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Birgit Goversen
Birgit Goversen
Project leader, 3Rs Centre Utrecht, Utrecht, the Netherlands
在 uu.nl 的电子邮件经过验证
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3D bioprinting of methacrylated hyaluronic acid (MeHA) hydrogel with intrinsic osteogenicity
MT Poldervaart, B Goversen, M De Ruijter, A Abbadessa, FPW Melchels, ...
PloS one 12 (6), e0177628, 2017
3792017
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on IK1
B Goversen, MAG van der Heyden, TAB van Veen, TP de Boer
Pharmacology & therapeutics 183, 127-136, 2018
1762018
A hybrid model for safety pharmacology on an automated patch clamp platform: Using dynamic clamp to join iPSC-derived cardiomyocytes and simulations of Ik1 ion channels in real …
B Goversen, N Becker, S Stoelzle-Feix, A Obergrussberger, MA Vos, ...
Frontiers in Physiology 8, 1094, 2018
542018
Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling
S Vučković, R Dinani, EE Nollet, DWD Kuster, JW Buikema, ...
Stem cell research & therapy 13 (1), 332, 2022
412022
Required GK1 to suppress automaticity of iPSC-CMs depends strongly on IK1 model structure
A Fabbri, B Goversen, MA Vos, TAB van Veen, TP de Boer
Biophysical Journal 117 (12), 2303-2315, 2019
202019
The influence of hERG1a and hERG1b isoforms on drug safety screening in iPSC-CMs
B Goversen, MKB Jonsson, NHL van den Heuvel, R Rijken, MA Vos, ...
Progress in Biophysics and Molecular Biology 149, 86-98, 2019
92019
A systematic literature review of economic evaluations and cost-of-illness studies of inherited cardiomyopathies
I Wiethoff, B Goversen, M Michels, J van der Velden, M Hiligsmann, ...
Netherlands Heart Journal 31 (6), 226-237, 2023
62023
üner FC, Dhert WJ, Vermonden T, Alblas J
MT Poldervaart, B Goversen, M De Ruijter, A Abbadessa, FP Melchels
PLoS One 12 (6), 2017
62017
PITX2 induction leads to impaired cardiomyocyte function in arrhythmogenic cardiomyopathy
SJ van Kampen, SJ Han, WB van Ham, E Kyriakopoulou, EW Stouthart, ...
Stem Cell Reports 18 (3), 749-764, 2023
42023
Commentary: Reciprocal Modulation of IK1–INa Extends Excitability in Cardiac Ventricular Cells
B Goversen, TP de Boer, MAG van der Heyden
Frontiers in Physiology 7, 647, 2016
42016
Developing a global education hub for animal-free innovation
MRE Janssens, D Salvatori, J Hogervorst, C Nonis, J Bailey, J Bajramovic, ...
ALTEX-Alternatives to animal experimentation, 2025
2025
Experimental Models of Hypertrophic Cardiomyopathy: A Systematic Review
FW van den Dolder, R Dinani, VAJ Warnaar, S Vučković, AS Passadouro, ...
JACC: Basic to Translational Science, 2025
2025
Reply to ‘Cost-effectiveness of long term left ventricular assist devices’
I Wiethoff, B Goversen, M Michels, J van der Velden, M Hiligsmann, ...
Netherlands Heart Journal, 1-1, 2024
2024
Gender differences in pursuing leadership positions in the Netherlands; a study in cardiovascular PhD candidates
EL Kessler, B Goversen, B Derks, HM Den Ruijter
European Heart Journal 41 (Supplement_2), ehaa946. 3570, 2020
2020
Modulating human iPSC-CM electrophysiology for in vitro drug screening
B Goversen
Utrecht University, 2020
2020
A Novel Desmoplakin Mutation Contributes to Arrhythmogenic Cardiomyopathy
SJ van Kampen, E Kyriakopoulou, SJ Han, B Goversen, ...
Circulation Research 125 (Suppl_1), A786-A786, 2019
2019
Integrating dynamic clamping with automated patch clamping devices: adding virtual IK1 channels to iPSC-CM
B Goversen, N Becker, S Stoelzle-Feix, A Obergrussberger, ...
Journal of Pharmacological and Toxicological Methods 93, 142-142, 2018
2018
Identification and characterization of a novel desmoplakin mutation in a patient diagnosed with arrhythmogenic cardiomyopathy
SJ van Kampen, J Monshouwer-Kloots, B Goversen, E Kyriakopoulou, ...
Journal of Molecular and Cellular Cardiology 120, 52, 2018
2018
Introducing Simulated IK1 into Human iPSC-Cardiomyocytes using Dynamic Clamp on an Automated Patch Clamp Platform
C Bot, N Becker, B Goversen, S Stoelzle-Feix, A Obergrussberger, ...
Biophysical Journal 114 (3), 308a, 2018
2018
Mechanics in articular cartilage regeneration
B Goversen
2015
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