An engineered protein tag for multiprotein labeling in living cells A Gautier, A Juillerat, C Heinis, IR Corrêa, M Kindermann, F Beaufils, ... Chemistry & biology 15 (2), 128-136, 2008 | 1297 | 2008 |
Phage-encoded combinatorial chemical libraries based on bicyclic peptides C Heinis, T Rutherford, S Freund, G Winter Nature chemical biology 5 (7), 502-507, 2009 | 846 | 2009 |
Cyclic peptide therapeutics: past, present and future A Zorzi, K Deyle, C Heinis Current opinion in chemical biology 38, 24-29, 2017 | 724 | 2017 |
Bicyclic peptide inhibitor reveals large contact interface with a protease target A Angelini, L Cendron, S Chen, J Touati, G Winter, G Zanotti, C Heinis ACS chemical biology 7 (5), 817-821, 2012 | 212 | 2012 |
Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling T Gronemeyer, C Chidley, A Juillerat, C Heinis, K Johnsson Protein Engineering, Design and Selection 19 (7), 309-316, 2006 | 203 | 2006 |
Strategies to prolong the plasma residence time of peptide drugs L Pollaro, C Heinis MedChemComm 1 (5), 319-324, 2010 | 197 | 2010 |
Phage selection of cyclic peptides for application in research and drug development K Deyle, XD Kong, C Heinis Accounts of chemical research 50 (8), 1866-1874, 2017 | 188 | 2017 |
Cyclization of peptides with two chemical bridges affords large scaffold diversities SS Kale, C Villequey, XD Kong, A Zorzi, K Deyle, C Heinis Nature chemistry 10 (7), 715-723, 2018 | 172 | 2018 |
Encoded libraries of chemically modified peptides C Heinis, G Winter Current opinion in chemical biology 26, 89-98, 2015 | 163 | 2015 |
Peptide ligands stabilized by small molecules S Chen, D Bertoldo, A Angelini, F Pojer, C Heinis Angewandte Chemie International Edition 53 (6), 1602-1606, 2014 | 155 | 2014 |
Cyclic peptides for drug development X Ji, AL Nielsen, C Heinis Angewandte Chemie 136 (3), e202308251, 2024 | 143 | 2024 |
Structurally diverse cyclisation linkers impose different backbone conformations in bicyclic peptides S Chen, J Morales‐Sanfrutos, A Angelini, B Cutting, C Heinis ChemBioChem 13 (7), 1032-1038, 2012 | 129 | 2012 |
Acylated heptapeptide binds albumin with high affinity and application as tag furnishes long-acting peptides A Zorzi, SJ Middendorp, J Wilbs, K Deyle, C Heinis Nature Communications 8 (1), 16092, 2017 | 127 | 2017 |
Tools and rules for macrocycles C Heinis Nature chemical biology 10 (9), 696-698, 2014 | 122 | 2014 |
Engineering Substrate Specificity of O6‐Alkylguanine‐DNA Alkyltransferase for Specific Protein Labeling in Living Cells A Juillerat, C Heinis, I Sielaff, J Barnikow, H Jaccard, B Kunz, A Terskikh, ... ChemBioChem 6 (7), 1263-1269, 2005 | 117 | 2005 |
Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides S Chen, R Gopalakrishnan, T Schaer, F Marger, R Hovius, D Bertrand, ... Nature chemistry 6 (11), 1009-1016, 2014 | 113 | 2014 |
Bicyclic peptide ligands pulled out of cysteine-rich peptide libraries S Chen, I Rentero Rebollo, SA Buth, J Morales-Sanfrutos, J Touati, ... Journal of the American Chemical Society 135 (17), 6562-6569, 2013 | 111 | 2013 |
Identification of target-binding peptide motifs by high-throughput sequencing of phage-selected peptides I Rentero Rebollo, M Sabisz, V Baeriswyl, C Heinis Nucleic acids research 42 (22), e169-e169, 2014 | 104 | 2014 |
Measuring in vivo protein half-life K Bojkowska, FS De Sio, I Barde, S Offner, S Verp, C Heinis, K Johnsson, ... Chemistry & biology 18 (6), 805-815, 2011 | 100 | 2011 |
De novo development of proteolytically resistant therapeutic peptides for oral administration XD Kong, J Moriya, V Carle, F Pojer, LA Abriata, K Deyle, C Heinis Nature biomedical engineering 4 (5), 560-571, 2020 | 97 | 2020 |