Maksoud, UM Ammar, CH Oh Bioorganic & Medicinal Chemistry 27 (10), 2041-2051, 2019 | 41 | 2019 |
| Design, synthesis, and biological evaluation of novel imidazole derivatives possessing terminal sulphonamides as potential BRAFV600Eáinhibitors EMH Ali, MS Abdel-Maksoud, UM Ammar, KI Mersal, KH Yoo, ... Bioorganic Chemistry 106, 104508, 2021 | 34 | 2021 |
| Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor EMH Ali, MS Abdel-Maksoud, RM Hassan, KI Mersal, UM Ammar, C Se-In, ... Bioorganic & Medicinal Chemistry 31, 115969, 2021 | 30 | 2021 |
| Design, synthesis, and anticancer activity of imidazo [2, 1-b] oxazole-based RAF kinase inhibitors MS Abdel-Maksoud, UM Ammar, MI El-Gamal, MMG El-Din, KI Mersal, ... Bioorganic Chemistry 93, 103349, 2019 | 27 | 2019 |
| Discovery of New Imidazo[2,1-b]thiazole Derivatives as Potent Pan-RAF Inhibitors with Promising In Vitro and In Vivo Anti-melanoma Activity MS Abdel-Maksoud, MI El-Gamal, BS Lee, MM Gamal El-Din, HR Jeon, ... Journal of Medicinal Chemistry 64 (10), 6877-6901, 2021 | 26 | 2021 |
| Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl) pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors EMH Ali, RFA El-Telbany, MS Abdel-Maksoud, UM Ammar, KI Mersal, ... European Journal of Medicinal Chemistry 215, 113277, 2021 | 22 | 2021 |
| Structural optimization of imidazothiazole derivatives affords a new promising series as B-Raf V600E inhibitors; synthesis, in vitro assay and in silico screening UM Ammar, MS Abdel-Maksoud, EMH Ali, KI Mersal, KH Yoo, CH Oh Bioorganic Chemistry 100, 103967, 2020 | 22 | 2020 |
| Modification of imidazothiazole derivatives gives promising activity in B-Raf kinase enzyme inhibition; synthesis, in vitro studies and molecular docking UM Ammar, MS Abdel-Maksoud, KI Mersal, EMH Ali, KH Yoo, HS Choi, ... Bioorganic & Medicinal Chemistry Letters 30 (20), 127478, 2020 | 16 | 2020 |
| Design and synthesis of novel pyrrolo [2, 3-b] pyridine derivatives targeting V600EBRAF MS Abdel-Maksoud, EMH Ali, UM Ammar, KI Mersal, KH Yoo, CH Oh Bioorganic & Medicinal Chemistry 28 (11), 115493, 2020 | 16 | 2020 |
| Structural optimization of 4-(imidazol-5-yl) pyridine derivatives affords broad-spectrum anticancer agents with selective B-RAFV600E/p38α kinase inhibitory activity: synthesis … EMH Ali, KI Mersal, UM Ammar, SO Zaraei, MS Abdel-Maksoud, ... European Journal of Pharmaceutical Sciences 171, 106115, 2022 | 13 | 2022 |
| Scaffold repurposing of in-house small molecule candidates leads to discovery of first-in-class CDK-1/HER-2 dual inhibitors: In vitro and in silico screening A Elkamhawy, UM Ammar, S Paik, MH Abdellattif, MH Elsherbeny, K Lee, ... Molecules 26 (17), 5324, 2021 | 13 | 2021 |
| Design, synthesis, anticancer evaluation and molecular docking of new V600EBRAF inhibitors derived from pyridopyrazinone KM Amin, OM El-Badry, DEA Rahman, UM Ammar, MM Abdalla European Journal of Chemistry 7 (1), 19-29, 2016 | 10 | 2016 |
| Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, ... European Journal of Medicinal Chemistry 261, 115779, 2023 | 7 | 2023 |
| Scaffold repurposing reveals new nanomolar phosphodiesterase type 5 (pde5) inhibitors based on pyridopyrazinone scaffold: Investigation of in vitro and in silico properties KM Amin, OM El-Badry, DE Abdel Rahman, MH Abdellattif, ... Pharmaceutics 14 (9), 1954, 2022 | 6 | 2022 |
| Design, synthesis, in vitro determination and molecular docking studies of 4-(1-(tert-butyl)-3-phenyl-1H-pyrazol-4-yl) pyridine derivatives with terminal sulfonamide … KI Mersal, MS Abdel-Maksoud, EMH Ali, UM Ammar, SO Zaraei, JM Kim, ... Medicinal Chemistry Research 30 (10), 1925-1942, 2021 | 5 | 2021 |
| 2-(3-Bromophenyl)-8-fluoroquinazoline-4-carboxylic acid as a novel and selective aurora a kinase inhibitory lead with apoptosis properties: design, synthesis, in vitro and in … MH Elsherbeny, UM Ammar, MH Abdellattif, MAS Abourehab, A Abdeen, ... Life 12 (6), 876, 2022 | 3 | 2022 |
| Synthesis and In Vitro Biological Evaluation of New Pyrido[2,3‐b]pyrazinone‐Based Cytotoxic Agents and Molecular Docking as BRAF Inhibitors K Amin, O El‐Badry, D Abdel Rahman, U Ammar ChemistrySelect 4 (30), 8882-8885, 2019 | 3 | 2019 |
| Design and Synthesis of Novel Aminoindazole-pyrrolo[2,3-b]pyridine Inhibitors of IKKα That Selectively Perturb Cellular Non-Canonical NF-κB Signalling C Riley, U Ammar, A Alsfouk, NG Anthony, J Baiget, G Berretta, D Breen, ... Molecules 29 (15), 3515, 2024 | 2 | 2024 |
| Discovery of novel naphthalene-based diarylamides as pan-Raf kinase inhibitors with promising anti-melanoma activity: rational design, synthesis, in vitro and in silico screening A Elkamhawy, UM Ammar, M Kim, AR Gul, TJ Park, K Lee Archives of Pharmacal Research, 1-16, 2025 | | 2025 |