G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine N Murakami, T Yokomizo, T Okuno, T Shimizu Journal of Biological Chemistry 279 (41), 42484-42491, 2004 | 280 | 2004 |
12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid is a natural ligand for leukotriene B4 receptor 2 T Okuno, Y Iizuka, H Okazaki, T Yokomizo, R Taguchi, T Shimizu The Journal of experimental medicine 205 (4), 759-766, 2008 | 230 | 2008 |
The role of leukotrienes as potential therapeutic targets in allergic disorders A Jo-Watanabe, T Okuno, T Yokomizo International journal of molecular sciences 20 (14), 3580, 2019 | 146 | 2019 |
Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor δ2 subunit Y Miyagi, T Yamashita, M Fukaya, T Sonoda, T Okuno, K Yamada, ... Journal of Neuroscience 22 (3), 803-814, 2002 | 139 | 2002 |
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor M Liu, K Saeki, T Matsunobu, T Okuno, T Koga, Y Sugimoto, C Yokoyama, ... Journal of Experimental Medicine 211 (6), 1063-1078, 2014 | 135 | 2014 |
Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis Y Iizuka, T Okuno, K Saeki, H Uozaki, S Okada, T Misaka, T Sato, H Toh, ... The FASEB Journal 24 (12), 4678-4690, 2010 | 120 | 2010 |
Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1 T Hori, T Okuno, K Hirata, K Yamashita, Y Kawano, M Yamamoto, M Hato, ... Nature chemical biology 14 (3), 262-269, 2018 | 92 | 2018 |
Determination of double bond positions in polyunsaturated fatty acids using the photochemical Paterno-Buchi reaction with acetone and tandem mass spectrometry RC Murphy, T Okuno, CA Johnson, RM Barkley Analytical chemistry 89 (16), 8545-8553, 2017 | 86 | 2017 |
Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2 S Iwamoto, T Koga, M Ohba, T Okuno, M Koike, A Murakami, A Matsuda, ... Scientific reports 7 (1), 13267, 2017 | 80 | 2017 |
Leukotriene B4 receptor and the function of its helix 8 T Okuno, T Yokomizo, T Hori, M Miyano, T Shimizu Journal of Biological Chemistry 280 (37), 32049-32052, 2005 | 78 | 2005 |
Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand [S] T Matsunobu, T Okuno, C Yokoyama, T Yokomizo Journal of lipid research 54 (11), 2979-2987, 2013 | 74 | 2013 |
Helix 8 of the leukotriene B4 receptor is required for the conformational change to the low affinity state after G-protein activation T Okuno, H Ago, K Terawaki, M Miyano, T Shimizu, T Yokomizo Journal of Biological Chemistry 278 (42), 41500-41509, 2003 | 62 | 2003 |
Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins Y Ishii, K Saeki, M Liu, F Sasaki, T Koga, K Kitajima, C Meno, T Okuno, ... The FASEB Journal 30 (2), 933-947, 2016 | 58 | 2016 |
Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia Y Matsunaga, S Fukuyama, T Okuno, F Sasaki, T Matsunobu, Y Asai, ... The FASEB Journal 27 (8), 3306-3314, 2013 | 57 | 2013 |
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models F Sasaki, T Koga, M Ohba, K Saeki, T Okuno, K Ishikawa, T Nakama, ... JCI insight 3 (18), 2018 | 52 | 2018 |
From the cover: prolonged exposure to volatile anesthetic isoflurane worsens the outcome of polymicrobial abdominal sepsis S Koutsogiannaki, MM Schaefers, T Okuno, M Ohba, T Yokomizo, ... Toxicological Sciences 156 (2), 402-411, 2017 | 46 | 2017 |
A high-affinity monoclonal antibody against the FLAG tag useful for G-protein-coupled receptor study F Sasaki, T Okuno, K Saeki, L Min, N Onohara, H Kato, T Shimizu, ... Analytical biochemistry 425 (2), 157-165, 2012 | 46 | 2012 |
Chemical study on hapalosin, a cyclic depsipeptide possessing multidrug resistance reversing activities: Synthesis, structure and biological activity T Okuno, K Ohmori, S Nishiyama, S Yamamura, K Nakamura, KN Houk, ... Tetrahedron 52 (47), 14723-14734, 1996 | 46 | 1996 |
Identification of the intracellular region of the leukotriene B4 receptor type 1 that is specifically involved in Gi activation K Kuniyeda, T Okuno, K Terawaki, M Miyano, T Yokomizo, T Shimizu Journal of Biological Chemistry 282 (6), 3998-4006, 2007 | 45 | 2007 |
Eicosanoids in skin wound healing K Yasukawa, T Okuno, T Yokomizo International Journal of Molecular Sciences 21 (22), 8435, 2020 | 44 | 2020 |