Current mechanistic concepts in ischemia and reperfusion injury MY Wu, GT Yiang, WT Liao, APY Tsai, YL Cheng, PW Cheng, CY Li, CJ Li Cellular Physiology and Biochemistry 46 (4), 1650-1667, 2018 | 1341 | 2018 |
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia MS Haney, R Pálovics, CN Munson, C Long, PK Johansson, O Yip, ... Nature 628 (8006), 154-161, 2024 | 116 | 2024 |
INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia AP Tsai, PBC Lin, C Dong, M Moutinho, BT Casali, Y Liu, BT Lamb, ... Neurobiology of disease 153, 105303, 2021 | 85 | 2021 |
Molecular regulation of bone metastasis pathogenesis MY Wu, CJ Li, GT Yiang, YL Cheng, APY Tsai, YT Hou, YC Ho, MF Hou, ... Cellular Physiology and Biochemistry 46 (4), 1423-1438, 2018 | 76 | 2018 |
PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease AP Tsai, C Dong, PBC Lin, EJ Messenger, BT Casali, M Moutinho, Y Liu, ... Genome Medicine 14 (1), 17, 2022 | 71 | 2022 |
Epithelial to mesenchymal transition and cell biology of molecular regulation in endometrial carcinogenesis HC Chiu, CJ Li, GT Yiang, APY Tsai, MY Wu Journal of clinical medicine 8 (4), 439, 2019 | 67 | 2019 |
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease M Moutinho, SS Puntambekar, AP Tsai, I Coronel, PB Lin, BT Casali, ... Science translational medicine 14 (637), eabl7634, 2022 | 62 | 2022 |
An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice CH Yang, YC Chen, SY Peng, APY Tsai, TJF Lee, JH Yen, JW Liou Scientific reports 8 (1), 14602, 2018 | 55 | 2018 |
STAT1 mediates oroxylin a inhibition of iNOS and pro-inflammatory cytokines expression in microglial BV-2 cells PW Liu, MF Chen, APY Tsai, TJF Lee PLoS One 7 (12), e50363, 2012 | 45 | 2012 |
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ... Alzheimer's & Dementia 18 (10), 1765-1778, 2022 | 34 | 2022 |
INPP5D deficiency attenuates amyloid pathology in a mouse model of Alzheimer's disease PBC Lin, APY Tsai, D Soni, A Lee‐Gosselin, M Moutinho, ... Alzheimer's & Dementia 19 (6), 2528-2537, 2023 | 32 | 2023 |
Metabolic defects caused by high-fat diet modify disease risk through inflammatory and amyloidogenic pathways in a mouse model of Alzheimer’s disease AM Reilly, AP Tsai, PB Lin, AC Ericsson, AL Oblak, H Ren Nutrients 12 (10), 2977, 2020 | 32 | 2020 |
Over-activated proteasome mediates neuroinflammation on acute intracerebral hemorrhage in rats HK Liew, WF Hu, PBC Lin, PK Wang, APY Tsai, CY Pang, TY Chen Cells 8 (11), 1326, 2019 | 21 | 2019 |
Advanced evolution of pathogenesis concepts in cardiomyopathies CJ Li, CS Chen, GT Yiang, APY Tsai, WT Liao, MY Wu Journal of clinical medicine 8 (4), 520, 2019 | 21 | 2019 |
Genetic variants of phospholipase C-γ2 alter the phenotype and function of microglia and confer differential risk for Alzheimer’s disease AP Tsai, C Dong, PBC Lin, AL Oblak, GV Di Prisco, N Wang, N Hajicek, ... Immunity 56 (9), 2121-2136. e6, 2023 | 19 | 2023 |
TREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation M Moutinho, I Coronel, AP Tsai, GV Di Prisco, T Pennington, BK Atwood, ... Genome Medicine 15 (1), 11, 2023 | 17 | 2023 |
Energy homeostasis and abnormal RNA metabolism in amyotrophic lateral sclerosis YJ Liu, PY Tsai, Y Chern Frontiers in Cellular Neuroscience 11, 126, 2017 | 15 | 2017 |
Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer’s Disease-Relevant Phenotypes in Mice AL Oblak, KP Kotredes, RS Pandey, AM Reagan, C Ingraham, B Perkins, ... Frontiers in Aging Neuroscience 14, 886575, 2022 | 14 | 2022 |
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia MS Haney, R Palovics, CN Munson, C Long, P Johansson, O Yip, ... bioRxiv, 2023 | 13 | 2023 |
Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration L Zhou, K Nho, MG Haddad, N Cherepacha, A Tubeleviciute-Aydin, ... Scientific Reports 11 (1), 12695, 2021 | 12 | 2021 |