| Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and-independent effects by CDK6-specific PROTACs M De Dominici, P Porazzi, Y Xiao, A Chao, HY Tang, G Kumar, P Fortina, ... Blood, The Journal of the American Society of Hematology 135 (18), 1560-1573, 2020 | 71 | 2020 |
| Structure-based screen identifies a potent small molecule inhibitor of Stat5a/b with therapeutic potential for prostate cancer and chronic myeloid leukemia Z Liao, L Gu, J Vergalli, SA Mariani, M De Dominici, RK Lokareddy, ... Molecular cancer therapeutics 14 (8), 1777-1793, 2015 | 53 | 2015 |
| c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells T Waldron, M De Dominici, AR Soliera, A Audia, I Iacobucci, A Lonetti, ... Leukemia 26 (4), 644-653, 2012 | 51 | 2012 |
| Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors KC Higa, A Goodspeed, JS Chavez, M De Dominici, E Danis, ... Journal of Experimental Medicine 218 (6), e20200560, 2021 | 49 | 2021 |
| Structure of nascent chromatin is essential for hematopoietic lineage specification S Petruk, SA Mariani, M De Dominici, P Porazzi, V Minieri, J Cai, ... Cell reports 19 (2), 295-306, 2017 | 38 | 2017 |
| Targeting STAT5 or STAT5-regulated pathways suppresses leukemogenesis of Ph+ acute lymphoblastic leukemia V Minieri, M De Dominici, P Porazzi, SA Mariani, O Spinelli, A Rambaldi, ... Cancer research 78 (20), 5793-5807, 2018 | 29 | 2018 |
| Targeting CDK6 and BCL2 exploits the “MYB addiction” of Ph+ acute lymphoblastic leukemia M De Dominici, P Porazzi, AR Soliera, SA Mariani, S Addya, P Fortina, ... Cancer research 78 (4), 1097-1109, 2018 | 28 | 2018 |
| Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb S D’Aguanno, E Valentini, MG Tupone, M Desideri, M Di Martile, ... Journal of Experimental & Clinical Cancer Research 37, 1-14, 2018 | 27 | 2018 |
| Targeting chemotherapy to decondensed H3K27me3-marked chromatin of AML cells enhances leukemia suppression P Porazzi, S Petruk, L Pagliaroli, M De Dominici, D Deming, MV Puccetti, ... Cancer research 82 (3), 458-471, 2022 | 22 | 2022 |
| Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells M Spagnuolo, G Regazzo, M De Dominici, A Sacconi, A Pelosi, E Korita, ... Haematologica 104 (1), 82, 2018 | 22 | 2018 |
| Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2 B Riva, M De Dominici, I Gnemmi, SA Mariani, A Minassi, V Minieri, ... Oncotarget 7 (49), 81555, 2016 | 19 | 2016 |
| CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia SA Mariani, V Minieri, M De Dominici, I Iacobucci, LF Peterson, ... Leukemia 30 (8), 1682-1690, 2016 | 14 | 2016 |
| Targeting the CDK6 dependence of Ph+ acute lymphoblastic leukemia P Porazzi, M De Dominici, J Salvino, B Calabretta Genes 12 (9), 1355, 2021 | 7 | 2021 |
| Our ancestry dictates clonal architecture and skin cancer susceptibility M De Dominici, J DeGregori Nature Genetics 55 (9), 1428-1429, 2023 | 3 | 2023 |
| A phase I study of the combination of palbociclib and dexamethasone for the treatment of relapsed or refractory B-cell acute lymphoblastic leukemia L Wilde, P Porazzi, R Trotta, M De Dominici, N Palmisiano, G Keiffer, ... Leukemia Research 129, 107075, 2023 | 3 | 2023 |
| CHIP: a clonal odyssey of the bone marrow niche WE Schleicher, B Hoag, M De Dominici, J DeGregori, EM Pietras The Journal of Clinical Investigation 134 (15), 2024 | 1 | 2024 |
| Shedding light on mutant clonal dynamics and Cancer risk in the skin M De Dominici, J DeGregori Cancer Discovery 11 (2), 227-229, 2021 | 1 | 2021 |
| Targeting the STAT5 pathway in Ph+ acute lymphoblastic leukemia V Minieri, M De Dominici, MT Nevalainen, B Calabretta Oncotarget 9 (95), 36726, 2018 | 1 | 2018 |
| In Vivo Clonal Tracing of Hematopoietic Stem and Progenitor Cells Reveals Increased Clonal Heterogeneity during Aging, Alongside Critical Changes in Selection Patterns L Naddaf, M De Dominici, X Chen, P Kumar, JS Chavez, T Roeder, ... Blood 144, 2671, 2024 | | 2024 |
| Hematopoietic Stem Cell Aging Promotes Expansion of Tet2 Mutant Clones By Cell Intrinsic Mechanisms M De Dominici, L Naddaf, V Zaberezhnyy, A Goodspeed, S Li, ... Blood 144, 191, 2024 | | 2024 |
