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Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa, S Ramachandran, ... Nature 487 (7405), 109-113, 2012 | 994 | 2012 |
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ... Science 321 (5897), 1837-1841, 2008 | 908 | 2008 |
Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system BL Davidson, CS Stein, JA Heth, I Martins, RM Kotin, TA Derksen, ... Proceedings of the National Academy of Sciences 97 (7), 3428-3432, 2000 | 884 | 2000 |
Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis J Zabner, LA Couture, RJ Gregory, SM Graham, AE Smith, MJ Welsh Cell 75 (2), 207-216, 1993 | 853 | 1993 |
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ... Science translational medicine 2 (29), 29ra31-29ra31, 2010 | 596 | 2010 |
Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity N Kaludov, KE Brown, RW Walters, J Zabner, JA Chiorini Journal of virology 75 (15), 6884-6893, 2001 | 559 | 2001 |
Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape RW Walters, P Freimuth, TO Moninger, I Ganske, J Zabner, MJ Welsh Cell 110 (6), 789-799, 2002 | 502 | 2002 |
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Binding of adeno-associated virus type 5 to 2, 3-linked sialic acid is required for gene transfer RW Walters, SMP Yi, S Keshavjee, KE Brown, MJ Welsh, JA Chiorini, ... Journal of Biological Chemistry 276 (23), 20610-20616, 2001 | 469 | 2001 |
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia AA Pezzulo, TD Starner, TE Scheetz, GL Traver, AE Tilley, BG Harvey, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (1 …, 2011 | 441 | 2011 |
Segregation of receptor and ligand regulates activation of epithelial growth factor receptor PD Vermeer, LA Einwalter, TO Moninger, T Rokhlina, JA Kern, J Zabner, ... Nature 422 (6929), 322-326, 2003 | 435 | 2003 |
Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis MJ Hoegger, AJ Fischer, JD McMenimen, LS Ostedgaard, AJ Tucker, ... Science 345 (6198), 818-822, 2014 | 428 | 2014 |
An in vitro model of differentiated human airway epithelia: methods for establishing primary cultures PH Karp, TO Moninger, S Pary Weber, TS Nesselhauf, JL Launspach, ... Epithelial cell culture protocols, 115-137, 2002 | 417 | 2002 |
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Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia CK Chun, EA Ozer, MJ Welsh, J Zabner, EP Greenberg Proceedings of the National Academy of Sciences 101 (10), 3587-3590, 2004 | 378 | 2004 |
Practical reconstruction method for bioluminescence tomography W Cong, G Wang, D Kumar, Y Liu, M Jiang, LV Wang, EA Hoffman, ... Optics Express 13 (18), 6756-6771, 2005 | 362 | 2005 |
A mouse model for the delta F508 allele of cystic fibrosis. BG Zeiher, E Eichwald, J Zabner, JJ Smith, AP Puga, PB McCray, ... The Journal of clinical investigation 96 (4), 2051-2064, 1995 | 360 | 1995 |
Airway acidification initiates host defense abnormalities in cystic fibrosis mice VS Shah, DK Meyerholz, XX Tang, L Reznikov, M Abou Alaiwa, SE Ernst, ... Science 351 (6272), 503-507, 2016 | 348 | 2016 |