| Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration I Choi, Y Zhang, SP Seegobin, M Pruvost, Q Wang, K Purtell, B Zhang, ... Nature communications 11 (1), 1386, 2020 | 423 | 2020 |
| Complement C3aR inactivation attenuates tau pathology and reverses an immune network deregulated in tauopathy models and Alzheimer’s disease A Litvinchuk, YW Wan, DB Swartzlander, F Chen, A Cole, NE Propson, ... Neuron 100 (6), 1337-1353. e5, 2018 | 401 | 2018 |
| The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ... Scientific data 5 (1), 1-16, 2018 | 382 | 2018 |
| Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ... Science advances 7 (2), eabb5398, 2021 | 217 | 2021 |
| ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway Z Deng, J Lim, Q Wang, K Purtell, S Wu, GM Palomo, H Tan, G Manfredi, ... Autophagy 16 (5), 917-931, 2020 | 173 | 2020 |
| Parkinson's disease-associated LRRK2 hyperactive kinase mutant disrupts synaptic vesicle trafficking in ventral midbrain neurons PY Pan, X Li, J Wang, J Powell, Q Wang, Y Zhang, Z Chen, B Wicinski, ... Journal of Neuroscience 37 (47), 11366-11376, 2017 | 148 | 2017 |
| Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ... Neuron 109 (2), 257-272. e14, 2021 | 139 | 2021 |
| The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease Q Wang, Y Zhang, M Wang, WM Song, Q Shen, A McKenzie, I Choi, ... Nature communications 10 (1), 5234, 2019 | 106 | 2019 |
| Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease E Horgusluoglu, R Neff, WM Song, M Wang, Q Wang, M Arnold, ... Alzheimer's & Dementia 18 (6), 1260-1278, 2022 | 103 | 2022 |
| The landscape of human tissue and cell type specific expression and co-regulation of senescence genes P Xu, M Wang, W Song, Q Wang, GC Yuan, PH Sudmant, H Zare, Z Tu, ... Molecular neurodegeneration 17, 1-20, 2022 | 79 | 2022 |
| Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence I Choi, M Wang, S Yoo, P Xu, SP Seegobin, X Li, X Han, Q Wang, J Peng, ... Nature cell biology 25 (7), 963-974, 2023 | 78 | 2023 |
| Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application M Wang, W Song, C Ming, Q Wang, X Zhou, P Xu, A Krek, Y Yoon, L Ho, ... Molecular neurodegeneration 17 (1), 17, 2022 | 67 | 2022 |
| Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice V Lachance, Q Wang, E Sweet, I Choi, CZ Cai, XX Zhuang, Y Zhang, ... Molecular neurodegeneration 14, 1-13, 2019 | 62 | 2019 |
| Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice PY Pan, P Sheehan, Q Wang, X Zhu, Y Zhang, I Choi, X Li, J Saenz, J Zhu, ... Human molecular genetics 29 (14), 2300-2312, 2020 | 44 | 2020 |
| The hippocampal proteomic analysis of senescence-accelerated mouse: implications of Uchl3 and mitofilin in cognitive disorder and mitochondria dysfunction in SAMP8 Q Wang, Y Liu, X Zou, Q Wang, M An, X Guan, J He, Y Tong, J Ji Neurochemical Research 33, 1776-1782, 2008 | 32 | 2008 |
| Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease Q Wang, M Wang, I Choi, L Sarrafha, M Liang, L Ho, K Farrell, ... Science advances 10 (2), eadi8287, 2024 | 27 | 2024 |
| Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression SG Choi, Q Wang, J Jia, H Pincas, JL Turgeon, SC Sealfon Journal of Biological Chemistry 289 (23), 16164-16175, 2014 | 26 | 2014 |
| Outside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation H Pincas, SG Choi, Q Wang, J Jia, JL Turgeon, SC Sealfon Molecular and cellular endocrinology 385 (1-2), 56-61, 2014 | 23 | 2014 |
| Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models CZ Cai, XX Zhuang, Q Zhu, MY Wu, H Su, X Wang, A Iyaswamy, Z Yue, ... Theranostics 12 (4), 1738, 2022 | 22 | 2022 |
| Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice L Chen, N Yang, Y Li, Y Li, J Hong, Q Wang, K Liu, D Han, Y Han, X Mi, ... CNS Neuroscience & Therapeutics 27 (11), 1374-1384, 2021 | 21 | 2021 |